Click here to switch to the map view.

The map label for this gene is sapD [H]

Identifier: 218549015

GI number: 218549015

Start: 1709309

End: 1710301

Strand: Direct

Name: sapD [H]

Synonym: EFER_1663

Alternate gene names: 218549015

Gene position: 1709309-1710301 (Clockwise)

Preceding gene: 218549014

Following gene: 218549016

Centisome position: 37.25

GC content: 49.14

Gene sequence:

>993_bases
ATGCCGTTACTCGATATCCGCAATTTGACCATCGAATTCAAAACTGGCGATGAATGGGTTAAAGCCGTTGACCGTGTCAG
CATGACCTTAAATGAAGGTGAAATACGCGGCCTGGTAGGAGAATCTGGTTCAGGTAAAAGTCTGATTGCTAAAGCGATCT
GTGGCGTTGCCAAAGACAACTGGCGCGTGACGGCTGATCGTATGCGCTTTGATGACATTGATCTGCTTCGTCTTTCCGCA
CGCGAACGCCGAAAACTGGTTGGGCATAACGTGTCGATGATTTTCCAGGAGCCACAATCTTGTCTTGATCCTTCTGAACG
AGTGGGTCGGCAACTGATGCAAAATATCCCGGCATGGACTTACAAAGGCCGTTGGTGGCAACGTCCAGGCTGGCGGAAAC
GTCGTGCTATTGAGTTGTTACACCGTGTAGGGATTAAAGATCACAAAGATGCAATGCGCAGTTTTCCTTACGAACTCACT
GAAGGTGAATGCCAGAAGGTGATGATTGCCATCGCCCTGGCAAATCAACCGCGTTTGCTGATTGCGGATGAACCGACAAA
CTCGATGGAACCGACAACTCAGGCGCAGATATTCCGTCTGTTGACGCGTCTGAATCAAAATAGCAATACCACCATTTTGT
TGATTAGCCATGACCTGCAAATGCTTAGCCAGTGGGCGGATAAAATCAACGTTCTTTACTGCGGGCAAACGGTGGAATCT
GCCCCGAGTAAGGAGTTAGTGACGATGCCACATCACCCTTATACTCAGGCGTTGATCCGCGCAATTCCTGACTTTGGTAG
CGCAATGCCGCATAAAAGCCGTCTGAATACGATGCCTGGCGCGATTCCCTTGCTGGAGCAATTACCTATAGGTTGTCGTC
TTGGCCCACGTTGCCCCTATGCTCAACGAGAATGTATCGTGACACCACGTCTGACTGGTGCGAAAAATCATCTCTATGCC
TGTCATTTTCCACTGAATATGGAGAGAGAGTGA

Upstream 100 bases:

>100_bases
GGACCGTTATGCTGCCAGGTGCAGCAATTATGATCAGCGTTTTGTTAGTTAACTTACTCGGTGACGGAATACGCCGGGCC
ATTATTGCGGGGGTGGAATA

Downstream 100 bases:

>100_bases
GATGGTCGAAACCCTACTCGAAGTACGTAATCTGAGTAAAACGTTCCGCTACCGGACCGGCTGGTTTCGTCGTCAAACCG
TAGAAGCAGTCAAACCGCTA

Product: antimicrobial peptide ABC transporter ATP-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLNEGEIRGLVGESGSGKSLIAKAICGVAKDNWRVTADRMRFDDIDLLRLSA
RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRPGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVES
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTMPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYA
CHFPLNMERE

Sequences:

>Translated_330_residues
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLNEGEIRGLVGESGSGKSLIAKAICGVAKDNWRVTADRMRFDDIDLLRLSA
RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRPGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVES
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTMPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYA
CHFPLNMERE
>Mature_329_residues
PLLDIRNLTIEFKTGDEWVKAVDRVSMTLNEGEIRGLVGESGSGKSLIAKAICGVAKDNWRVTADRMRFDDIDLLRLSAR
ERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRPGWRKRRAIELLHRVGIKDHKDAMRSFPYELTE
GECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVESA
PSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTMPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYAC
HFPLNMERE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=98.1818181818182, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=43.2926829268293, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=38.109756097561, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=36.7283950617284, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=33.434650455927, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI145693107, Length=274, Percent_Identity=34.3065693430657, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788506, Length=269, Percent_Identity=35.6877323420074, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1787758, Length=316, Percent_Identity=30.6962025316456, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=29.6416938110749, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787547, Length=274, Percent_Identity=28.1021897810219, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786398, Length=290, Percent_Identity=29.3103448275862, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI48994997, Length=263, Percent_Identity=29.6577946768061, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789890, Length=239, Percent_Identity=30.1255230125523, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87081834, Length=229, Percent_Identity=31.0043668122271, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1789891, Length=259, Percent_Identity=30.1158301158301, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789032, Length=245, Percent_Identity=25.7142857142857, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787105, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788225, Length=262, Percent_Identity=26.3358778625954, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790544, Length=240, Percent_Identity=28.75, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081791, Length=264, Percent_Identity=26.5151515151515, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788450, Length=242, Percent_Identity=25.2066115702479, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786703, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787792, Length=245, Percent_Identity=31.0204081632653, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787712, Length=275, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789672, Length=267, Percent_Identity=26.5917602996255, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787029, Length=243, Percent_Identity=24.2798353909465, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790162, Length=264, Percent_Identity=21.5909090909091, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=250, Percent_Identity=25.2, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=24.5136186770428, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788644, Length=129, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI48995001, Length=241, Percent_Identity=29.045643153527, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788165, Length=285, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=26.4840182648402, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=264, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082267, Length=248, Percent_Identity=22.9838709677419, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37613; Mature: 37482

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLNEGEIRGLVGESGSGKSLIAKAICGVAKDN
CCCEEEECEEEEEECCHHHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHCCCCC
WRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWT
CEEEHHHCCCCCHHHHHHHHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCE
YKGRWWQRPGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLL
ECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVES
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCHHCC
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTMPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIVTPRLTGAKNHLYACHFPLNMERE
CCCCEEECCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEFKTGDEWVKAVDRVSMTLNEGEIRGLVGESGSGKSLIAKAICGVAKDN
CCEEEECEEEEEECCHHHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHHCCCCC
WRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWT
CEEEHHHCCCCCHHHHHHHHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCE
YKGRWWQRPGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLL
ECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVES
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCHHCC
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTMPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHCCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIVTPRLTGAKNHLYACHFPLNMERE
CCCCEEECCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]