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The map label for this gene is sapB [H]

Identifier: 218549013

GI number: 218549013

Start: 1707467

End: 1708432

Strand: Direct

Name: sapB [H]

Synonym: EFER_1661

Alternate gene names: 218549013

Gene position: 1707467-1708432 (Clockwise)

Preceding gene: 218549012

Following gene: 218549014

Centisome position: 37.21

GC content: 48.34

Gene sequence:

>966_bases
ATGATTATTTTCACCCTGCGACGCATTCTACTCTTGCTGGTCACTCTTTTCTTTCTGACCTTTGTGGGCTTTAGCCTTAA
TTACTTTACACCCCACGCACCGTTACAAGGTGCATCGCTGTGGAACGCCTGGGTTTTCTGGTTTGATGGTTTATTGCATT
GGGATTTTGGCGTTTCCAGTATTAACGGGCAACTTATCTCGGAACAACTGAAAGAAGTGTTCCCGGCGACGATGGAGCTG
TGCATCCTCGCTTTTGGTTTCGCCCTGATTGTTGGTATTCCCATCGGTATGGTTGCTGGAATCATGCGTGGAAAATGGCA
GGATCAACTTATCAACGCTCTGGCGCTGTTAGGTTTTTCCATCCCTGTTTTCTGGCTGGCGCTGTTGCTGACGCTATTCT
GTTCGCTCACGCTGGGCTGGCTGCCCGTTTCCGGGCGGTTTGATTTACTTTATGAAGTGAAAACCGTCACTGGATTCGCC
CTGATCGATGCCTGGCTTTCCGATTCGCCATGGCGTGATGAAATGATGGTAAGCGCCATGCGTCATATGGTGTTGCCAGT
GATCACGCTGGCAGTCGCGCCAACAACAGAAGTGATACGTCTGATGCGCATTAGCACCATCGAAGTATTCGATCAAAACT
ACATCAAAGCGGCAGCAACACGCGGGCTTTCGCGATTTACTATTTTGCGCCGCCATGTTTTGCATAACGCCCTGCCGCCA
GTAATCCCACGTTTAGGTTTGCAATTTTCCACTATGCTGACACTGGCGATGATCACTGAAATGGTTTTTAGCTGGCCTGG
TTTAGGTCGCTGGCTAATCAACGCTATTCGTCAGCAAGATTACGCGGCGATTTCTGCCGGTGTAATGGTGTGTGGTTCGC
TGGTAATTATTGTTAACGTGATATCTGATATTTTGGGTGCAATGGCTAACCCGCTTAAACATAAGGAATTTTATGCCTTA
CGATAG

Upstream 100 bases:

>100_bases
AGGCTTACCGCTACGATATTAAAGGACTAGTGTTAAGCCCTTTTGGTAATGCTTCATTTGCCGGGGTTTATCGTGAAAAA
GCGAAAGAGGTGAAAAAACC

Downstream 100 bases:

>100_bases
CGTATACAGCGAAAAGCGCCCGCCTGGTACGCTGCGTACAGCCTGGCGCAAATTTTATGCTGATACTTCCGCAATGGTCG
GTCTGTACGGTTGTGCAGGC

Product: antimicrobial peptide ABC transporter permease

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIIFTLRRILLLLVTLFFLTFVGFSLNYFTPHAPLQGASLWNAWVFWFDGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALIVGIPIGMVAGIMRGKWQDQLINALALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKTVTGFA
LIDAWLSDSPWRDEMMVSAMRHMVLPVITLAVAPTTEVIRLMRISTIEVFDQNYIKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEFYAL
R

Sequences:

>Translated_321_residues
MIIFTLRRILLLLVTLFFLTFVGFSLNYFTPHAPLQGASLWNAWVFWFDGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALIVGIPIGMVAGIMRGKWQDQLINALALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKTVTGFA
LIDAWLSDSPWRDEMMVSAMRHMVLPVITLAVAPTTEVIRLMRISTIEVFDQNYIKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEFYAL
R
>Mature_321_residues
MIIFTLRRILLLLVTLFFLTFVGFSLNYFTPHAPLQGASLWNAWVFWFDGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALIVGIPIGMVAGIMRGKWQDQLINALALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKTVTGFA
LIDAWLSDSPWRDEMMVSAMRHMVLPVITLAVAPTTEVIRLMRISTIEVFDQNYIKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEFYAL
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=92.8348909657321, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=34.8837209302326, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=27.299703264095, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787761, Length=235, Percent_Identity=37.8723404255319, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787497, Length=331, Percent_Identity=27.4924471299094, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789888, Length=345, Percent_Identity=28.695652173913, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788504, Length=261, Percent_Identity=24.1379310344828, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36020; Mature: 36020

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCHHCCHHHCCC
>Mature Secondary Structure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HHHHHHHHCCCHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]