Click here to switch to the map view.

The map label for this gene is eamA [H]

Identifier: 218548897

GI number: 218548897

Start: 1576299

End: 1577192

Strand: Direct

Name: eamA [H]

Synonym: EFER_1542

Alternate gene names: 218548897

Gene position: 1576299-1577192 (Clockwise)

Preceding gene: 218548895

Following gene: 218548901

Centisome position: 34.35

GC content: 48.32

Gene sequence:

>894_bases
ATGTCACGTAAAGATGGCTTATTGGCATTACTGGTTGTTGTCGTATGGGGGCTTAATTTCGTTGTGATCAAAGTAGGATT
ACACAACATGCCGCCACTTATGCTGGCAGGCTTACGTTTTATGCTGGTGGCGTTCCCGGCAATCTTTTTCGTTGCTCGTC
CAAAAGTTCCACTCAGTTTACTGCTTGGGTATGGCCTGACGATTAGTTTTGGTCAGTTTGCTTTTCTTTTTTGTGCGCTA
AAGTTCGGTATGCCTGCCGGACTGGCGTCGCTGGTGCTCCAGGCGCAAGCTTTTTTTACTATTGTGCTGGGGGCTTTTAC
TTTTGGCGAACGGTTGCAGAGTAAGCAGGTTGCCGGGATCGCGCTGGCAGTATTGGGGGTATTCGTGCTGATAGAGGGTA
GCCTTAATGGTCAGGAGGTTGCCATTCTCGGTTTTATGCTGACACTCGCAGCCGCGTTCTGCTGGGCATGTGGCAATATC
TTTAACAAGAAGATTATGTCGCATTCTTCACGCCCGGCGGTGATGTCGTTGGTAGTATGGAGTGCGCTAATTCCCATTCT
GCCATTTATGGTGGCCTCGGTAGTTTTCGATGGTTCAGCACAGATGCTCCATAGCCTGGTAACCATTGATATAACCACGG
TGTTGTCCCTTATTTATCTCGCTTTTGTCGCCACAATTGTAGGTTATGGTATATGGGGAACACTGCTTGGACGCTATGAA
ACATGGCGCGTGGCTCCCCTATCTTTGCTGGTGCCGGTGGTAGGGTTACTCAGTGCGGTTATTCTGCTTGATGAAACACT
CTCATTAATGCAGCTATTCGGCGCGTTATTAATTATGGCGGGATTGTATATCAACGTGTTTGGTTTGCGATTGCGTAAAA
CGGTACGGGCATGA

Upstream 100 bases:

>100_bases
GAGATTCTGATCGCCGGGTGAGAATTTATGCACTTTCCATGGATGATAATTTCCGCTAACTTAGTTTCTTTACAAAAATT
TAATAATTCCCGGGGCGTTT

Downstream 100 bases:

>100_bases
TGATAATAAGGGGCTGCACATTATTGGCAAGTATGCATTATTCAGGCCGGAAGCGGCATGAAAGCCTAATCCGGCCTGAT
TCAATAGATTGCAAGAGTGA

Product: O-acetylserine/cysteine export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSRKDGLLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLSLLLGYGLTISFGQFAFLFCAL
KFGMPAGLASLVLQAQAFFTIVLGAFTFGERLQSKQVAGIALAVLGVFVLIEGSLNGQEVAILGFMLTLAAAFCWACGNI
FNKKIMSHSSRPAVMSLVVWSALIPILPFMVASVVFDGSAQMLHSLVTIDITTVLSLIYLAFVATIVGYGIWGTLLGRYE
TWRVAPLSLLVPVVGLLSAVILLDETLSLMQLFGALLIMAGLYINVFGLRLRKTVRA

Sequences:

>Translated_297_residues
MSRKDGLLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLSLLLGYGLTISFGQFAFLFCAL
KFGMPAGLASLVLQAQAFFTIVLGAFTFGERLQSKQVAGIALAVLGVFVLIEGSLNGQEVAILGFMLTLAAAFCWACGNI
FNKKIMSHSSRPAVMSLVVWSALIPILPFMVASVVFDGSAQMLHSLVTIDITTVLSLIYLAFVATIVGYGIWGTLLGRYE
TWRVAPLSLLVPVVGLLSAVILLDETLSLMQLFGALLIMAGLYINVFGLRLRKTVRA
>Mature_296_residues
SRKDGLLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLSLLLGYGLTISFGQFAFLFCALK
FGMPAGLASLVLQAQAFFTIVLGAFTFGERLQSKQVAGIALAVLGVFVLIEGSLNGQEVAILGFMLTLAAAFCWACGNIF
NKKIMSHSSRPAVMSLVVWSALIPILPFMVASVVFDGSAQMLHSLVTIDITTVLSLIYLAFVATIVGYGIWGTLLGRYET
WRVAPLSLLVPVVGLLSAVILLDETLSLMQLFGALLIMAGLYINVFGLRLRKTVRA

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=296, Percent_Identity=85.8108108108108, Blast_Score=494, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 32015; Mature: 31884

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKDGLLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLSL
CCCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLGYGLTISFGQFAFLFCALKFGMPAGLASLVLQAQAFFTIVLGAFTFGERLQSKQVAGI
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVLGVFVLIEGSLNGQEVAILGFMLTLAAAFCWACGNIFNKKIMSHSSRPAVMSLVVW
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SALIPILPFMVASVVFDGSAQMLHSLVTIDITTVLSLIYLAFVATIVGYGIWGTLLGRYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TWRVAPLSLLVPVVGLLSAVILLDETLSLMQLFGALLIMAGLYINVFGLRLRKTVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRKDGLLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLSL
CCCHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LLGYGLTISFGQFAFLFCALKFGMPAGLASLVLQAQAFFTIVLGAFTFGERLQSKQVAGI
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAVLGVFVLIEGSLNGQEVAILGFMLTLAAAFCWACGNIFNKKIMSHSSRPAVMSLVVW
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SALIPILPFMVASVVFDGSAQMLHSLVTIDITTVLSLIYLAFVATIVGYGIWGTLLGRYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TWRVAPLSLLVPVVGLLSAVILLDETLSLMQLFGALLIMAGLYINVFGLRLRKTVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]