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The map label for this gene is marC [H]

Identifier: 218548901

GI number: 218548901

Start: 1578613

End: 1579278

Strand: Direct

Name: marC [H]

Synonym: EFER_1546

Alternate gene names: 218548901

Gene position: 1578613-1579278 (Clockwise)

Preceding gene: 218548897

Following gene: 218548904

Centisome position: 34.4

GC content: 49.4

Gene sequence:

>666_bases
ATGATGGATTTGTTTAAGGCGATTGGTCTGGGGCTGGTGGTGTTGTTGCCGCTGGCAAACCCATTGACAACCGTGGCGCT
GTTTTTGGGACTGGCAGGCAATATGAACAGTGCCGAACGTAACCGCCAGTCGCTAATGGCTTCGGTATATGTTTTTGCCA
TTATGATGGTGGCGTATTACGCCGGACAGTTGGTGATGAATACCTTTGGTATTTCGATTCCCGGTTTACGTATTGCCGGG
GGACTCATTGTCGCGTTCATCGGTTTCCGTATGTTGTTTCCTCATCAGAAGGCGATTGAAACGCCGGAGGCAAAAAGCAA
AACGGAGGAACTGGAAGATGAATCTTCAGCGAATATCGCCTTTGTTCCGCTGGCGATGCCAAGCACTGCCGGGCCTGGCA
CCATTGCAATGATTATCAGCTCGGCATCCACAGTACGCCAAAGTTCTGATTTCGCCAGTTGGGTGATTCTGGTTGCGCCA
CCGATTATTTTCTTCATTGTTGCATTGATTCTTTGGGGATGCCTGCGTAGCTCCGGGGCAATTATGCGCTGGGTTGGAAA
AGGGGGAATCGAGGCGATTTCTCGCCTGATGGGCTTCCTGCTGGTGTGTATGGGCGTACAGTTTATTATCAATGGCGTGT
TGGAAATTATTAAAACGTATCATTAA

Upstream 100 bases:

>100_bases
GTGAATGTTGGTTGCTACCTGTACTCTCAGACTTTTACGCATAAACATGTTTTCCCCGTATACTCACCCTAAATCACATA
CCACAGGATGAATGACGACG

Downstream 100 bases:

>100_bases
GAATAAAGCCGGATGCACGATCCGGCTTTATAACTCAGTGTTGTGGTTGTTCTTCCAGCACCACCGGCCAGCGACGAAAA
ATAATCACTGACCATACCAA

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPHQKAIETPEAKSKTEELEDESSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSDFASWVILVAP
PIIFFIVALILWGCLRSSGAIMRWVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH

Sequences:

>Translated_221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPHQKAIETPEAKSKTEELEDESSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSDFASWVILVAP
PIIFFIVALILWGCLRSSGAIMRWVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
>Mature_221_residues
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAG
GLIVAFIGFRMLFPHQKAIETPEAKSKTEELEDESSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSDFASWVILVAP
PIIFFIVALILWGCLRSSGAIMRWVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=92.3076923076923, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1787494, Length=199, Percent_Identity=31.6582914572864, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789842, Length=209, Percent_Identity=25.8373205741627, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23733; Mature: 23733

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPHQKAIETPEAKSKTEELEDESSANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRQSSDFASWVILVAPPIIFFIVALILWGCLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IMRWVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPHQKAIETPEAKSKTEELEDESSANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRQSSDFASWVILVAPPIIFFIVALILWGCLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IMRWVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIKTYH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA