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The map label for this gene is siaT [H]

Identifier: 218548887

GI number: 218548887

Start: 1565277

End: 1566635

Strand: Direct

Name: siaT [H]

Synonym: EFER_1532

Alternate gene names: 218548887

Gene position: 1565277-1566635 (Clockwise)

Preceding gene: 218548886

Following gene: 218548888

Centisome position: 34.11

GC content: 44.67

Gene sequence:

>1359_bases
GTGTTTGTTAATGGTGGTGACGTCACTGTCATTTATCTTGCAGGGATGTCGGGAGAAAACTGCTGTCGTTCAGGAGGAAA
CATGTTAATAGCCGTCATTATATTTGTGGTATTACTTTGTATAGGTATGCCTGTAGGAATGGTTATTGCTATCTCCAGCC
TGAGTTATTTTTTTACCGCCGATTTTTTACCCATCGGTATAGCCTTTCAAAAATTTTCTGCACCAACACAATCATTTCCC
ATTCTGGCAACGCCACTCTTTTTATTAGTCGGCAACTTACTCAATAAATCGGGGGTAACCGGACGTTTGCTTGATTTTGC
TCGTGTGATATCTGGCTGGATGATTGGTGGACTGGCACAAATCAACGTATTACTGGCGTGTCTGTTGGGGGGCGTTTCGG
GGTCAGCAACGGCAGACGCCGCGATGCAGGCGAGGGTACTTGGTTTACCCATGGTAGCCAGGGGTTATCCGAAAGCATTT
AGTGCTGTAGTTATCGCCTTTAGTTCGCTAATTACTGCCACTATCCCGCCCAGTATTTTGATGATCCTGTATGGTTTTGT
AGGCAACGTCTCCATCGGCAAATTGTTTATGGCGGGTATTTTTCCTGGGCTACTGTTAACAGCAATACTGATGCTGACGA
ATTATCTTCTGGCGCGAAAAATGAATATCAAGCCAGAGACGGCTTCGTTGCCTGGTCGCCAGGAAGTGTGGCGTAGTTTT
AAAGAGAGTTTTTGGGCACTGATGTTTCCGGTGGTATTGATTGTCGTAATTCGCCTGGGGATTTTCACTACTACAGAAGC
TGGCGCGTTTATTGTCTTGTACTCGTTTATTATTGGTCGCTACATCTATAAGGCACTGGATAACGCAGTGTTGTGGGAAG
TCCTGAAAGAAACCATTAATGATGTCGGCGTTGTAATGCTGTTAATTATGTCGGCAGCCATTCTCGGCCATATCACCATT
CTGGACCAGATCCCGCAACAACTTGCAGAAACGATCCTTGCTTTCACAGAGAATAAATATGGCATCCTGTTTTTACTCCT
TACGCTAATAGCGGTTGCAGGGATGTTATTTGATGGCAGTGTGATTATTCTGCTATTAACGCCCATTTTGCTCCCTATTG
CCATTGAGGCTGGATTTGATCCTATCCATTTCGGCATGATTTTTGTGGTACTGACTCTGCTGGGTGCCAATACTCCACCG
GTTGGCATATGTATGTACACCGTCTGTGGCATTTTAAACTGCAGCTCTGTCGCGTTTGTTCGCGCGTCGCTCCCTTATTT
AATCGCATTTTTATCTTTCATTATTCTGTTGGTGATATTTCCGCAGATCGCGTTGTTTTTACCTTCGCTATTGATGTAA

Upstream 100 bases:

>100_bases
GCGTCTGGTACGGTTTTAACTTCACCTGGACGACACACAACCAGGTTCTGCCCGTTACTGAAATATCACTTGCCTGGCTG
AACAGTGCTGTGCCAACGGG

Downstream 100 bases:

>100_bases
GGCCAGAACTCACCGCTACGCTATTCCTTGCGGATAAGTAGCGCTTTTTTATTCACACTATGATTGGAATTAACAGGTCT
TCTTATGGAAAACAGACTAT

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MFVNGGDVTVIYLAGMSGENCCRSGGNMLIAVIIFVVLLCIGMPVGMVIAISSLSYFFTADFLPIGIAFQKFSAPTQSFP
ILATPLFLLVGNLLNKSGVTGRLLDFARVISGWMIGGLAQINVLLACLLGGVSGSATADAAMQARVLGLPMVARGYPKAF
SAVVIAFSSLITATIPPSILMILYGFVGNVSIGKLFMAGIFPGLLLTAILMLTNYLLARKMNIKPETASLPGRQEVWRSF
KESFWALMFPVVLIVVIRLGIFTTTEAGAFIVLYSFIIGRYIYKALDNAVLWEVLKETINDVGVVMLLIMSAAILGHITI
LDQIPQQLAETILAFTENKYGILFLLLTLIAVAGMLFDGSVIILLLTPILLPIAIEAGFDPIHFGMIFVVLTLLGANTPP
VGICMYTVCGILNCSSVAFVRASLPYLIAFLSFIILLVIFPQIALFLPSLLM

Sequences:

>Translated_452_residues
MFVNGGDVTVIYLAGMSGENCCRSGGNMLIAVIIFVVLLCIGMPVGMVIAISSLSYFFTADFLPIGIAFQKFSAPTQSFP
ILATPLFLLVGNLLNKSGVTGRLLDFARVISGWMIGGLAQINVLLACLLGGVSGSATADAAMQARVLGLPMVARGYPKAF
SAVVIAFSSLITATIPPSILMILYGFVGNVSIGKLFMAGIFPGLLLTAILMLTNYLLARKMNIKPETASLPGRQEVWRSF
KESFWALMFPVVLIVVIRLGIFTTTEAGAFIVLYSFIIGRYIYKALDNAVLWEVLKETINDVGVVMLLIMSAAILGHITI
LDQIPQQLAETILAFTENKYGILFLLLTLIAVAGMLFDGSVIILLLTPILLPIAIEAGFDPIHFGMIFVVLTLLGANTPP
VGICMYTVCGILNCSSVAFVRASLPYLIAFLSFIILLVIFPQIALFLPSLLM
>Mature_452_residues
MFVNGGDVTVIYLAGMSGENCCRSGGNMLIAVIIFVVLLCIGMPVGMVIAISSLSYFFTADFLPIGIAFQKFSAPTQSFP
ILATPLFLLVGNLLNKSGVTGRLLDFARVISGWMIGGLAQINVLLACLLGGVSGSATADAAMQARVLGLPMVARGYPKAF
SAVVIAFSSLITATIPPSILMILYGFVGNVSIGKLFMAGIFPGLLLTAILMLTNYLLARKMNIKPETASLPGRQEVWRSF
KESFWALMFPVVLIVVIRLGIFTTTEAGAFIVLYSFIIGRYIYKALDNAVLWEVLKETINDVGVVMLLIMSAAILGHITI
LDQIPQQLAETILAFTENKYGILFLLLTLIAVAGMLFDGSVIILLLTPILLPIAIEAGFDPIHFGMIFVVLTLLGANTPP
VGICMYTVCGILNCSSVAFVRASLPYLIAFLSFIILLVIFPQIALFLPSLLM

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=401, Percent_Identity=33.9152119700748, Blast_Score=197, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48530; Mature: 48530

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVNGGDVTVIYLAGMSGENCCRSGGNMLIAVIIFVVLLCIGMPVGMVIAISSLSYFFTA
CEECCCCEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DFLPIGIAFQKFSAPTQSFPILATPLFLLVGNLLNKSGVTGRLLDFARVISGWMIGGLAQ
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INVLLACLLGGVSGSATADAAMQARVLGLPMVARGYPKAFSAVVIAFSSLITATIPPSIL
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
MILYGFVGNVSIGKLFMAGIFPGLLLTAILMLTNYLLARKMNIKPETASLPGRQEVWRSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KESFWALMFPVVLIVVIRLGIFTTTEAGAFIVLYSFIIGRYIYKALDNAVLWEVLKETIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVGVVMLLIMSAAILGHITILDQIPQQLAETILAFTENKYGILFLLLTLIAVAGMLFDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCH
VIILLLTPILLPIAIEAGFDPIHFGMIFVVLTLLGANTPPVGICMYTVCGILNCSSVAFV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
RASLPYLIAFLSFIILLVIFPQIALFLPSLLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFVNGGDVTVIYLAGMSGENCCRSGGNMLIAVIIFVVLLCIGMPVGMVIAISSLSYFFTA
CEECCCCEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DFLPIGIAFQKFSAPTQSFPILATPLFLLVGNLLNKSGVTGRLLDFARVISGWMIGGLAQ
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INVLLACLLGGVSGSATADAAMQARVLGLPMVARGYPKAFSAVVIAFSSLITATIPPSIL
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHH
MILYGFVGNVSIGKLFMAGIFPGLLLTAILMLTNYLLARKMNIKPETASLPGRQEVWRSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KESFWALMFPVVLIVVIRLGIFTTTEAGAFIVLYSFIIGRYIYKALDNAVLWEVLKETIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVGVVMLLIMSAAILGHITILDQIPQQLAETILAFTENKYGILFLLLTLIAVAGMLFDGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCH
VIILLLTPILLPIAIEAGFDPIHFGMIFVVLTLLGANTPPVGICMYTVCGILNCSSVAFV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
RASLPYLIAFLSFIILLVIFPQIALFLPSLLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]