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The map label for this gene is cheW [H]

Identifier: 218548505

GI number: 218548505

Start: 1175748

End: 1176242

Strand: Direct

Name: cheW [H]

Synonym: EFER_1134

Alternate gene names: 218548505

Gene position: 1175748-1176242 (Clockwise)

Preceding gene: 218548504

Following gene: 218548506

Centisome position: 25.62

GC content: 49.49

Gene sequence:

>495_bases
ATGAATACAACGAACAAATTAGCCGGCGAGCCAACGGGTCAGGAATTTCTGGTTTTTACGTTGGGGGAAGAAGAGTACGG
CATTGATATCCTTAAAGTTCAGGAGATTCGTGGTTACGACCAGGTAACGCGTATCGCCAATACTCCAGCCTTTATTAAAG
GTGTCACTAACCTGCGTGGTGTTATCGTGCCGATTGTCGATCTGCGGGTTAAGTTCTGTCAGGGCGATGTGGATTATGAC
GATAATACCGTGGTGATCGTTCTTAACCTTGGGCAACGGGTCGTTGGCATTGTTGTCGATGGTGTGTCGGATGTGCTCTC
ACTGACCGCTGAACAAATTCGCCCGGCACCAGAATTTGCTGTAACGCTGGCGACAGAATACCTGACTGGACTCGGAGCGC
TGGGTGATCGCATGTTGATTCTGGTGAATATCGAAAAACTGCTGAATAGTGAGGAAATGGCGCTTCTGGATAGCGCGACT
GCGGAAGTGGCGTAA

Upstream 100 bases:

>100_bases
GATGGCAGCGTCGCACTGATTGTCGATGTCTCGGCACTGCAAGGGTTAAATCGCGAACAACGTATGGCGGGTAACGCCGC
CTGAACAGGACGATAAAAAC

Downstream 100 bases:

>100_bases
CACTTAATATCACGGCCAGCACTCTGTTTATCGGGTGCTGGCATGTGATCAACTTCACATAAGAATGAATATATCCTCTC
AGTATACTTTGTTATCGCCC

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MNTTNKLAGEPTGQEFLVFTLGEEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCQGDVDYD
DNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLATEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAT
AEVA

Sequences:

>Translated_164_residues
MNTTNKLAGEPTGQEFLVFTLGEEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCQGDVDYD
DNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLATEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAT
AEVA
>Mature_164_residues
MNTTNKLAGEPTGQEFLVFTLGEEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCQGDVDYD
DNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLATEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSAT
AEVA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=164, Percent_Identity=91.4634146341463, Blast_Score=299, Evalue=6e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17767; Mature: 17767

Theoretical pI: Translated: 4.03; Mature: 4.03

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTNKLAGEPTGQEFLVFTLGEEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRG
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEHHHCCHHHHHHHCCCCHHHHHHHCCCE
VIVPIVDLRVKFCQGDVDYDDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFA
EEEEHHHHEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCCHHH
VTLATEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSATAEVA
HHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MNTTNKLAGEPTGQEFLVFTLGEEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRG
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEHHHCCHHHHHHHCCCCHHHHHHHCCCE
VIVPIVDLRVKFCQGDVDYDDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFA
EEEEHHHHEEEEECCCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHCCCCCHHH
VTLATEYLTGLGALGDRMLILVNIEKLLNSEEMALLDSATAEVA
HHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]