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The map label for this gene is cheA [H]

Identifier: 218548504

GI number: 218548504

Start: 1173716

End: 1175731

Strand: Direct

Name: cheA [H]

Synonym: EFER_1133

Alternate gene names: 218548504

Gene position: 1173716-1175731 (Clockwise)

Preceding gene: 218548503

Following gene: 218548505

Centisome position: 25.58

GC content: 52.18

Gene sequence:

>2016_bases
GTGTTTTATCACAGCCTGAGGCTGTTCCCACATCGCCACCAGCCAATTCGAGGTGACCGCGTGAGTATGGAATTAAGCGA
TTTTTATCAAACATTTTTTGATGAGGCTGACGAGCTGTTAGCTGATATGGAGCAGCATTTGCTCGATCTACAACCAGCAG
CACCAGACGCCGAACAATTGAACGCCATTTTTCGTGCTGCCCATTCCATCAAAGGTGGGGCGGGAACATTTGGTTTTACG
ATCCTGCAGGAAACCACTCATCTTATGGAAAACCTGCTGGACGAGGCCCGGCGCGGTGAATTGCAGTTGAACACCGACAT
TATCAACCTGTTTTTGGAAACGAAAGACATTATGCAAGAACAGCTAGACGCCTACAAAAATGCGGAACAGCCGGATGCCG
AAAGTTTTGACTACATCTGTCAGGCGTTGCGACAACTGGCGCTGGAAGCAAAAGGCGAAGCCGTACCTGCCGACGATAGC
CACAGTAAATTACAGGCGGTTAAAGAGGCTGCACCGTCTACAAACGCCAATGGCAAGTTGCGCATTGTGTTGTCACGCCT
GAAAAGTAAAGAAGTTGATTTACTGGAAGCGGAACTGCGCAATCTGGCGACCTTAAGCGAGGTAGTAAAAGGCGAAGATT
CACTGGCAGCGACGCTGGAGGGCGATATCGCGCAGGATGACATTGTGGCGGTGCTCTGTTTTGTGATCGAAGAAGATCAG
ATTCATTTTGAAAACGTCACGCAACAGCCTGTGGCCCCGGTGGCAAAAGCCCCCGTCAGCGAACCACCGGTACACCGTGC
AGAACGAGAAAAACCGGCCCGCGCCAGTGAATCCACCAGCATTCGTGTGGCGGTTGAGAAAGTGGATCAACTGATAAACC
TTGTCGGGGAGCTGGTAATTACCCAGTCGATGCTGGCACAACGGTCGAACGAACTTGATCCGGTTAAACATGGCGAACTG
ATCACCAGCATGGGGCAGTTGCAACGTAATGCACGTGACTTGCAAGAGTCGGTCATGTCGATCCGCATGATGCCCATGGA
ATATGTGTTTAGCCGTTTCCCGCGACTGGTCCGTGACCTTGCAGGAAAACTGGGTAAACAGGTTGAACTGACGCTGGTGG
GTAGCTCCACAGAACTTGATAAGAGCCTGATAGAGCGAATTATTGATCCACTGACGCATCTGGTGCGCAACAGCCTTGAC
CATGGTATTGAACTGCCAGAAAAACGACTGGCCAGTGGTAAAAACAGCGTGGGTAACTTGATTCTTTCCGCTGAACATCA
GGGTGGCAATATCTGTATTGAAGTCACTGATGATGGAGCAGGGCTGAACCGTGAGCGTATCCTGGCGAAAGCGATTTCTC
AGGGGATGGCGGTCAGTGACAACATGACCGATGACGAAGTGGCAATGTTAATTTTTGCGCCAGGCTTCTCCACTGCCGAA
CAGGTAACCGACGTGTCCGGGCGTGGCGTTGGTATGGATGTGGTGAAACGGAACATCCAGGAAATGGGCGGGCATGTTGA
AATTCAGTCGAAGCAGGGGGCAGGAACCACGATTCGTATTTTGCTACCACTGACACTGGCGATCCTTGATGGCATGTCAG
TACGCGTGGCCGACGAGGTATTCATCCTGCCGCTGAATGCGGTGATGGAATCACTCCAGCCACGAGAAGCCGATCTACAT
CCACTGGCGGGCGGAGAACGTGTACTGGAAGTCCGTGGTGAATACTTACCGCTGGTGGAATTGTGGAAAGTTTTTGATGT
TGCGGGAGCGAAAACGGAAGCGACGCAGGGGATTGTGGTGATCCTGCAAAGCGGTAGCCGTCGCTATGCGCTGCTGGTGG
ATCAATTGATCGGTCAGCACCAGGTGGTGGTGAAAAACCTGGAAAGCAATTACCGCAAAGTGCCTGGGATCTCTGCCGCG
ACCATTCTGGGGGATGGCAGCGTCGCACTGATTGTCGATGTCTCGGCACTGCAAGGGTTAAATCGCGAACAACGTATGGC
GGGTAACGCCGCCTGA

Upstream 100 bases:

>100_bases
AATGATGCCATTAACCGCCGTATAAGCCTGCTGGTACTTAATAAACAGACCGAGCAGGCAATTTTGCACGAAAACGCTGA
AAGCCAGAACGAGCCGGTAA

Downstream 100 bases:

>100_bases
ACAGGACGATAAAAACATGAATACAACGAACAAATTAGCCGGCGAGCCAACGGGTCAGGAATTTCTGGTTTTTACGTTGG
GGGAAGAAGAGTACGGCATT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MFYHSLRLFPHRHQPIRGDRVSMELSDFYQTFFDEADELLADMEQHLLDLQPAAPDAEQLNAIFRAAHSIKGGAGTFGFT
ILQETTHLMENLLDEARRGELQLNTDIINLFLETKDIMQEQLDAYKNAEQPDAESFDYICQALRQLALEAKGEAVPADDS
HSKLQAVKEAAPSTNANGKLRIVLSRLKSKEVDLLEAELRNLATLSEVVKGEDSLAATLEGDIAQDDIVAVLCFVIEEDQ
IHFENVTQQPVAPVAKAPVSEPPVHRAEREKPARASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVKHGEL
ITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLD
HGIELPEKRLASGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVSDNMTDDEVAMLIFAPGFSTAE
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGAGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLH
PLAGGERVLEVRGEYLPLVELWKVFDVAGAKTEATQGIVVILQSGSRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAA
TILGDGSVALIVDVSALQGLNREQRMAGNAA

Sequences:

>Translated_671_residues
MFYHSLRLFPHRHQPIRGDRVSMELSDFYQTFFDEADELLADMEQHLLDLQPAAPDAEQLNAIFRAAHSIKGGAGTFGFT
ILQETTHLMENLLDEARRGELQLNTDIINLFLETKDIMQEQLDAYKNAEQPDAESFDYICQALRQLALEAKGEAVPADDS
HSKLQAVKEAAPSTNANGKLRIVLSRLKSKEVDLLEAELRNLATLSEVVKGEDSLAATLEGDIAQDDIVAVLCFVIEEDQ
IHFENVTQQPVAPVAKAPVSEPPVHRAEREKPARASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVKHGEL
ITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLD
HGIELPEKRLASGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVSDNMTDDEVAMLIFAPGFSTAE
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGAGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLH
PLAGGERVLEVRGEYLPLVELWKVFDVAGAKTEATQGIVVILQSGSRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAA
TILGDGSVALIVDVSALQGLNREQRMAGNAA
>Mature_671_residues
MFYHSLRLFPHRHQPIRGDRVSMELSDFYQTFFDEADELLADMEQHLLDLQPAAPDAEQLNAIFRAAHSIKGGAGTFGFT
ILQETTHLMENLLDEARRGELQLNTDIINLFLETKDIMQEQLDAYKNAEQPDAESFDYICQALRQLALEAKGEAVPADDS
HSKLQAVKEAAPSTNANGKLRIVLSRLKSKEVDLLEAELRNLATLSEVVKGEDSLAATLEGDIAQDDIVAVLCFVIEEDQ
IHFENVTQQPVAPVAKAPVSEPPVHRAEREKPARASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVKHGEL
ITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLD
HGIELPEKRLASGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVSDNMTDDEVAMLIFAPGFSTAE
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGAGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLH
PLAGGERVLEVRGEYLPLVELWKVFDVAGAKTEATQGIVVILQSGSRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAA
TILGDGSVALIVDVSALQGLNREQRMAGNAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=657, Percent_Identity=85.0837138508371, Blast_Score=1119, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73556; Mature: 73556

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYHSLRLFPHRHQPIRGDRVSMELSDFYQTFFDEADELLADMEQHLLDLQPAAPDAEQL
CCCCCEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
NAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGELQLNTDIINLFLETKDIMQE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHH
QLDAYKNAEQPDAESFDYICQALRQLALEAKGEAVPADDSHSKLQAVKEAAPSTNANGKL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
RIVLSRLKSKEVDLLEAELRNLATLSEVVKGEDSLAATLEGDIAQDDIVAVLCFVIEEDQ
EHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHCCCC
IHFENVTQQPVAPVAKAPVSEPPVHRAEREKPARASESTSIRVAVEKVDQLINLVGELVI
CHHHCCCCCCCCHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
TQSMLAQRSNELDPVKHGELITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLASGKNSVGNL
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCE
ILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVSDNMTDDEVAMLIFAPGFSTAE
EEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHH
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGAGTTIRILLPLTLAILDGMSVRVADEV
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCEEEECCE
FILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPLVELWKVFDVAGAKTEATQGIVV
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
ILQSGSRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGL
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCC
NREQRMAGNAA
CHHHHHCCCCC
>Mature Secondary Structure
MFYHSLRLFPHRHQPIRGDRVSMELSDFYQTFFDEADELLADMEQHLLDLQPAAPDAEQL
CCCCCEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
NAIFRAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGELQLNTDIINLFLETKDIMQE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHH
QLDAYKNAEQPDAESFDYICQALRQLALEAKGEAVPADDSHSKLQAVKEAAPSTNANGKL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEE
RIVLSRLKSKEVDLLEAELRNLATLSEVVKGEDSLAATLEGDIAQDDIVAVLCFVIEEDQ
EHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHHCCCC
IHFENVTQQPVAPVAKAPVSEPPVHRAEREKPARASESTSIRVAVEKVDQLINLVGELVI
CHHHCCCCCCCCHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
TQSMLAQRSNELDPVKHGELITSMGQLQRNARDLQESVMSIRMMPMEYVFSRFPRLVRDL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLASGKNSVGNL
HHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCE
ILSAEHQGGNICIEVTDDGAGLNRERILAKAISQGMAVSDNMTDDEVAMLIFAPGFSTAE
EEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHH
QVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGAGTTIRILLPLTLAILDGMSVRVADEV
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCEEEECCE
FILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPLVELWKVFDVAGAKTEATQGIVV
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEE
ILQSGSRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQGL
EEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHCC
NREQRMAGNAA
CHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]