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The map label for this gene is eryB [H]

Identifier: 218547752

GI number: 218547752

Start: 347775

End: 349310

Strand: Reverse

Name: eryB [H]

Synonym: EFER_0337

Alternate gene names: 218547752

Gene position: 349310-347775 (Counterclockwise)

Preceding gene: 218547753

Following gene: 218547751

Centisome position: 7.61

GC content: 52.93

Gene sequence:

>1536_bases
ATGGAGTCAGCCATGAGTGAAAAGATTCTTGATCTGTTTGTTATTGGCGGTGGCATCAACGGTGCGGGTATCGCACGTGA
TGCCGCCGGGCGCGGGCTATCTGTCGCCATGTGTGAAAAGGACGATCTGGCCCAGGGCACATCTTCTCGTTCCGGCAAGC
TGGTACATGGCGGGTTACGTTATCTGGAATATTATGAATTTCGTCTGGTCCGTGAAGCGCTTATCGAACGCGAAGTGTTG
TTAAATGCGGCACCGCATATTGTCTGGCCGATGCGCTTTGTCCTTCCGCATAGCCCAGGCGATCGTCCGGCATGGCTTGT
CCGTATGGGGCTTTACTTATATGACCACCTGGGTGGGCGTAAAAAACTTCCCGGTACACGGATCCTCGATTTACATCAAG
ATCCGGAAGGCGCGCCAATCAAAAATGCGTATCGCAAAGGGTTTGAGTATTCCGACTGCTGGGTAGATGATGCGCGACTG
GTCTCACTGAACGCACTGGACGCCGCCGAGCACGGAGCCACTATTCTCACCCGTACGCGTTGTATCTCCGCCCACCGCGC
TGCCGACGCATGGGTTATCACATTACAAAACACTCAAACTGGTGAACAACAGACGCTGCGTGCCAAAGCGCTGGTCAATG
CGGCTGGCCCCTGGGTTCTGGAGATAATCAACCAGGTGACCCAAACCCGCAGCAGCCGCAACGTTCGTCTGGTGAAAGGT
TCACACATCATCGTGCCGAAATTCTGGGAAGGTCAGCAAGCCTACCTGATGCAAAATAACGATAAACGCGTCATTTTTAT
TAACCCGTATGAAGGCGATAAGGCACTGATTGGCACCACCGATATTCCCTGGGAAGGTGATGCTGACTCCGTGACTGCCG
ATGACAGCGAGCAGCAATATCTGCTGGATGTGATTAATCGTTATTTCAAAATTCAGCTCTGCGCCAGTGATGTCATCACC
CGTTTTTCCGGGGTCAGGCCACTGTTTGATGATGGCAAAGGTAACCCTTCGGCAGTAACGCGCGACTATGTGTTTGAGCT
TGATGAGCAACAACAATTGCCGTTGCTCCATGTGTTTGGCGGGAAAATCACCACCTTCCGTAAACTGGCGGAACACGCCC
TGCAAAAACTGAAACCCTTTTTTCCGCACATGGGTGCCGACTGGACGCGCACAGCAGTGCTGCCCGGCGGAGAAATAGCC
GATGCCGATTTTGAAACTTTCCTGCAATCCATGAAAAGCCGTTACAACTGGTTACCTCAGCATCTGTGTAAGCATTACGC
CCGTCTGTATGGCGCGCGGATGCCACAGCTGTTAGGGGAAGCTACGAGCCTTGAGGAGTTAGGCCTGCACTTCGGCGGTC
TGTTTTATGAAGCCGAAGCGCGTTACCTCATCGAAAAAGAGTGGGCGAAACAGGCGGATGATATTCTTTGGCGACGGACC
AAGCATGGTCTTCACCTTAGCGACGATGAGCAACGGGCCTTTAGCGGATGGTTTACCGCCACCAGACATTCGCCACTACA
GGCTAAAGCCAGCTAA

Upstream 100 bases:

>100_bases
GTTACCAGCATTTATTTAACTGCTACCAGCAACTTCGCCGCGAACTGCCACCAGCCTGGAATGTATTAAATCCCCCGTCA
GCCGCATGTTAATTTGATTT

Downstream 100 bases:

>100_bases
GGAGAGAATAATGGCGCTTTCTTTGTCTTTAAATACCAATCCATTGGTTAACCGGATTGCGACGCCGGAAGATCTGCTTA
ATACCATTGCCCGGCAAATT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MESAMSEKILDLFVIGGGINGAGIARDAAGRGLSVAMCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVL
LNAAPHIVWPMRFVLPHSPGDRPAWLVRMGLYLYDHLGGRKKLPGTRILDLHQDPEGAPIKNAYRKGFEYSDCWVDDARL
VSLNALDAAEHGATILTRTRCISAHRAADAWVITLQNTQTGEQQTLRAKALVNAAGPWVLEIINQVTQTRSSRNVRLVKG
SHIIVPKFWEGQQAYLMQNNDKRVIFINPYEGDKALIGTTDIPWEGDADSVTADDSEQQYLLDVINRYFKIQLCASDVIT
RFSGVRPLFDDGKGNPSAVTRDYVFELDEQQQLPLLHVFGGKITTFRKLAEHALQKLKPFFPHMGADWTRTAVLPGGEIA
DADFETFLQSMKSRYNWLPQHLCKHYARLYGARMPQLLGEATSLEELGLHFGGLFYEAEARYLIEKEWAKQADDILWRRT
KHGLHLSDDEQRAFSGWFTATRHSPLQAKAS

Sequences:

>Translated_511_residues
MESAMSEKILDLFVIGGGINGAGIARDAAGRGLSVAMCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVL
LNAAPHIVWPMRFVLPHSPGDRPAWLVRMGLYLYDHLGGRKKLPGTRILDLHQDPEGAPIKNAYRKGFEYSDCWVDDARL
VSLNALDAAEHGATILTRTRCISAHRAADAWVITLQNTQTGEQQTLRAKALVNAAGPWVLEIINQVTQTRSSRNVRLVKG
SHIIVPKFWEGQQAYLMQNNDKRVIFINPYEGDKALIGTTDIPWEGDADSVTADDSEQQYLLDVINRYFKIQLCASDVIT
RFSGVRPLFDDGKGNPSAVTRDYVFELDEQQQLPLLHVFGGKITTFRKLAEHALQKLKPFFPHMGADWTRTAVLPGGEIA
DADFETFLQSMKSRYNWLPQHLCKHYARLYGARMPQLLGEATSLEELGLHFGGLFYEAEARYLIEKEWAKQADDILWRRT
KHGLHLSDDEQRAFSGWFTATRHSPLQAKAS
>Mature_511_residues
MESAMSEKILDLFVIGGGINGAGIARDAAGRGLSVAMCEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVL
LNAAPHIVWPMRFVLPHSPGDRPAWLVRMGLYLYDHLGGRKKLPGTRILDLHQDPEGAPIKNAYRKGFEYSDCWVDDARL
VSLNALDAAEHGATILTRTRCISAHRAADAWVITLQNTQTGEQQTLRAKALVNAAGPWVLEIINQVTQTRSSRNVRLVKG
SHIIVPKFWEGQQAYLMQNNDKRVIFINPYEGDKALIGTTDIPWEGDADSVTADDSEQQYLLDVINRYFKIQLCASDVIT
RFSGVRPLFDDGKGNPSAVTRDYVFELDEQQQLPLLHVFGGKITTFRKLAEHALQKLKPFFPHMGADWTRTAVLPGGEIA
DADFETFLQSMKSRYNWLPQHLCKHYARLYGARMPQLLGEATSLEELGLHFGGLFYEAEARYLIEKEWAKQADDILWRRT
KHGLHLSDDEQRAFSGWFTATRHSPLQAKAS

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=501, Percent_Identity=29.940119760479, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI285002231, Length=501, Percent_Identity=29.940119760479, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=50, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788574, Length=482, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534726, Length=516, Percent_Identity=31.2015503875969, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17509253, Length=499, Percent_Identity=30.4609218436874, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6322036, Length=528, Percent_Identity=28.7878787878788, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI161077125, Length=507, Percent_Identity=30.9664694280079, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24653942, Length=507, Percent_Identity=30.9664694280079, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24653944, Length=507, Percent_Identity=30.9664694280079, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI20130025, Length=507, Percent_Identity=30.9664694280079, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24586295, Length=383, Percent_Identity=28.9817232375979, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19921278, Length=487, Percent_Identity=22.7926078028747, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57577; Mature: 57577

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESAMSEKILDLFVIGGGINGAGIARDAAGRGLSVAMCEKDDLAQGTSSRSGKLVHGGLR
CCHHHHHHHEEEEEECCCCCCCCCCHHCCCCCCEEEEECCHHHCCCCCCCCCCEEEHHHH
YLEYYEFRLVREALIEREVLLNAAPHIVWPMRFVLPHSPGDRPAWLVRMGLYLYDHLGGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHCCCC
KKLPGTRILDLHQDPEGAPIKNAYRKGFEYSDCWVDDARLVSLNALDAAEHGATILTRTR
CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHCCCEEEHHHH
CISAHRAADAWVITLQNTQTGEQQTLRAKALVNAAGPWVLEIINQVTQTRSSRNVRLVKG
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEC
SHIIVPKFWEGQQAYLMQNNDKRVIFINPYEGDKALIGTTDIPWEGDADSVTADDSEQQY
CEEEEECCCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
LLDVINRYFKIQLCASDVITRFSGVRPLFDDGKGNPSAVTRDYVFELDEQQQLPLLHVFG
HHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCEEEECC
GKITTFRKLAEHALQKLKPFFPHMGADWTRTAVLPGGEIADADFETFLQSMKSRYNWLPQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HLCKHYARLYGARMPQLLGEATSLEELGLHFGGLFYEAEARYLIEKEWAKQADDILWRRT
HHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
KHGLHLSDDEQRAFSGWFTATRHSPLQAKAS
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MESAMSEKILDLFVIGGGINGAGIARDAAGRGLSVAMCEKDDLAQGTSSRSGKLVHGGLR
CCHHHHHHHEEEEEECCCCCCCCCCHHCCCCCCEEEEECCHHHCCCCCCCCCCEEEHHHH
YLEYYEFRLVREALIEREVLLNAAPHIVWPMRFVLPHSPGDRPAWLVRMGLYLYDHLGGR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHCCCC
KKLPGTRILDLHQDPEGAPIKNAYRKGFEYSDCWVDDARLVSLNALDAAEHGATILTRTR
CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHCCCEEEHHHH
CISAHRAADAWVITLQNTQTGEQQTLRAKALVNAAGPWVLEIINQVTQTRSSRNVRLVKG
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEC
SHIIVPKFWEGQQAYLMQNNDKRVIFINPYEGDKALIGTTDIPWEGDADSVTADDSEQQY
CEEEEECCCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
LLDVINRYFKIQLCASDVITRFSGVRPLFDDGKGNPSAVTRDYVFELDEQQQLPLLHVFG
HHHHHHHHHEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCCEEEECC
GKITTFRKLAEHALQKLKPFFPHMGADWTRTAVLPGGEIADADFETFLQSMKSRYNWLPQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HLCKHYARLYGARMPQLLGEATSLEELGLHFGGLFYEAEARYLIEKEWAKQADDILWRRT
HHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHH
KHGLHLSDDEQRAFSGWFTATRHSPLQAKAS
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]