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The map label for this gene is eryA [H]

Identifier: 218547753

GI number: 218547753

Start: 349319

End: 350881

Strand: Reverse

Name: eryA [H]

Synonym: EFER_0338

Alternate gene names: 218547753

Gene position: 350881-349319 (Counterclockwise)

Preceding gene: 218547760

Following gene: 218547752

Centisome position: 7.65

GC content: 56.49

Gene sequence:

>1563_bases
ATGGATAATCGTGACATCATTCTTGGGCTGGACTCCGGCACTTCAGTCGTAAAGGCCGTGGCGTTTGATCTTGAGGGTGA
ACAAATAGAGTGCGCTTCCGTACGCAATAGCTATTCACGCAGTGCGGGCGGCGCAGCGCAACAGTCCATGGAACAGACCT
GGCAGGATGCCGTGGTGTCTATCCGCAAACTTGCTGAACGTGTGGAAAATCTGGCTGAGCGTGTGGTTGCGATTGCTGTC
ACCGGGCAAGGCGACGGCACCTGGCTGGTGGGCCACCAAAACCGCCCGGTCGATGACGCCTGGATTTGGCTGGACGCCCG
CGCCGCGCCTACCGTTGAGACTCTTTCGCGCTCACCGCTGGCGCGTGCACGCTTTGAAGCAACGGGAACAGGGTTAAATA
CCTGTCAGCAAAGTGCGCAGATGGCGCATATGGACCGCTTTTATCCGCAGTTGCTGGACAACAGCGAGGTGGCGCTCCAT
TGCAAAGACTGGCTGTATCTGAATTTAACGGGTATCCGGGCGACCGATCCTTCCGAAGCCAGTTTTACCTTTGGTAATTT
TCGCCACCAACGCTATGACGATCTGGTTATTGCGGCGCTGGGGCTTGAGCATCGTCACCATCTTCTGCCTGAGATTATCG
ACGGCAGTAACATCACCCACGCGTTAACCAAAGAGGCCGCGGCGCTTACCGGGCTACGCGCCGGGACGCCCGTCAGTCTG
GGTTATGTCGATATGGTGATGACGGCGCTGGGAGCAGGCGTACATACCGGCGAGGCAAATACCGCCTGTTCGATTGTCGG
CTCAACAGGCGTGCATCTTCGTAGCGTATCGACCGACAACGTGTGGCTTAACAGTGAGCAAACAGGGTATGTCATTCAAC
TGCCCTGCCCTGGTTATGTCACCCAGGTGCAAACCAATATGGCATCGACCCTTAATCTCGACTGGCTATTACATGTCGCC
AGTGAGCTGTTGGCAAGCTTTGGTTGCGAAGTCAGCCACGCCAGACTGGTCCAGCATCTTGATCGCTGGCTCAGTGAGGC
AAAACCCGGTGCCTTGCTGTATCACCCCTATATTTCCGAAGCCGGGGAACGTGGGCCTTTCGTCAATGCGAATGCGAGGG
CAAGTTTAGTTGGCCTGAGTTATAGCCACGGTTTTGCGGATCTGGTTCGCGCCGTCATTGAAGGGATCGGCTTTGCCGCA
CGGGATTGTTATCTGGCAATGGGTGAGCAATTGCCCGGCGAATTACGTCTTACCGGTGGCGCGATTCGTTCGCCACAGCT
TCGTCAGGTGCTATCAGCCTGCCTTGGCGTGCCAGTTCGCAGCAGCAAACGTGAAGAAGCGGGTGCCGCCGGAGCGGCAA
TGATGGCTGCCGTCGCTATCGGCGCGTATCCCTCCATGGAACAGTGCATTGCAACATGGGTAACACCGCTTCTCGATGCC
CCTGAACCCCCATCTTCCGCGCTGACTGACCGTTACCAGCATTTATTTAACTGCTACCAGCAACTTCGCCGCGAACTGCC
ACCAGCCTGGAATGTATTAAATCCCCCGTCAGCCGCATGTTAA

Upstream 100 bases:

>100_bases
TTGTGATAAATGTTAAGTAACGTTATTACTCAATAAAAGTTACACGTAATTAACAACTATTTTTGCAACCACTGCGGTCA
ACCTGATAACAGAGGCATCG

Downstream 100 bases:

>100_bases
TTTGATTTATGGAGTCAGCCATGAGTGAAAAGATTCTTGATCTGTTTGTTATTGGCGGTGGCATCAACGGTGCGGGTATC
GCACGTGATGCCGCCGGGCG

Product: erythritol kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MDNRDIILGLDSGTSVVKAVAFDLEGEQIECASVRNSYSRSAGGAAQQSMEQTWQDAVVSIRKLAERVENLAERVVAIAV
TGQGDGTWLVGHQNRPVDDAWIWLDARAAPTVETLSRSPLARARFEATGTGLNTCQQSAQMAHMDRFYPQLLDNSEVALH
CKDWLYLNLTGIRATDPSEASFTFGNFRHQRYDDLVIAALGLEHRHHLLPEIIDGSNITHALTKEAAALTGLRAGTPVSL
GYVDMVMTALGAGVHTGEANTACSIVGSTGVHLRSVSTDNVWLNSEQTGYVIQLPCPGYVTQVQTNMASTLNLDWLLHVA
SELLASFGCEVSHARLVQHLDRWLSEAKPGALLYHPYISEAGERGPFVNANARASLVGLSYSHGFADLVRAVIEGIGFAA
RDCYLAMGEQLPGELRLTGGAIRSPQLRQVLSACLGVPVRSSKREEAGAAGAAMMAAVAIGAYPSMEQCIATWVTPLLDA
PEPPSSALTDRYQHLFNCYQQLRRELPPAWNVLNPPSAAC

Sequences:

>Translated_520_residues
MDNRDIILGLDSGTSVVKAVAFDLEGEQIECASVRNSYSRSAGGAAQQSMEQTWQDAVVSIRKLAERVENLAERVVAIAV
TGQGDGTWLVGHQNRPVDDAWIWLDARAAPTVETLSRSPLARARFEATGTGLNTCQQSAQMAHMDRFYPQLLDNSEVALH
CKDWLYLNLTGIRATDPSEASFTFGNFRHQRYDDLVIAALGLEHRHHLLPEIIDGSNITHALTKEAAALTGLRAGTPVSL
GYVDMVMTALGAGVHTGEANTACSIVGSTGVHLRSVSTDNVWLNSEQTGYVIQLPCPGYVTQVQTNMASTLNLDWLLHVA
SELLASFGCEVSHARLVQHLDRWLSEAKPGALLYHPYISEAGERGPFVNANARASLVGLSYSHGFADLVRAVIEGIGFAA
RDCYLAMGEQLPGELRLTGGAIRSPQLRQVLSACLGVPVRSSKREEAGAAGAAMMAAVAIGAYPSMEQCIATWVTPLLDA
PEPPSSALTDRYQHLFNCYQQLRRELPPAWNVLNPPSAAC
>Mature_520_residues
MDNRDIILGLDSGTSVVKAVAFDLEGEQIECASVRNSYSRSAGGAAQQSMEQTWQDAVVSIRKLAERVENLAERVVAIAV
TGQGDGTWLVGHQNRPVDDAWIWLDARAAPTVETLSRSPLARARFEATGTGLNTCQQSAQMAHMDRFYPQLLDNSEVALH
CKDWLYLNLTGIRATDPSEASFTFGNFRHQRYDDLVIAALGLEHRHHLLPEIIDGSNITHALTKEAAALTGLRAGTPVSL
GYVDMVMTALGAGVHTGEANTACSIVGSTGVHLRSVSTDNVWLNSEQTGYVIQLPCPGYVTQVQTNMASTLNLDWLLHVA
SELLASFGCEVSHARLVQHLDRWLSEAKPGALLYHPYISEAGERGPFVNANARASLVGLSYSHGFADLVRAVIEGIGFAA
RDCYLAMGEQLPGELRLTGGAIRSPQLRQVLSACLGVPVRSSKREEAGAAGAAMMAAVAIGAYPSMEQCIATWVTPLLDA
PEPPSSALTDRYQHLFNCYQQLRRELPPAWNVLNPPSAAC

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790005, Length=504, Percent_Identity=26.1904761904762, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1789987, Length=509, Percent_Identity=28.0943025540275, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787789, Length=493, Percent_Identity=26.1663286004057, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789168, Length=482, Percent_Identity=23.4439834024896, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 56141; Mature: 56141

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00445 FGGY_KINASES_2 ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRDIILGLDSGTSVVKAVAFDLEGEQIECASVRNSYSRSAGGAAQQSMEQTWQDAVVS
CCCCCEEEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IRKLAERVENLAERVVAIAVTGQGDGTWLVGHQNRPVDDAWIWLDARAAPTVETLSRSPL
HHHHHHHHHHHHHHEEEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHCCCCH
ARARFEATGTGLNTCQQSAQMAHMDRFYPQLLDNSEVALHCKDWLYLNLTGIRATDPSEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEEEEEEECCCCCCC
SFTFGNFRHQRYDDLVIAALGLEHRHHLLPEIIDGSNITHALTKEAAALTGLRAGTPVSL
CEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCH
GYVDMVMTALGAGVHTGEANTACSIVGSTGVHLRSVSTDNVWLNSEQTGYVIQLPCPGYV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEECCCCCCEEEEECCCCHH
TQVQTNMASTLNLDWLLHVASELLASFGCEVSHARLVQHLDRWLSEAKPGALLYHPYISE
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHC
AGERGPFVNANARASLVGLSYSHGFADLVRAVIEGIGFAARDCYLAMGEQLPGELRLTGG
CCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCC
AIRSPQLRQVLSACLGVPVRSSKREEAGAAGAAMMAAVAIGAYPSMEQCIATWVTPLLDA
CCCCHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PEPPSSALTDRYQHLFNCYQQLRRELPPAWNVLNPPSAAC
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDNRDIILGLDSGTSVVKAVAFDLEGEQIECASVRNSYSRSAGGAAQQSMEQTWQDAVVS
CCCCCEEEEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IRKLAERVENLAERVVAIAVTGQGDGTWLVGHQNRPVDDAWIWLDARAAPTVETLSRSPL
HHHHHHHHHHHHHHEEEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCHHHHCCCCH
ARARFEATGTGLNTCQQSAQMAHMDRFYPQLLDNSEVALHCKDWLYLNLTGIRATDPSEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEEEEEEECCCCCCC
SFTFGNFRHQRYDDLVIAALGLEHRHHLLPEIIDGSNITHALTKEAAALTGLRAGTPVSL
CEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCH
GYVDMVMTALGAGVHTGEANTACSIVGSTGVHLRSVSTDNVWLNSEQTGYVIQLPCPGYV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEECCCCCCEEEEECCCCHH
TQVQTNMASTLNLDWLLHVASELLASFGCEVSHARLVQHLDRWLSEAKPGALLYHPYISE
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHC
AGERGPFVNANARASLVGLSYSHGFADLVRAVIEGIGFAARDCYLAMGEQLPGELRLTGG
CCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEECCC
AIRSPQLRQVLSACLGVPVRSSKREEAGAAGAAMMAAVAIGAYPSMEQCIATWVTPLLDA
CCCCHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PEPPSSALTDRYQHLFNCYQQLRRELPPAWNVLNPPSAAC
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1660563 [H]