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The map label for this gene is exuT [H]

Identifier: 218532114

GI number: 218532114

Start: 4434204

End: 4435511

Strand: Reverse

Name: exuT [H]

Synonym: Mchl_4209

Alternate gene names: 218532114

Gene position: 4435511-4434204 (Counterclockwise)

Preceding gene: 218532119

Following gene: 218532113

Centisome position: 76.77

GC content: 67.43

Gene sequence:

>1308_bases
ATGTCGAGGCTTGTCCGCTTCAAAGCCACGGATCGTGTGCTTCTGATCATCTGCCTGATGTATCTGGTCACGTATATCGA
CCGGGTGAACATCGGCACCGCGGCGCCGGCGATGCAGAAGGAGCTCGGGCTCAGCAATTTCGAGCTCGGCCTCGCGTTCT
CCGCCTTCGCCTATCCTTACGCGTTCTTTCAGATCGCCGGCGGCTGGTTGGGTGATCGACTCGGACCGCGGATGACGCTG
CTGATCTGCGGCACGATCTGGTCGGCCGCCACCGTGGCGATCGGCTTCGTCGAGGGGGCGGTCTCGCTCGTCATCGCCCG
CTTCGTCCTCGGCGTCGGCGAGGGCTCGGCCTTCCCGACCGCGACGCGGGCGCTGGCGAACTGGATGGCCGCCGACCGGC
GCGGCTTCGCGCAAGGGATCACCCACGCCTTCGCCCGGCTCGGCAACGCGTTGACGCCGCCGCTGATCGCAGTGCTGATC
GTCGCCCTGTCCTGGCGCGACTCGTTCGTCATCGTCGGCCTCATCAGCTTCGCCTGGGTCGCGCTCTGGTTCTGGTACTT
CCGGGACGATCCGCGCGACCACAAGCACGTGACGCCGGAGGAGATCGCCGTCCTGCCGACGGTGAAGATCGCGGGCGAGC
GCAAGGCCGTGCCGTGGCGGCGCCTGCTCAAGCGCATGCTGCCGGTGACGATTACCGACTTCTGCTACGGCTGGACGCTG
TGGCTGTTCCTCAACTGGATCCCGTCCTACTTCCTCCACCAGTACCAGCTCGACATCAAGAAGTCGGCGATCTTCGCCTC
GGGCGTGTTCTTCGCCGGCGTCGTCGGCGACACCGTCGGCGGGGTCGTCAGCGACCGCATCCTCAAGAAGACCGGCAGCG
TCTCGAAGGCGCGGGTGAGCGTGATCGTGGTCGGCTTCCTCGGCGCGTTCGTGTTCATGCTGCCGGTGCTGTTCGCGACC
GAACTCGTCACGATCACCCTATGCCTGTCGGGCGCCTTCTTCTTCGCCGAACTCATCGTCGCGCCGATCTGGGCGGTGCC
GATGGACATCGCGCCCCAGCATTCGGGCACCGCCTCCGGCTTTATGAACTTCGGCTTCGGGTTGGCCGGGATGATCTCGC
CCGTCGTGTTCGGCGCCGTCATCGACGCGACCGGCCGCTGGGACCTGCCCTTCGTCGCCTCGCTCGGCCTGCTGCTGCTC
GGCGCGGTGCTCGCCCTGCGGATGCGGCCGGACGAGCCCTTCCTCGACGACGTGGAGGAAACGCCGCCCGTCGCGACCGG
CCCGGCCGCGGTCCGGCCGCAGGTCTGA

Upstream 100 bases:

>100_bases
GACGAGAAACGCTCAACGCTTGCCACGTCGTGTCTTCGGTCATGCCTCGTACCATGCGCCGAGCCGAAGACATCCGCCCC
AAGGCGGCAGGAGGGCCGGA

Downstream 100 bases:

>100_bases
CCGCGGGACCCCGATTCTCCATCGAACTTCCCCCTTCGATCGCCGCAAGAGGACACTGCGATGGCCGTCGTCAATCTCAA
GGAGCCGGTCGCCGGGCCGG

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSRLVRFKATDRVLLIICLMYLVTYIDRVNIGTAAPAMQKELGLSNFELGLAFSAFAYPYAFFQIAGGWLGDRLGPRMTL
LICGTIWSAATVAIGFVEGAVSLVIARFVLGVGEGSAFPTATRALANWMAADRRGFAQGITHAFARLGNALTPPLIAVLI
VALSWRDSFVIVGLISFAWVALWFWYFRDDPRDHKHVTPEEIAVLPTVKIAGERKAVPWRRLLKRMLPVTITDFCYGWTL
WLFLNWIPSYFLHQYQLDIKKSAIFASGVFFAGVVGDTVGGVVSDRILKKTGSVSKARVSVIVVGFLGAFVFMLPVLFAT
ELVTITLCLSGAFFFAELIVAPIWAVPMDIAPQHSGTASGFMNFGFGLAGMISPVVFGAVIDATGRWDLPFVASLGLLLL
GAVLALRMRPDEPFLDDVEETPPVATGPAAVRPQV

Sequences:

>Translated_435_residues
MSRLVRFKATDRVLLIICLMYLVTYIDRVNIGTAAPAMQKELGLSNFELGLAFSAFAYPYAFFQIAGGWLGDRLGPRMTL
LICGTIWSAATVAIGFVEGAVSLVIARFVLGVGEGSAFPTATRALANWMAADRRGFAQGITHAFARLGNALTPPLIAVLI
VALSWRDSFVIVGLISFAWVALWFWYFRDDPRDHKHVTPEEIAVLPTVKIAGERKAVPWRRLLKRMLPVTITDFCYGWTL
WLFLNWIPSYFLHQYQLDIKKSAIFASGVFFAGVVGDTVGGVVSDRILKKTGSVSKARVSVIVVGFLGAFVFMLPVLFAT
ELVTITLCLSGAFFFAELIVAPIWAVPMDIAPQHSGTASGFMNFGFGLAGMISPVVFGAVIDATGRWDLPFVASLGLLLL
GAVLALRMRPDEPFLDDVEETPPVATGPAAVRPQV
>Mature_434_residues
SRLVRFKATDRVLLIICLMYLVTYIDRVNIGTAAPAMQKELGLSNFELGLAFSAFAYPYAFFQIAGGWLGDRLGPRMTLL
ICGTIWSAATVAIGFVEGAVSLVIARFVLGVGEGSAFPTATRALANWMAADRRGFAQGITHAFARLGNALTPPLIAVLIV
ALSWRDSFVIVGLISFAWVALWFWYFRDDPRDHKHVTPEEIAVLPTVKIAGERKAVPWRRLLKRMLPVTITDFCYGWTLW
LFLNWIPSYFLHQYQLDIKKSAIFASGVFFAGVVGDTVGGVVSDRILKKTGSVSKARVSVIVVGFLGAFVFMLPVLFATE
LVTITLCLSGAFFFAELIVAPIWAVPMDIAPQHSGTASGFMNFGFGLAGMISPVVFGAVIDATGRWDLPFVASLGLLLLG
AVLALRMRPDEPFLDDVEETPPVATGPAAVRPQV

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=370, Percent_Identity=25.1351351351351, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI154350196, Length=385, Percent_Identity=22.3376623376623, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI9966811, Length=394, Percent_Identity=23.8578680203046, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI21322234, Length=389, Percent_Identity=22.3650385604113, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI9945322, Length=362, Percent_Identity=22.3756906077348, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI148743791, Length=344, Percent_Identity=25.2906976744186, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4885441, Length=320, Percent_Identity=24.0625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082320, Length=386, Percent_Identity=30.5699481865285, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI2367379, Length=397, Percent_Identity=26.9521410579345, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789152, Length=410, Percent_Identity=28.780487804878, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789515, Length=402, Percent_Identity=30.3482587064677, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI2367193, Length=423, Percent_Identity=25.7683215130024, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788573, Length=428, Percent_Identity=22.4299065420561, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082071, Length=422, Percent_Identity=24.1706161137441, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788074, Length=361, Percent_Identity=24.3767313019391, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17552542, Length=376, Percent_Identity=25.531914893617, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=411, Percent_Identity=24.330900243309, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533556, Length=401, Percent_Identity=22.1945137157107, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI115533554, Length=401, Percent_Identity=22.1945137157107, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193205400, Length=428, Percent_Identity=22.6635514018692, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=386, Percent_Identity=22.020725388601, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=398, Percent_Identity=24.3718592964824, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71991453, Length=417, Percent_Identity=22.3021582733813, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71991448, Length=417, Percent_Identity=22.3021582733813, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=310, Percent_Identity=20.6451612903226, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=310, Percent_Identity=20.6451612903226, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=310, Percent_Identity=20.6451612903226, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=354, Percent_Identity=22.316384180791, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564204, Length=232, Percent_Identity=21.9827586206897, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17564202, Length=232, Percent_Identity=21.9827586206897, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=316, Percent_Identity=22.1518987341772, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573708, Length=458, Percent_Identity=24.6724890829694, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573707, Length=458, Percent_Identity=24.6724890829694, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24584153, Length=380, Percent_Identity=23.6842105263158, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24583789, Length=376, Percent_Identity=23.6702127659574, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19920686, Length=397, Percent_Identity=23.9294710327456, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24648416, Length=464, Percent_Identity=23.0603448275862, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356189, Length=464, Percent_Identity=23.0603448275862, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658674, Length=431, Percent_Identity=24.1299303944316, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28573299, Length=416, Percent_Identity=22.3557692307692, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45550460, Length=441, Percent_Identity=22.6757369614512, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24655255, Length=384, Percent_Identity=23.1770833333333, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639764, Length=422, Percent_Identity=23.696682464455, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24658658, Length=425, Percent_Identity=22.8235294117647, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550495, Length=456, Percent_Identity=23.2456140350877, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI62484226, Length=371, Percent_Identity=22.911051212938, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641682, Length=435, Percent_Identity=21.6091954022989, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24658666, Length=457, Percent_Identity=23.4135667396061, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24580790, Length=316, Percent_Identity=23.1012658227848, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24655271, Length=475, Percent_Identity=21.8947368421053, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20130135, Length=451, Percent_Identity=21.9512195121951, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20130167, Length=394, Percent_Identity=22.8426395939086, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24658689, Length=419, Percent_Identity=21.9570405727924, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654215, Length=420, Percent_Identity=20, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19922400, Length=420, Percent_Identity=20, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47388; Mature: 47257

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLVRFKATDRVLLIICLMYLVTYIDRVNIGTAAPAMQKELGLSNFELGLAFSAFAYPY
CCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
AFFQIAGGWLGDRLGPRMTLLICGTIWSAATVAIGFVEGAVSLVIARFVLGVGEGSAFPT
HHHHHHCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ATRALANWMAADRRGFAQGITHAFARLGNALTPPLIAVLIVALSWRDSFVIVGLISFAWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALWFWYFRDDPRDHKHVTPEEIAVLPTVKIAGERKAVPWRRLLKRMLPVTITDFCYGWTL
HHHHHHHCCCCCCCCCCCHHHHEEECCEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
WLFLNWIPSYFLHQYQLDIKKSAIFASGVFFAGVVGDTVGGVVSDRILKKTGSVSKARVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VIVVGFLGAFVFMLPVLFATELVTITLCLSGAFFFAELIVAPIWAVPMDIAPQHSGTASG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FMNFGFGLAGMISPVVFGAVIDATGRWDLPFVASLGLLLLGAVLALRMRPDEPFLDDVEE
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
TPPVATGPAAVRPQV
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLVRFKATDRVLLIICLMYLVTYIDRVNIGTAAPAMQKELGLSNFELGLAFSAFAYPY
CCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHH
AFFQIAGGWLGDRLGPRMTLLICGTIWSAATVAIGFVEGAVSLVIARFVLGVGEGSAFPT
HHHHHHCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ATRALANWMAADRRGFAQGITHAFARLGNALTPPLIAVLIVALSWRDSFVIVGLISFAWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALWFWYFRDDPRDHKHVTPEEIAVLPTVKIAGERKAVPWRRLLKRMLPVTITDFCYGWTL
HHHHHHHCCCCCCCCCCCHHHHEEECCEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
WLFLNWIPSYFLHQYQLDIKKSAIFASGVFFAGVVGDTVGGVVSDRILKKTGSVSKARVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VIVVGFLGAFVFMLPVLFATELVTITLCLSGAFFFAELIVAPIWAVPMDIAPQHSGTASG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FMNFGFGLAGMISPVVFGAVIDATGRWDLPFVASLGLLLLGAVLALRMRPDEPFLDDVEE
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
TPPVATGPAAVRPQV
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]