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The map label for this gene is sucD [H]

Identifier: 218532113

GI number: 218532113

Start: 4432701

End: 4434143

Strand: Reverse

Name: sucD [H]

Synonym: Mchl_4208

Alternate gene names: 218532113

Gene position: 4434143-4432701 (Counterclockwise)

Preceding gene: 218532114

Following gene: 218532112

Centisome position: 76.74

GC content: 67.64

Gene sequence:

>1443_bases
ATGGCCGTCGTCAATCTCAAGGAGCCGGTCGCCGGGCCGGAACCGGCCTCCGTCGAAACCGTCATGGACCGGGCCAGGGC
CGCACAGAAGGCGTTCGCCAACGTCGATCAGGAGACCGCCGACGCCGCCGTGCGGGCACTCGCATGGTCGCTCTACAAAC
CGGAGCACGCAAGCGAACTCGCCGAACTCGCGGTGCAGGACACAGGCCTCGGCAACGTCGCCGACAAGATCCGGAAAAAA
CAGCGCAAGACCTTCGGCACCCTGCGCGACCTGCTTCGCGCGCCGTCGGTCGGCGTGATCGAGCGCGACGAGGCGAAGGG
CCTCGTCAAGTACGCCAAGCCGATGGGGGTGATCGGCGCGGTGACGCCCTCGACCAATCCGGGCGCGACCCCGGTCAACA
AGGCGATGATGGCGGTCAAGGGCCGCAACGCCATCGTCGTCGCCCCGTCGCCTCTCGGCTACCGCACCACGTCCCGCATC
GTCGATCTGATGCGCGCGGAACTCAGCCAGATCGGGCTGCCCGAGGATCTCGTGCAGATCCTGCCGTCGCCGGTGACGAA
GGAGTCGACGGAAGCGCTGATGAAGGCCTGCGATCTCGTCGTGGTGACGGGCTCGCAGGACAATGTCCGCCGCGCCTATT
CGAGCGGGACGCCGGCCATCGGCGTCGGCGCCGGCAACGTGCCGGTGATCGTCGACGAGACCGCCGACCTCGACGCCGCC
GCCGAGCGCATCCGCGACTCGAAGATTTTCGACAACTCGACCTCCTGCTCCTCGGAGAACGCCGTCGTCATCGTCGATGC
GGTCTACGACGCGGCCCTGGCCGCGCTGGAACGGGCCGGCGCCTATCTCTGCACGCCGGAGGAGCGCGAGCGGGTGCTCG
GGCGGCTCTGGGTCAAGGGCAAGCTCAACCGCGACCTCATCGCCCGCGACGCTGGGGTGCTGGCGCAAGCCTTCGAGCTG
CCGGCGCAGGCGAGAGACAAGAGCTTCTTCCTCGTGGAGGAGGAAGGCGTCGGCAAAGGCTATCCGCTCTCGGGCGAGAA
GCTCGCCCTCGTGCTGACCGTCTACCGGGCGAGCGACTTCGCGGCGGCGAAAGATCGGGTGCGCGAGATCCTCGAGCACC
AGGGCAAGGGCCATTCCTGCGGCCTGCACACCACCGACATGGACCGCGCCCGCGAGTTGGCGGAAGAGCTCGACGTCGTG
CGGGTGCTGGTGAACTTCGCCCACACCTTCGGCAATGGCGGCGGCTTCAATTCCGGCCTCGGCTTCACCCTCAGCATGGG
CTGCGGCTCCTGGCAGAAAAACTCGATCTCCGAGAACCTGAGCTACCGGCACATGCTCAACATCACCCACCTCGTCACGC
CGATCCCCGAGGACAAGCCGAGCGAGGAAGAGCTGTTCGGGCCGCACTGGAAACGGATCGGCCACGAGGAGGCCGCGCGA
TGA

Upstream 100 bases:

>100_bases
CGTCGCGACCGGCCCGGCCGCGGTCCGGCCGCAGGTCTGACCGCGGGACCCCGATTCTCCATCGAACTTCCCCCTTCGAT
CGCCGCAAGAGGACACTGCG

Downstream 100 bases:

>100_bases
ACTTCCTGGAGCACGTCGCCAAGGCGCGGGTCCTCGCGCCCGCCGGCATCCCGGTCCCGCGCGCGGTGCTGTGCCGGACG
CCCGAGGAGGCCGCCGCCGC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MAVVNLKEPVAGPEPASVETVMDRARAAQKAFANVDQETADAAVRALAWSLYKPEHASELAELAVQDTGLGNVADKIRKK
QRKTFGTLRDLLRAPSVGVIERDEAKGLVKYAKPMGVIGAVTPSTNPGATPVNKAMMAVKGRNAIVVAPSPLGYRTTSRI
VDLMRAELSQIGLPEDLVQILPSPVTKESTEALMKACDLVVVTGSQDNVRRAYSSGTPAIGVGAGNVPVIVDETADLDAA
AERIRDSKIFDNSTSCSSENAVVIVDAVYDAALAALERAGAYLCTPEERERVLGRLWVKGKLNRDLIARDAGVLAQAFEL
PAQARDKSFFLVEEEGVGKGYPLSGEKLALVLTVYRASDFAAAKDRVREILEHQGKGHSCGLHTTDMDRARELAEELDVV
RVLVNFAHTFGNGGGFNSGLGFTLSMGCGSWQKNSISENLSYRHMLNITHLVTPIPEDKPSEEELFGPHWKRIGHEEAAR

Sequences:

>Translated_480_residues
MAVVNLKEPVAGPEPASVETVMDRARAAQKAFANVDQETADAAVRALAWSLYKPEHASELAELAVQDTGLGNVADKIRKK
QRKTFGTLRDLLRAPSVGVIERDEAKGLVKYAKPMGVIGAVTPSTNPGATPVNKAMMAVKGRNAIVVAPSPLGYRTTSRI
VDLMRAELSQIGLPEDLVQILPSPVTKESTEALMKACDLVVVTGSQDNVRRAYSSGTPAIGVGAGNVPVIVDETADLDAA
AERIRDSKIFDNSTSCSSENAVVIVDAVYDAALAALERAGAYLCTPEERERVLGRLWVKGKLNRDLIARDAGVLAQAFEL
PAQARDKSFFLVEEEGVGKGYPLSGEKLALVLTVYRASDFAAAKDRVREILEHQGKGHSCGLHTTDMDRARELAEELDVV
RVLVNFAHTFGNGGGFNSGLGFTLSMGCGSWQKNSISENLSYRHMLNITHLVTPIPEDKPSEEELFGPHWKRIGHEEAAR
>Mature_479_residues
AVVNLKEPVAGPEPASVETVMDRARAAQKAFANVDQETADAAVRALAWSLYKPEHASELAELAVQDTGLGNVADKIRKKQ
RKTFGTLRDLLRAPSVGVIERDEAKGLVKYAKPMGVIGAVTPSTNPGATPVNKAMMAVKGRNAIVVAPSPLGYRTTSRIV
DLMRAELSQIGLPEDLVQILPSPVTKESTEALMKACDLVVVTGSQDNVRRAYSSGTPAIGVGAGNVPVIVDETADLDAAA
ERIRDSKIFDNSTSCSSENAVVIVDAVYDAALAALERAGAYLCTPEERERVLGRLWVKGKLNRDLIARDAGVLAQAFELP
AQARDKSFFLVEEEGVGKGYPLSGEKLALVLTVYRASDFAAAKDRVREILEHQGKGHSCGLHTTDMDRARELAEELDVVR
VLVNFAHTFGNGGGFNSGLGFTLSMGCGSWQKNSISENLSYRHMLNITHLVTPIPEDKPSEEELFGPHWKRIGHEEAAR

Specific function: Catalyzes the reduction of succinate semialdehyde to succinyl-CoA. The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA. There is no activity with NAD(+) as cosubstrate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787493, Length=456, Percent_Identity=33.9912280701754, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1788797, Length=369, Percent_Identity=32.2493224932249, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.76 [H]

Molecular weight: Translated: 51690; Mature: 51559

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVNLKEPVAGPEPASVETVMDRARAAQKAFANVDQETADAAVRALAWSLYKPEHASEL
CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHH
AELAVQDTGLGNVADKIRKKQRKTFGTLRDLLRAPSVGVIERDEAKGLVKYAKPMGVIGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCCCEEEE
VTPSTNPGATPVNKAMMAVKGRNAIVVAPSPLGYRTTSRIVDLMRAELSQIGLPEDLVQI
ECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LPSPVTKESTEALMKACDLVVVTGSQDNVRRAYSSGTPAIGVGAGNVPVIVDETADLDAA
CCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHH
AERIRDSKIFDNSTSCSSENAVVIVDAVYDAALAALERAGAYLCTPEERERVLGRLWVKG
HHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCC
KLNRDLIARDAGVLAQAFELPAQARDKSFFLVEEEGVGKGYPLSGEKLALVLTVYRASDF
CCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCH
AAAKDRVREILEHQGKGHSCGLHTTDMDRARELAEELDVVRVLVNFAHTFGNGGGFNSGL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GFTLSMGCGSWQKNSISENLSYRHMLNITHLVTPIPEDKPSEEELFGPHWKRIGHEEAAR
CEEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCHHHCCC
>Mature Secondary Structure 
AVVNLKEPVAGPEPASVETVMDRARAAQKAFANVDQETADAAVRALAWSLYKPEHASEL
CEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHH
AELAVQDTGLGNVADKIRKKQRKTFGTLRDLLRAPSVGVIERDEAKGLVKYAKPMGVIGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCCCEEEE
VTPSTNPGATPVNKAMMAVKGRNAIVVAPSPLGYRTTSRIVDLMRAELSQIGLPEDLVQI
ECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LPSPVTKESTEALMKACDLVVVTGSQDNVRRAYSSGTPAIGVGAGNVPVIVDETADLDAA
CCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHH
AERIRDSKIFDNSTSCSSENAVVIVDAVYDAALAALERAGAYLCTPEERERVLGRLWVKG
HHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHCC
KLNRDLIARDAGVLAQAFELPAQARDKSFFLVEEEGVGKGYPLSGEKLALVLTVYRASDF
CCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEEEECCCCH
AAAKDRVREILEHQGKGHSCGLHTTDMDRARELAEELDVVRVLVNFAHTFGNGGGFNSGL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GFTLSMGCGSWQKNSISENLSYRHMLNITHLVTPIPEDKPSEEELFGPHWKRIGHEEAAR
CEEEECCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]