Click here to switch to the map view.

The map label for this gene is gsiC [H]

Identifier: 218531962

GI number: 218531962

Start: 4266874

End: 4267854

Strand: Reverse

Name: gsiC [H]

Synonym: Mchl_4050

Alternate gene names: 218531962

Gene position: 4267854-4266874 (Counterclockwise)

Preceding gene: 218531963

Following gene: 218531961

Centisome position: 73.87

GC content: 67.48

Gene sequence:

>981_bases
ATGTTCGTTCTCAGTTTCCTCGCCCGGCGCCTCGCGCAGGGTGCGGTCATCATCTTCCTCGTCTCGCTGCTGATCTTCAC
CCTGCTGCGGGTGATGTCGGGCAACCCCGTGCGCCAGATGGTGGGCGGGATGGCGCCCGACTCCCTGGTGGAGCAGATCG
CCACCACCATGGGCCTGCGCGATCCGATCATCGTGCAGTTCGGCCGCTACGCGGCAGGGGTGGTCCAGGGTGATCTCGGC
CGCAGCTTCATGCGGCCGGCCAACGGCGCGGCGACGGGGGGCGCGAATTTCGACGATATGACCCGCGGCGAGCGGGCCGG
GGTCGGCGATCTCATCCTCGACGCCCTGCCGATGACCCTGCAACTCGCCGCCCTGGCGCTCGCCATCGCCCTGGTCTTCT
CGGCCCTGCTCGGGATCGCGGCCGGCCTGCGCCCCGGCGGGTTCTTCGACCGGCTCGCCTTCGCGGTCTCCTCGGTCTTC
ATCTCGATCCCGAATTTCTGGCTCGGCATCGTGCTCGCCTTGCTCCTGTCGGTGAAGCTCGGCTGGCTGCCGGCGATCGG
CTATGGCGGCTTCTCCTATACGGTGCTGCCGGCCCTGGTGCTCGCCGTCGAACTGTCGCCGGTGCTGATCCGGACGCTGT
CGAGCGCGGTGGCGGCGCAGATGGGCGAGTCTTACGTCGCCGTCGGCCATGTCCGCGGCCTGTCGCGCCCGCGCATCGTC
GCCGCGCATGCCCTGCGCAACGCCTCGGTGCCGCTCCTCAACCTGCTCGGTGTGCAGTTCTCCTCGCTGCTCGGGGGCGT
GATCATCGTCGAATACATCTTCGACTATCCCGGCCTCGGACTGCTCACCATCAACGCTGTGCTCCAGCGCGACTTTCCGC
TGATCCAGGGCATCGCGATCGTCACCAGCGCGATCTTCGTCCTCATCAACATCCTCGTCGATCTCGCGGCGACCACCATC
GATCCGAGGCTCGAATACTGA

Upstream 100 bases:

>100_bases
CCGCCTGACTGAACTGTCCGCGCCCGGCGCGTGACCCGGCCCGCCTCCGCGGGCGGCCGGGCCCCGCCCCGCCGATTCCG
TCACCGGACCCGATGCCCCG

Downstream 100 bases:

>100_bases
TGGATGCCGTGGATTCTTCCCTGGCGCTGGTTCCGCCCCGCGTCGATGTCACGGCCTCGCGCTCCATCGGCCGGCGCATC
CTCGGGCGCGCCGCCCGTTC

Product: binding-protein-dependent transporters inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFVLSFLARRLAQGAVIIFLVSLLIFTLLRVMSGNPVRQMVGGMAPDSLVEQIATTMGLRDPIIVQFGRYAAGVVQGDLG
RSFMRPANGAATGGANFDDMTRGERAGVGDLILDALPMTLQLAALALAIALVFSALLGIAAGLRPGGFFDRLAFAVSSVF
ISIPNFWLGIVLALLLSVKLGWLPAIGYGGFSYTVLPALVLAVELSPVLIRTLSSAVAAQMGESYVAVGHVRGLSRPRIV
AAHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLAATTI
DPRLEY

Sequences:

>Translated_326_residues
MFVLSFLARRLAQGAVIIFLVSLLIFTLLRVMSGNPVRQMVGGMAPDSLVEQIATTMGLRDPIIVQFGRYAAGVVQGDLG
RSFMRPANGAATGGANFDDMTRGERAGVGDLILDALPMTLQLAALALAIALVFSALLGIAAGLRPGGFFDRLAFAVSSVF
ISIPNFWLGIVLALLLSVKLGWLPAIGYGGFSYTVLPALVLAVELSPVLIRTLSSAVAAQMGESYVAVGHVRGLSRPRIV
AAHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLAATTI
DPRLEY
>Mature_326_residues
MFVLSFLARRLAQGAVIIFLVSLLIFTLLRVMSGNPVRQMVGGMAPDSLVEQIATTMGLRDPIIVQFGRYAAGVVQGDLG
RSFMRPANGAATGGANFDDMTRGERAGVGDLILDALPMTLQLAALALAIALVFSALLGIAAGLRPGGFFDRLAFAVSSVF
ISIPNFWLGIVLALLLSVKLGWLPAIGYGGFSYTVLPALVLAVELSPVLIRTLSSAVAAQMGESYVAVGHVRGLSRPRIV
AAHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLAATTI
DPRLEY

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=32.4074074074074, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=31.9018404907975, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789965, Length=357, Percent_Identity=29.1316526610644, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787497, Length=329, Percent_Identity=25.531914893617, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787761, Length=353, Percent_Identity=29.7450424929178, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787550, Length=246, Percent_Identity=29.2682926829268, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788504, Length=303, Percent_Identity=23.7623762376238, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34432; Mature: 34432

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLSFLARRLAQGAVIIFLVSLLIFTLLRVMSGNPVRQMVGGMAPDSLVEQIATTMGLR
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCC
DPIIVQFGRYAAGVVQGDLGRSFMRPANGAATGGANFDDMTRGERAGVGDLILDALPMTL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
QLAALALAIALVFSALLGIAAGLRPGGFFDRLAFAVSSVFISIPNFWLGIVLALLLSVKL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GWLPAIGYGGFSYTVLPALVLAVELSPVLIRTLSSAVAAQMGESYVAVGHVRGLSRPRIV
HCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
AAHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVLINILVDLAATTIDPRLEY
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFVLSFLARRLAQGAVIIFLVSLLIFTLLRVMSGNPVRQMVGGMAPDSLVEQIATTMGLR
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHCCC
DPIIVQFGRYAAGVVQGDLGRSFMRPANGAATGGANFDDMTRGERAGVGDLILDALPMTL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
QLAALALAIALVFSALLGIAAGLRPGGFFDRLAFAVSSVFISIPNFWLGIVLALLLSVKL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GWLPAIGYGGFSYTVLPALVLAVELSPVLIRTLSSAVAAQMGESYVAVGHVRGLSRPRIV
HCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHH
AAHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVLINILVDLAATTIDPRLEY
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]