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The map label for this gene is pabA [H]

Identifier: 218236126

GI number: 218236126

Start: 75966

End: 76553

Strand: Direct

Name: pabA [H]

Synonym: BCB4264_A0077

Alternate gene names: 218236126

Gene position: 75966-76553 (Clockwise)

Preceding gene: 218234958

Following gene: 218236092

Centisome position: 1.4

GC content: 39.29

Gene sequence:

>588_bases
ATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACAAGAGCTCGT
TGTTAAACGTAACGATGAAGTGACCATTTCAGATATTGAGAATATGAAACCAGATTTTCTAATGATTTCTCCAGGCCCAT
GTAGTCCTAATGAAGCTGGGATTAGTATGGAAGCTATTAAATACTTTGCTGGAAAGACTCCGATTTTTGGTGTTTGTCTA
GGGCATCAATCCATTGCACAAGTGTTTGGGGGAGAGGTTGTCCGTGCAGAGCGATTAATGCATGGAAAAACGTCGCTTAT
GCATCATGATGGAAAGACGATTTTTTCGGATATTCCTAATCCGTTTACTGCGACGCGCTATCATTCCCTTATTGTTAAGA
AAGAGACGTTACCCGATTGCTTAGAGGTAACGTCTTGGACAGAGGAAGGGGAAATTATGGCACTTCGTCATAAGACATTG
CCGATAGAGGGTGTGCAATTCCATCCAGAATCTATTATGACTTCTCATGGGAAAGAGCTGTTGCAGAATTTCATTCGTAA
ATACAGTCCAAGTGCGACATTATGTTAA

Upstream 100 bases:

>100_bases
TTGATTCAAATCCGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTATGGCGTGCAAAAGAACGTAGCGAA
GAAACGGTTAGGTGAGAGAA

Downstream 100 bases:

>100_bases
TTTACGTAAATGGTCAGTATGTAGAAGCAAGTGAAGCGAGAATTTCTCCTTATGATCATGGTTATTTATATGGTCTTGGA
GTTTTTGAAACGTTTCGTAT

Product: para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEAIKYFAGKTPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHKTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSATLC

Sequences:

>Translated_195_residues
MILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEAIKYFAGKTPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHKTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSATLC
>Mature_195_residues
MILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMEAIKYFAGKTPIFGVCL
GHQSIAQVFGGEVVRAERLMHGKTSLMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHKTL
PIEGVQFHPESIMTSHGKELLQNFIRKYSPSATLC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=56.6844919786096, Blast_Score=252, Evalue=1e-68,
Organism=Escherichia coli, GI1787517, Length=200, Percent_Identity=40.5, Blast_Score=153, Evalue=7e-39,
Organism=Escherichia coli, GI1786215, Length=177, Percent_Identity=27.683615819209, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788854, Length=191, Percent_Identity=26.7015706806283, Blast_Score=61, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=48.6486486486487, Blast_Score=199, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=30.8056872037915, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281365319, Length=139, Percent_Identity=29.4964028776978, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21862; Mature: 21862

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEECCCCCCCCCCC
ISMEAIKYFAGKTPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSLMHHDGKTIFSDIPN
CHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCHHHHCCCC
PFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHKTLPIEGVQFHPESIMTSHGKEL
CCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LQNFIRKYSPSATLC
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEECCCCCCCCCCC
ISMEAIKYFAGKTPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSLMHHDGKTIFSDIPN
CHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCHHHHCCCC
PFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHKTLPIEGVQFHPESIMTSHGKEL
CCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LQNFIRKYSPSATLC
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]