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The map label for this gene is pabC [H]

Identifier: 218236092

GI number: 218236092

Start: 76547

End: 77419

Strand: Direct

Name: pabC [H]

Synonym: BCB4264_A0078

Alternate gene names: 218236092

Gene position: 76547-77419 (Clockwise)

Preceding gene: 218236126

Following gene: 218233849

Centisome position: 1.41

GC content: 34.94

Gene sequence:

>873_bases
ATGTTAATTTACGTAAATGGTCAGTATGTAGAAGCAAGTGAAGCGAGAATTTCTCCTTATGATCATGGTTATTTATATGG
TCTTGGAGTTTTTGAAACGTTTCGTATTTATAATGGTCATCCTTTCTTATTGGATGATCATTATAACCGTTTAATAGAGG
CGCTGGATACATTGCAAATTAAATGGACAATGACAAAAAATGATGTGATGCTTATTTTGAAAGATTTACTCGCTAAGAAT
GAATTGAAGCATGCATATGTACGTTTTAATGTATCGGCGGGTATAGATGAAATAGGATTACAAACGGAAATGTATGAAGA
GCCTTCTGTTATTGTTTTTATAAAACCTTTAACAGCTCCAGGGGATGTAGTGGAAAAAGAAGGTGTTATTCTAAAACAAG
TGCGAAATACACCGGAAGGGACATTTCGCCTGAAGTCTCATCACTATTTAAATAATATTTTAGGGAAGCGTGAAATTGGA
AATGTTGTGAGTAAGGAAGGTATTTTCCTCACTGAAGCAGGTTATGTTGCAGAGGGTATTGTTTCGAATCTATTTTTTGT
GAAAGGTGATGTTTTATATACACCTTCGTTAGAGACAGGGATTTTAAATGGTATCACTCGTGCGTTTATTATAAAGAGTG
CTGAAGAATTAAATATAGAAGTAAAGGAAGGTTTCTTTACAAAAGATGAGCTACTTTCAGCGGATGAAGTCTTCGTAACA
AACTCCATTCAAGAAATTGTTCCGCTTTATCGTATAGAAGCGCAGGATTTCCCGGGTAAAGTAGGAGTGGTTACAAAAAG
TTTAATGTACCTTTATGGAATGCAAAGAGAGAAATTATGGAGCAGAAATGAATTACGAAGAGGAGATGTGTAG

Upstream 100 bases:

>100_bases
CGATAGAGGGTGTGCAATTCCATCCAGAATCTATTATGACTTCTCATGGGAAAGAGCTGTTGCAGAATTTCATTCGTAAA
TACAGTCCAAGTGCGACATT

Downstream 100 bases:

>100_bases
TTTGAAGTGGGATTATGATTTGCGCTGCGGCGAATATACATTGAATTTAAATGAAAAAACATTAATTATGGGGATTTTAA
ATGTAACACCAGATTCGTTT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLIYVNGQYVEASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYNRLIEALDTLQIKWTMTKNDVMLILKDLLAKN
ELKHAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLTAPGDVVEKEGVILKQVRNTPEGTFRLKSHHYLNNILGKREIG
NVVSKEGIFLTEAGYVAEGIVSNLFFVKGDVLYTPSLETGILNGITRAFIIKSAEELNIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLYRIEAQDFPGKVGVVTKSLMYLYGMQREKLWSRNELRRGDV

Sequences:

>Translated_290_residues
MLIYVNGQYVEASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYNRLIEALDTLQIKWTMTKNDVMLILKDLLAKN
ELKHAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLTAPGDVVEKEGVILKQVRNTPEGTFRLKSHHYLNNILGKREIG
NVVSKEGIFLTEAGYVAEGIVSNLFFVKGDVLYTPSLETGILNGITRAFIIKSAEELNIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLYRIEAQDFPGKVGVVTKSLMYLYGMQREKLWSRNELRRGDV
>Mature_290_residues
MLIYVNGQYVEASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYNRLIEALDTLQIKWTMTKNDVMLILKDLLAKN
ELKHAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLTAPGDVVEKEGVILKQVRNTPEGTFRLKSHHYLNNILGKREIG
NVVSKEGIFLTEAGYVAEGIVSNLFFVKGDVLYTPSLETGILNGITRAFIIKSAEELNIEVKEGFFTKDELLSADEVFVT
NSIQEIVPLYRIEAQDFPGKVGVVTKSLMYLYGMQREKLWSRNELRRGDV

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=281, Percent_Identity=30.9608540925267, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787338, Length=255, Percent_Identity=25.8823529411765, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 32997; Mature: 32997

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYVNGQYVEASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYNRLIEALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEECHHEEEEEECCCEEEECHHHHHHHHHHHCEEE
KWTMTKNDVMLILKDLLAKNELKHAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLTAP
EEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GDVVEKEGVILKQVRNTPEGTFRLKSHHYLNNILGKREIGNVVSKEGIFLTEAGYVAEGI
CCHHHCCCHHHHHHCCCCCCEEEECCHHHHHHHHCHHHHHHHHHCCCEEEEECCHHHHHH
VSNLFFVKGDVLYTPSLETGILNGITRAFIIKSAEELNIEVKEGFFTKDELLSADEVFVT
HHHEEEEECCEEECCCHHHHHHHHHHHHHHEECHHHCEEEEECCCCCHHHHCCCCCEEEC
NSIQEIVPLYRIEAQDFPGKVGVVTKSLMYLYGMQREKLWSRNELRRGDV
CCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLIYVNGQYVEASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYNRLIEALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEECHHEEEEEECCCEEEECHHHHHHHHHHHCEEE
KWTMTKNDVMLILKDLLAKNELKHAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLTAP
EEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GDVVEKEGVILKQVRNTPEGTFRLKSHHYLNNILGKREIGNVVSKEGIFLTEAGYVAEGI
CCHHHCCCHHHHHHCCCCCCEEEECCHHHHHHHHCHHHHHHHHHCCCEEEEECCHHHHHH
VSNLFFVKGDVLYTPSLETGILNGITRAFIIKSAEELNIEVKEGFFTKDELLSADEVFVT
HHHEEEEECCEEECCCHHHHHHHHHHHHHHEECHHHCEEEEECCCCCHHHHCCCCCEEEC
NSIQEIVPLYRIEAQDFPGKVGVVTKSLMYLYGMQREKLWSRNELRRGDV
CCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]