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The map label for this gene is pabB [H]

Identifier: 218234958

GI number: 218234958

Start: 74563

End: 75960

Strand: Direct

Name: pabB [H]

Synonym: BCB4264_A0076

Alternate gene names: 218234958

Gene position: 74563-75960 (Clockwise)

Preceding gene: 218231495

Following gene: 218236126

Centisome position: 1.38

GC content: 38.34

Gene sequence:

>1398_bases
ATGCAACGAAGAAAATCTTTAGCGCTTTCTATTCCATATCAGTTAGATTTCTTTAAGCAATATAAATTTCTTTCTCAGGG
TAAATCGCAACATATTTTGTTAGAAAGCGGCCGTGGCGGTCGTTATAACATTGTAGGGCTGAACCCAGTAGCGGTAATTC
GAGGGAAGGATGAAACGTTACATATAAGTGAAAGTGGTAAGGAAACAATAAAACGAGGGAATCCGTTAGATTTAATGCAA
GAATATATGGAACAATGGAAGACGGACTATAACCCAGAGTATCCGCCTTTTCAAGGTGGTGCAATTGGCTATTTCAGTTA
TGACTGTATCCGTTATATTGAAAAGCTGCCTTCTCTTGCGGAAGATGATATTAATATACCTGACATCTTCTTTTTATTAT
TTGATGACGTATTTGTCTATGATCAAAAAGAACAAGTGTTATGGGTTATTACGCATTATGTAGATAAATATGAAGAGGCG
AAAGAACGGCTAAATGAGTGGAAGAGTCTTTGGATGACAGAAGCGCCTGAAGTGACCGTGCCCTTTGAAAGTCCTGAAAA
GAAAAGTGAAGCAGTTGCTTTTACTGAAGCCAGCTTTATGAAGGCAGTTGAATGTATTCAAGAATATATTGGGGCGGGTG
ATGTGTTCCAAGTAAACTTGTCGACGAGACAAGAAAGAACGTTACAGACACACCCACTAGAAATTTATACAAGTCTTCGT
GAGATTAATCCATCTCCGTATATGGGTTACCTGGAGCTTGGGGATTTTCAAATTGTTAGTGGATCGCCAGAGTTGTTAAT
TAAGAAACAAGGAACTGAAGTAAGTACAAGACCGATTGCTGGAACGAGATCTAGAGGCGCGGATGAGCAAGAGGATGAAG
AATTAGCAAGAGAATTAATTGAGAACGAAAAAGAAAGAGCAGAGCATGTAATGCTTGTGGATTTAGAAAGAAATGATTTA
GGACGTGTTTGTAAATATGGCACTGTAGAAGTAGATGAATTTATGGTAATTGAGAAATACTCACATGTTATGCATATTGT
TTCTAATGTGCGTGGTGAGGTGGAAGAAGATAAAGATGCTTTTGATTTAGTGAAGGCTGTATTCCCTGGGGGAACAATTA
CTGGTGCCCCAAAAATACGTACGATGGAAATTATTGAGGAATTAGAACCTGTTCGAAGAGGGATTTATACAGGTTCAATC
GGTTGGATTGGTTATTCTGGAGATACAGAATTGAATATTGTAATTAGAACACTTCTTGCTAAAGATGGAAAAGCTCATGT
ACAAGCAGGGGCGGGAATTGTAATTGATTCAAATCCGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTAT
GGCGTGCAAAAGAACGTAGCGAAGAAACGGTTAGGTGA

Upstream 100 bases:

>100_bases
TTCACTAGCCTTCGAGTATAATCAATCTCTATATAAATAACTTATGTAGTTTGAGCTGGTTTATCTAAGAGGGTGGGATA
AAAGAAGACGGGGTGTTGAT

Downstream 100 bases:

>100_bases
GAGAAATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACAAGAG
CTCGTTGTTAAACGTAACGA

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQRRKSLALSIPYQLDFFKQYKFLSQGKSQHILLESGRGGRYNIVGLNPVAVIRGKDETLHISESGKETIKRGNPLDLMQ
EYMEQWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEQVLWVITHYVDKYEEA
KERLNEWKSLWMTEAPEVTVPFESPEKKSEAVAFTEASFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGADEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Sequences:

>Translated_465_residues
MQRRKSLALSIPYQLDFFKQYKFLSQGKSQHILLESGRGGRYNIVGLNPVAVIRGKDETLHISESGKETIKRGNPLDLMQ
EYMEQWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEQVLWVITHYVDKYEEA
KERLNEWKSLWMTEAPEVTVPFESPEKKSEAVAFTEASFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGADEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
>Mature_465_residues
MQRRKSLALSIPYQLDFFKQYKFLSQGKSQHILLESGRGGRYNIVGLNPVAVIRGKDETLHISESGKETIKRGNPLDLMQ
EYMEQWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEQVLWVITHYVDKYEEA
KERLNEWKSLWMTEAPEVTVPFESPEKKSEAVAFTEASFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGADEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=425, Percent_Identity=36.9411764705882, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1787518, Length=366, Percent_Identity=38.5245901639344, Blast_Score=238, Evalue=6e-64,
Organism=Escherichia coli, GI1786809, Length=205, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082077, Length=216, Percent_Identity=24.537037037037, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=473, Percent_Identity=36.9978858350951, Blast_Score=300, Evalue=4e-82,
Organism=Saccharomyces cerevisiae, GI6324361, Length=411, Percent_Identity=25.5474452554745, Blast_Score=117, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 53168; Mature: 53168

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRRKSLALSIPYQLDFFKQYKFLSQGKSQHILLESGRGGRYNIVGLNPVAVIRGKDETL
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISESGKETIKRGNPLDLMQEYMEQWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLA
EECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCC
EDDINIPDIFFLLFDDVFVYDQKEQVLWVITHYVDKYEEAKERLNEWKSLWMTEAPEVTV
CCCCCCCHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
PFESPEKKSEAVAFTEASFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGADEQEDEELARELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHH
KDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRRKSLALSIPYQLDFFKQYKFLSQGKSQHILLESGRGGRYNIVGLNPVAVIRGKDETL
CCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISESGKETIKRGNPLDLMQEYMEQWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLA
EECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCC
EDDINIPDIFFLLFDDVFVYDQKEQVLWVITHYVDKYEEAKERLNEWKSLWMTEAPEVTV
CCCCCCCHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
PFESPEKKSEAVAFTEASFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGADEQEDEELARELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHH
KDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]