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The map label for this gene is kinB3 [H]

Identifier: 218235962

GI number: 218235962

Start: 4023747

End: 4025021

Strand: Reverse

Name: kinB3 [H]

Synonym: BCB4264_A4112

Alternate gene names: 218235962

Gene position: 4025021-4023747 (Counterclockwise)

Preceding gene: 218231924

Following gene: 218235191

Centisome position: 74.28

GC content: 32.94

Gene sequence:

>1275_bases
ATGGAGCTTATCCGTGATTTATTGATTCAAATTGCCATCATAATTTTGCCACTATTTTTATATGAAGCGATTCGTTTAAA
TCGCTATCAAGAAATGCCTCCGAAGCCAAATCGTTACTTTATTATGTTTTTATCTAGCGTTACGCTCGTTCTCTCCATGA
CATACTCTATTTGTTTTGGCAATGTGTGTGGGTATAACTTTCATCCCATTCCAATTGTCAGTGGTTTTTTATATGGTGGG
ATTGTTGGTTTAATCCCAGCGGTTATTTTTGTTGCATACGAATGGTTACTAAAGGGAATGAGCTTTCTTCCAGTTTTAGA
AGTAATATTTTTATTGATAGTTCCGCTATTTTTATCAAAGAAATGGTCTCTTTTTTCAAGGGATAAGAAATTAATTTTAG
CATTTATGATTTCATCATTTTATGTGCTTGTTTCTTTAGTATTAGGCATGATTAATGTTCTTTTGGAAACAGGATTTACA
CCGTATATTTCGCAAATATATAGCGGATTTATATTTGCCTCGCTTATCATGGTCATGACAATGGTATTCCAGGTGTATTT
AACTGAATATTTAAATGAAAATGCATTGCTACGTACAGAGATGCAAAAATCAGAAAAGCTTAATATTGTAAGTGAGTTAG
CAGCAAGTGTGGCACATGAAGTTCGAAATCCACTAACTGTTGTTCGTGGATTTATCCAATTGCTAGAAAGTACGGAAGAT
GTGAAGAATAAGGATTATATGCGTCTCGTATTAGCTGAATTGGATCGGGCGGAACAAATTATTTCAGATTACTTAAATTT
AGCAAGGCCACAAATTGAGAAAAAAGAACACATTTGTTTATCAGCCCAATTAATAGAAATGACCACTCTTATGTCGTCAT
TTGCAGCGATGCAAGGTGTATATTTACAAGTTGAAATTTCAGAAAGTCTTTATACGATTGGTGATAAGACAAAATTGAAG
CAAGCCATTATGAATGTTGTTAAAAATGGTATTGAAGCAATTCAAGGAAATAAAGGATATTTAAAAGTAACAGCTATTCA
AAAAGATGAAACAATCATAATAAGAGTTAAAGATAGTGGTGTTGGTATGACGAAAGAACAGTTAGCAAGGCTTGGGCAAC
CATATTATTCTTTAAAAGAAAAAGGGACAGGATTAGGACTTATGGTAACATTTAGTATTTTACAAGCGCATAATGGTACA
TTGGAATATAAGAGTGAAAGTGGAAAAGGCACTGAAGCAATTATTATATTACCAGCTGTACAAAATAAGGAATAA

Upstream 100 bases:

>100_bases
AAAGAATTAACAAATATGTTAAGAAAAATCAAAATTTTAAAACAAATACACCTATAAAATGATATAATCATATCAAAATA
CATATAGGGGATGAGAGGTT

Downstream 100 bases:

>100_bases
AAGTTACCGATGAAAGGTAACTTTTTATTTTATATTGTTTATTCATTTGTTTTTTCTTGTTTTGCTCGGCTAAATAAACT
TTTAAATGATTGAAAGAAGC

Product: sporulation kinase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MELIRDLLIQIAIIILPLFLYEAIRLNRYQEMPPKPNRYFIMFLSSVTLVLSMTYSICFGNVCGYNFHPIPIVSGFLYGG
IVGLIPAVIFVAYEWLLKGMSFLPVLEVIFLLIVPLFLSKKWSLFSRDKKLILAFMISSFYVLVSLVLGMINVLLETGFT
PYISQIYSGFIFASLIMVMTMVFQVYLTEYLNENALLRTEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLESTED
VKNKDYMRLVLAELDRAEQIISDYLNLARPQIEKKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISESLYTIGDKTKLK
QAIMNVVKNGIEAIQGNKGYLKVTAIQKDETIIIRVKDSGVGMTKEQLARLGQPYYSLKEKGTGLGLMVTFSILQAHNGT
LEYKSESGKGTEAIIILPAVQNKE

Sequences:

>Translated_424_residues
MELIRDLLIQIAIIILPLFLYEAIRLNRYQEMPPKPNRYFIMFLSSVTLVLSMTYSICFGNVCGYNFHPIPIVSGFLYGG
IVGLIPAVIFVAYEWLLKGMSFLPVLEVIFLLIVPLFLSKKWSLFSRDKKLILAFMISSFYVLVSLVLGMINVLLETGFT
PYISQIYSGFIFASLIMVMTMVFQVYLTEYLNENALLRTEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLESTED
VKNKDYMRLVLAELDRAEQIISDYLNLARPQIEKKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISESLYTIGDKTKLK
QAIMNVVKNGIEAIQGNKGYLKVTAIQKDETIIIRVKDSGVGMTKEQLARLGQPYYSLKEKGTGLGLMVTFSILQAHNGT
LEYKSESGKGTEAIIILPAVQNKE
>Mature_424_residues
MELIRDLLIQIAIIILPLFLYEAIRLNRYQEMPPKPNRYFIMFLSSVTLVLSMTYSICFGNVCGYNFHPIPIVSGFLYGG
IVGLIPAVIFVAYEWLLKGMSFLPVLEVIFLLIVPLFLSKKWSLFSRDKKLILAFMISSFYVLVSLVLGMINVLLETGFT
PYISQIYSGFIFASLIMVMTMVFQVYLTEYLNENALLRTEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLESTED
VKNKDYMRLVLAELDRAEQIISDYLNLARPQIEKKEHICLSAQLIEMTTLMSSFAAMQGVYLQVEISESLYTIGDKTKLK
QAIMNVVKNGIEAIQGNKGYLKVTAIQKDETIIIRVKDSGVGMTKEQLARLGQPYYSLKEKGTGLGLMVTFSILQAHNGT
LEYKSESGKGTEAIIILPAVQNKE

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=31.6602316602317, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=33.6322869955157, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=28.695652173913, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=23.394495412844, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI145693157, Length=291, Percent_Identity=25.4295532646048, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=27.1966527196653, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=27.0491803278689, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=221, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=23.8317757009346, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=23.8532110091743, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=26.4840182648402, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47849; Mature: 47849

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIRDLLIQIAIIILPLFLYEAIRLNRYQEMPPKPNRYFIMFLSSVTLVLSMTYSICFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHC
NVCGYNFHPIPIVSGFLYGGIVGLIPAVIFVAYEWLLKGMSFLPVLEVIFLLIVPLFLSK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
KWSLFSRDKKLILAFMISSFYVLVSLVLGMINVLLETGFTPYISQIYSGFIFASLIMVMT
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MVFQVYLTEYLNENALLRTEMQKSEKLNIVSELAASVAHEVRNPLTVVRGFIQLLESTED
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
VKNKDYMRLVLAELDRAEQIISDYLNLARPQIEKKEHICLSAQLIEMTTLMSSFAAMQGV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
YLQVEISESLYTIGDKTKLKQAIMNVVKNGIEAIQGNKGYLKVTAIQKDETIIIRVKDSG
EEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEEECCC
VGMTKEQLARLGQPYYSLKEKGTGLGLMVTFSILQAHNGTLEYKSESGKGTEAIIILPAV
CCCCHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECC
QNKE
CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]