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The map label for this gene is malR [H]

Identifier: 218231924

GI number: 218231924

Start: 4026832

End: 4027854

Strand: Reverse

Name: malR [H]

Synonym: BCB4264_A4116

Alternate gene names: 218231924

Gene position: 4027854-4026832 (Counterclockwise)

Preceding gene: 218230867

Following gene: 218235962

Centisome position: 74.33

GC content: 36.56

Gene sequence:

>1023_bases
ATGACAGTTACAATTAAAGATGTGGCGAAGCAAGCGAATGTGGCACCATCAACAGTTTCTCGTGTAATTGCTGATAATCC
AAGTATAAGTGAAAAGACAAAGCGCCGTGTTAGGAAAGTGATGAGTGAATTAGGGTATCATCCCAATTTAAATGCGAGAA
ATCTTGCGAACCAAACGACGAAAACACTTGGTCTTGTTATGCCAAGTTCTGCAAGTAAAGCTTTTCAAAATCCATTTTTC
CCAGAAGTTATAAGAGGGATTAGTTCATTTGCACACGTAGAAGGTTATGCGCTTTACATGTCGACAGGTGAAACGGAAGA
GGAAATTTTTAATGGTGTCGTAAAGATGGTACAGGGACGCCAAATTGGTGGCATTATTCTTTTATATTCAAGGGAGAATG
ATCGGATTATTCAATATTTACATGAACAAAATTTCCCGTTTGTTTTAATAGGAAAACCATATGATCGAAAAGATGAAATT
ACATATGTAGATAATGACAATTATACAGCTGCAAGAGAAGTGGCAGAATATTTAATTTCATTAGGGCATAAGCAAATCGC
GTTCATTGGTGGTGGATCAGATTTACTTGTAACGAGAGATCGTTTAGCTGGTATGAGTGATGCCTTGAAATTAGCAGACA
TTGTATTACCAAAAGAATATATTTTACATTTTGATTTTTCGAGGGAAAGTGGTCAACAAGCTGTTGAGGAATTAATGGGA
CTGCAGCAACCGCCAACGGCAATTATGGCAACCGATGACTTAATTGGACTTGGTGTGTTAAGTGCTCTTTCTAAAAAAGG
ATTCGTTGTACCGAAAGATGTTTCTATTGTAAGCTTTAATAATGCTTTATTATCAGAAATTGCGAGCCCTCCACTTTCGA
CAGTTGATGTGAATATTTATCAGCTAGGATATGAGGCAGCAAAAGCTTTAGTTGATAAAGTAGAGAATGCAGAATCCACT
GCAAAGTGTATCATTATTCCTCATAAATTACTAAAACGTCAAACTTGTGATCATTATGCATAA

Upstream 100 bases:

>100_bases
TTAGTTTTGCAAGATATAAGAAATGAAAGTTTATGACTTGCAATGAGTGCGAGATAAAATATATGAAAAATGGCAGAGAA
ATGAGAGGAGGGGGATTTTT

Downstream 100 bases:

>100_bases
AAAAGCTAAGAGTTTAACTCTTAGCTTTTTTCATTAGAAAGGCTTCTAATCGGTCGCAGCCTTCTTTTAAAGTTTCGATA
CTATACGCATAGGACAAGCG

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTVTIKDVAKQANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEEEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHEQNFPFVLIGKPYDRKDEI
TYVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
LQQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAEST
AKCIIIPHKLLKRQTCDHYA

Sequences:

>Translated_340_residues
MTVTIKDVAKQANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFF
PEVIRGISSFAHVEGYALYMSTGETEEEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHEQNFPFVLIGKPYDRKDEI
TYVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
LQQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAEST
AKCIIIPHKLLKRQTCDHYA
>Mature_339_residues
TVTIKDVAKQANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTTKTLGLVMPSSASKAFQNPFFP
EVIRGISSFAHVEGYALYMSTGETEEEIFNGVVKMVQGRQIGGIILLYSRENDRIIQYLHEQNFPFVLIGKPYDRKDEIT
YVDNDNYTAAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMGL
QQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIYQLGYEAAKALVDKVENAESTA
KCIIIPHKLLKRQTCDHYA

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=33.5463258785943, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=28.6144578313253, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=28.8288288288288, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1790194, Length=315, Percent_Identity=28.5714285714286, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789068, Length=305, Percent_Identity=30.4918032786885, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=30.1369863013699, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788474, Length=339, Percent_Identity=28.6135693215339, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=28.1899109792285, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787906, Length=338, Percent_Identity=23.3727810650888, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=25.0737463126844, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994940, Length=326, Percent_Identity=25.7668711656442, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=343, Percent_Identity=26.8221574344023, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786268, Length=300, Percent_Identity=25.6666666666667, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790689, Length=339, Percent_Identity=23.8938053097345, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37509; Mature: 37378

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDVAKQANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTT
CEEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTLGLVMPSSASKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEEEIFNGVVKMVQGR
HHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLHEQNFPFVLIGKPYDRKDEITYVDNDNYTAAREVAEYLIS
CCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
LGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHC
LQQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIY
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCEEEEEHH
QLGYEAAKALVDKVENAESTAKCIIIPHKLLKRQTCDHYA
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCC
>Mature Secondary Structure 
TVTIKDVAKQANVAPSTVSRVIADNPSISEKTKRRVRKVMSELGYHPNLNARNLANQTT
EEEHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KTLGLVMPSSASKAFQNPFFPEVIRGISSFAHVEGYALYMSTGETEEEIFNGVVKMVQGR
HHHEEEECCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
QIGGIILLYSRENDRIIQYLHEQNFPFVLIGKPYDRKDEITYVDNDNYTAAREVAEYLIS
CCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
LGHKQIAFIGGGSDLLVTRDRLAGMSDALKLADIVLPKEYILHFDFSRESGQQAVEELMG
CCCCEEEEEECCCCEEEEHHHHCCHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHC
LQQPPTAIMATDDLIGLGVLSALSKKGFVVPKDVSIVSFNNALLSEIASPPLSTVDVNIY
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHCCCCCCEEEEEHH
QLGYEAAKALVDKVENAESTAKCIIIPHKLLKRQTCDHYA
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]