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The map label for this gene is comI [H]

Identifier: 218235191

GI number: 218235191

Start: 4022298

End: 4022732

Strand: Reverse

Name: comI [H]

Synonym: BCB4264_A4110

Alternate gene names: 218235191

Gene position: 4022732-4022298 (Counterclockwise)

Preceding gene: 218235962

Following gene: 218231642

Centisome position: 74.23

GC content: 39.08

Gene sequence:

>435_bases
ATGAAGCAATTAAAAGGTATTATCATTTCAATTATCGCAATTCTGTCTATTTTAGTAGCAGTTTATGAAGTACTTGTGCC
AGAGGAAACAAGTGTAAAGAAAACGAATACGTATGATCAAGTGTTAGAATTTCCGAAAGAACGTTATCCAGAGACAGGAA
AACATATTACGGATGCTATAAAAGAAGGGCATTCAGAAGTTTGTACAATCGATCGTGGTGGTGCTGCAGATAGAAGGAAA
TTGTCGTTAGCACCATATCCATCAAAAAAAGGGTATGATCGTGATGAATGGCCAATGGCGATGTGCAAGGAAGGCGGAAA
AGGAGCACATATTGAATATATAAGTCCGGCGGATAACCGTGGAGCAGGCTCTTGGGTAGGGAATAAGTTAGATAAATACC
CAGATGGTACGCGAGTAAAATTTGAAGTGAAGTAG

Upstream 100 bases:

>100_bases
GAATGGCAAGGAATAACTAAAATAATGTCTGAAAACATATACAGGAGAAGTTTGTTATAATAACGGAGGAAAAGAAACTG
GTAGAAACATGGAGGTATAC

Downstream 100 bases:

>100_bases
TAGTTGTATATTTCATAATGAAGGAGAAGGGGAACTATGGAGTTAACGATTTCTTATTCGCAATTAATGTTGATGAACTA
TGACGGTGAGCAGCCTTATG

Product: competence-specific nuclease

Products: NA

Alternate protein names: Competence-specific nuclease [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSVKKTNTYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFEVK

Sequences:

>Translated_144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSVKKTNTYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFEVK
>Mature_144_residues
MKQLKGIIISIIAILSILVAVYEVLVPEETSVKKTNTYDQVLEFPKERYPETGKHITDAIKEGHSEVCTIDRGGAADRRK
LSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNRGAGSWVGNKLDKYPDGTRVKFEVK

Specific function: By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed. Degrades both double- stranded, linear and covalently closed circular DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis nucB [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16055; Mature: 16055

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLKGIIISIIAILSILVAVYEVLVPEETSVKKTNTYDQVLEFPKERYPETGKHITDAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCHHHHHHH
KEGHSEVCTIDRGGAADRRKLSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNR
HCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCC
GAGSWVGNKLDKYPDGTRVKFEVK
CCCCHHHCHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKQLKGIIISIIAILSILVAVYEVLVPEETSVKKTNTYDQVLEFPKERYPETGKHITDAI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCCCCCHHHHHHH
KEGHSEVCTIDRGGAADRRKLSLAPYPSKKGYDRDEWPMAMCKEGGKGAHIEYISPADNR
HCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCC
GAGSWVGNKLDKYPDGTRVKFEVK
CCCCHHHCHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704255; 7746143; 8969502; 9384377; 2841296 [H]