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The map label for this gene is yvrG [H]

Identifier: 218234007

GI number: 218234007

Start: 1141053

End: 1142795

Strand: Reverse

Name: yvrG [H]

Synonym: BCB4264_A1172

Alternate gene names: 218234007

Gene position: 1142795-1141053 (Counterclockwise)

Preceding gene: 218234767

Following gene: 218232533

Centisome position: 21.09

GC content: 34.02

Gene sequence:

>1743_bases
ATGAATTTTAATAAACGACTTATTATTCAATTTATCATGCAACACGTTTTTGTTTTAGTTACATTACTTATCGCTGTAGT
TGCTGCTTTTACTTATTTAATTTTTCTTCTTACTAGTACTTTATACGAACCTAACATTCCAGATTCTGATAGTTTTACAA
TTTCAAGATACATCTCTTCAGAAGATGGGCATATTTCGTTACAATCTGAAGTGCAAGATTTAATAAAGGAGAAAAATGAT
TGGCTCCAAGTTGTAGATGAAAACGGAAAAATCCTCTACCACTTTAATACACCAAATGATGTTCCGAATGCTTATACGAA
GACATCTTTAGTCGCATATATACAACATCATATCGAAAGCAATTATAAATTTACATATTGGGAAATTGAATTAGAAGAAA
AGAAAGCACTTGTTATTTATGGTGGTATGTTAAAAAGCAATGCGTTACTTACAGCAATTCAAAAGGATCACTCCTCTTTA
ACGATGGATTCGTTCACATTAACAGATCAAGAAAAACAGTTACTGTCTAAAGAAAAAGCAGCACTTCAAATATTTAATCA
AAATGGCGAAGAGGTTTTTGCCTATCCAGCTGGAAAGAAAAAAACATTTTCAGCGATACAAATTGCCCTTAATGAAAAAG
AGCCCTGGAATCATAAAGAAAACACGTCTAGCTTTTACGATGCAAATAGTGGCAACCTTCTCGTTGTAACTGCAAAAAAT
GAGCACTACTATCCAGATGACGAAATTGAAGATGTATTTACTAAGAAGTTTCTCATTGGATGCGGATTAATCCTTCTTAT
CGTATTTGTTTATTTAGTCATTCTTTCTATTTGGTACGGTAATAAATTCGGGAAACCGTTATTACATGCGATGCGCTGGC
TTAAAAATATCGCTGGTGGAAAGTATGAAGAACCTATTAGTAAAAAAGGAAAACCTGTCAGGTTCCGGCGATCTGGTAAA
GAAAAATGGTCATTTCGTTTGTTTAGAGATGTAACAAGTTCACTAGAACACCTTTCTATTACACTCAAAAAAAATGATGC
GATGAGGCAAGTCCTCCAGCAAACACGAGAAGAATGGATTACCGGTCTAACACACGACTTAAAAACACCACTTAGCTCTA
TATATGGCTACGCATTATTACTCGAATCGAATCAATATAACTGGACTGATCGTGATATTCAGCAATTTGGTAGTGTTATG
AAAGAGAAATCTCAATATATGACGACATTAATTGATGATTTAAGCTTAACGTATCAATTAAAAAATAACAGCCTTCCTGC
TCAACACGTAAACGTTGAAATCAATCAGTTTGTCCAAAAAGTATTATTGCAATTTATTAATAATCCAACACTTCAAAATC
AAAATATTGAATTCGTACCGAGCTCAAATAAAATTCAATATTTCATTGAAGAAAAATGGTTCCAGCGTATTATCGAAAAC
TTACTAGTAAATGCTGTAAAACATAATAACGAAACAACTACTGTCATCGTAAAGTTATCACAAAACGCTAATTCCTTTAC
ACTCTCCATTTCAGATGACGGAAAAGGAATGGATGAAAAAACGAAAGAACTTCTATTTGAACGATATTACCGCGGAACAA
ACACAGAAGAAAGCAACATCGGAACTGGACTTGGCCTAGCCATTACAAAACAGCTCGTTCATGCTCATAACGGGACAATT
TCCGTTGATAGTGCACTCGGAAAAGGAACGACGATTATTCTTGTGTTTCCGTTTCGTTCGTAG

Upstream 100 bases:

>100_bases
AAAACTACGTGAAAAAATTGAACATGATCCAAGTAAACCAGAATATATAAAAACCGTTCGCGGCCTTGGTTATAAGTTCG
TTACAAAGTAGGGTGACGAT

Downstream 100 bases:

>100_bases
GAAAGACGCTATGTGGCGTCTTTTTTTCTTTTCTGGGAGAATTTCGCGGTAATTGAAATTATGCGAATCGTTTTTTTTGA
GGTGTTTTAACGGTATATGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLLTSTLYEPNIPDSDSFTISRYISSEDGHISLQSEVQDLIKEKND
WLQVVDENGKILYHFNTPNDVPNAYTKTSLVAYIQHHIESNYKFTYWEIELEEKKALVIYGGMLKSNALLTAIQKDHSSL
TMDSFTLTDQEKQLLSKEKAALQIFNQNGEEVFAYPAGKKKTFSAIQIALNEKEPWNHKENTSSFYDANSGNLLVVTAKN
EHYYPDDEIEDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPISKKGKPVRFRRSGK
EKWSFRLFRDVTSSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESNQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SVDSALGKGTTIILVFPFRS

Sequences:

>Translated_580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLLTSTLYEPNIPDSDSFTISRYISSEDGHISLQSEVQDLIKEKND
WLQVVDENGKILYHFNTPNDVPNAYTKTSLVAYIQHHIESNYKFTYWEIELEEKKALVIYGGMLKSNALLTAIQKDHSSL
TMDSFTLTDQEKQLLSKEKAALQIFNQNGEEVFAYPAGKKKTFSAIQIALNEKEPWNHKENTSSFYDANSGNLLVVTAKN
EHYYPDDEIEDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPISKKGKPVRFRRSGK
EKWSFRLFRDVTSSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESNQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SVDSALGKGTTIILVFPFRS
>Mature_580_residues
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLLTSTLYEPNIPDSDSFTISRYISSEDGHISLQSEVQDLIKEKND
WLQVVDENGKILYHFNTPNDVPNAYTKTSLVAYIQHHIESNYKFTYWEIELEEKKALVIYGGMLKSNALLTAIQKDHSSL
TMDSFTLTDQEKQLLSKEKAALQIFNQNGEEVFAYPAGKKKTFSAIQIALNEKEPWNHKENTSSFYDANSGNLLVVTAKN
EHYYPDDEIEDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPISKKGKPVRFRRSGK
EKWSFRLFRDVTSSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESNQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGTI
SVDSALGKGTTIILVFPFRS

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=26.171875, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=27.3913043478261, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=24.8979591836735, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=24.5967741935484, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=23.7068965517241, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=26.7281105990783, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=24.2063492063492, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=24.7191011235955, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=20.3030303030303, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=342, Percent_Identity=20.7602339181287, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=313, Percent_Identity=22.6837060702875, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=23.0434782608696, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=251, Percent_Identity=23.5059760956175, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=20.0873362445415, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66606; Mature: 66606

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLLTSTLYEPNIPDSDSFTISRYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
EDGHISLQSEVQDLIKEKNDWLQVVDENGKILYHFNTPNDVPNAYTKTSLVAYIQHHIES
CCCCEEEHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
NYKFTYWEIELEEKKALVIYGGMLKSNALLTAIQKDHSSLTMDSFTLTDQEKQLLSKEKA
CCEEEEEEEEECCCCEEEEECCCHHCCHHHHHHHHCCCCEEECEEEECHHHHHHHHHHHH
ALQIFNQNGEEVFAYPAGKKKTFSAIQIALNEKEPWNHKENTSSFYDANSGNLLVVTAKN
HHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
EHYYPDDEIEDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPISKKGKPVRFRRSGKEKWSFRLFRDVTSSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESNQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCHHCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGTISVDSALGKGTTIILVFPFRS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MNFNKRLIIQFIMQHVFVLVTLLIAVVAAFTYLIFLLTSTLYEPNIPDSDSFTISRYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
EDGHISLQSEVQDLIKEKNDWLQVVDENGKILYHFNTPNDVPNAYTKTSLVAYIQHHIES
CCCCEEEHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCC
NYKFTYWEIELEEKKALVIYGGMLKSNALLTAIQKDHSSLTMDSFTLTDQEKQLLSKEKA
CCEEEEEEEEECCCCEEEEECCCHHCCHHHHHHHHCCCCEEECEEEECHHHHHHHHHHHH
ALQIFNQNGEEVFAYPAGKKKTFSAIQIALNEKEPWNHKENTSSFYDANSGNLLVVTAKN
HHHHCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
EHYYPDDEIEDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPISKKGKPVRFRRSGKEKWSFRLFRDVTSSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESNQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNVEINQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCHHCCEEHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTTVIVKLSQNANSFTLSISDDGKGMDEKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGTISVDSALGKGTTIILVFPFRS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]