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The map label for this gene is helD [H]

Identifier: 218233726

GI number: 218233726

Start: 2712460

End: 2714535

Strand: Reverse

Name: helD [H]

Synonym: BCB4264_A2823

Alternate gene names: 218233726

Gene position: 2714535-2712460 (Counterclockwise)

Preceding gene: 218231755

Following gene: 218232869

Centisome position: 50.09

GC content: 34.15

Gene sequence:

>2076_bases
ATGAGCAACATATTTGAAGATGAGTTACAAAAAATGAAGGATACTTTACATACGATGGATGAGCAATTGGATAGGCTTGA
AAAAATCCCGGTTTATTATGGAGAAGATTTTAAAGAGCAAATTCTTGAAAGTATGAGGGAGTCTAATAGACAAAACTTAC
GTATTGGTGTGCAAGAGCCGTACTTTGGAAGGTTAGATTTTCAGGAAGATGGAAAAGAAGAAGTTATGCCGATTTATATC
GGAAAAGTAGGGGTTTCGGATATGGACACGATGAAGCCAATCATTATTGATTGGCGAGCGCCTGTCGCAAGTATGTTTTA
TTCATTTACCGGTGGAGAAGAATTAGCATTTTATCAATCACCAGATGGGTTAGTAGAAGGTGATGTGTATTTAAAACGAA
ACATTTCCATTCGAAAAAGAGAACTTGAACGTGTTGTTGATACATATGTAAAAGGAAATGAAGATGTATCACATGCCGAT
GATTTTCTTCTATATCGATTAGGTGAGAATAAAGATAATAAGCTAAAGGATATTGTTTCAACGATTCAATCGGAACAAAA
TGATATTATTCGAGCGGAAAGAAATTTACCATTACTTATTCAAGGGGTTGCAGGGAGTGGAAAGACAACAATTGCTTTAC
ATCGCCTTGCTTTTTTAATTTATGAATATCGTGAACAACTAGAAGCAGAAAGAATGATCGTATTTGCACCGAATAGTCTG
TTTTTAGACTATATTTCGAGTGTACTTCCTGAATTAGGTGTAGGGAATATTAGTCAAACAACGTTTCCAGATTGGGCATT
ACGTACGTTAGATGATTCAGTGAAACTAAAGCAGACAGAAAAAAAATTGAAAGAAGCATTTTCAATTAATCGTGATGAAA
AGAAGGTAATGCTAGGTAAATTAAAGGGTACGTTGGAATTTAAGACGTTTATTGAAGAGAGAATGATCCAATTTGAAAAT
GAGTTAGTTCCGACAAAAGATTTTGAGGCGTGGGATAGAGCGATTATTCCAGTAGAAGATATTAAAAAATGGATGCAAGT
TGAATATAAACATTATCCTTTACAGAAAAGAAGAGAACGATTAGTAGGACGAATGAAGCGCTGGATTGAAATTGAACTTA
AAAAATTCGGGGAAACAAACGAGAAAAAATTACTTAAAAAAGAAGCGACTAAGAGACTGAACGCATATATGAAGTTTTGG
CCGAAAATGAGTGCTCTTTCACTGTATAGTTCAATAGTAAAAAGTAAAGAAATACTTGAGGTATTCCCTGAAGAACTTGT
TAAAGAAACAGAAAAGAGTTGTCGTAAAAAAGAAGTGTGTGTAGAAGATTTACCAGCTTTAATATACATACATCATCGTA
TAACAGGGATCGAAATCGGGCAGAAGTTTCATCACGTTGTTATTGATGAAGCGCAAGATTTTTCGCCTTTCCAAGTTTAT
GTATTAAAAGAAATTACATTAGGTAATTCTTTCACTATATTAGGTGATTTATCGCAAGCGATTTATGATTACCAAGGAAT
TGAAGATTGGAATGCTTTTAAGGAAGTATTCCAAGAAACCGGTTATTATGAATTGACAAGAAGTTATCGTTCTACAAAAG
AAATTATTGAATTTGCAAATGAAATAATTAAAAATGCAGAAATCCCAGTAGGACTCGCAACACCAGTCTTCCGCAGTGGA
GAAGATGTGAAAGTAATTCATGCAGAAAATCAATTTACTGAAATTGTGAAGACGGTAAAACATTTGCAAAATGCAGATGT
GAAAACAATTGCGGTAATCGGAAGAACAGAAGATGAATGCCGTGATATATATGTGAAATTAACAAATGCAGGATTAACGG
TCAACGTAATTGAAGCAAACCAAAGTAAATATGAAGGTGGTATATCAGTAGTACCTGTCTATTTAGCGAAAGGTTTAGAA
TTTGATGCGGTGCTTTTAATTGATGTGGATGAAGAACATTACAAAAACACAAAACATGATGCAAAGTTACTATATGTCGG
ATGTACGAGATCACTTCATGACTTATGGGTTTTCCATAGTGGGGAAGCGTCACCTTTAATTAAAGGATTAAAATAA

Upstream 100 bases:

>100_bases
TTCGGAAAATTTAAATGGAAACTATTGACTTTATGATTGGATTTTTAATACAATGATACTTCGACTGAAAAATTAGAACG
GACAGGAGGGAATCGTCGAA

Downstream 100 bases:

>100_bases
AGTGGAACTATAATCAGTGGGGAGTTTTACTGCAAGCTAATGTGGGATAAATATAAAAAGAGGATTTTCTAGTACTGTAT
GAAAATCCTCTTTTTTATAT

Product: UvrD/Rep helicase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSNIFEDELQKMKDTLHTMDEQLDRLEKIPVYYGEDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSDMDTMKPIIIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTEKKLKEAFSINRDEKKVMLGKLKGTLEFKTFIEERMIQFEN
ELVPTKDFEAWDRAIIPVEDIKKWMQVEYKHYPLQKRRERLVGRMKRWIEIELKKFGETNEKKLLKKEATKRLNAYMKFW
PKMSALSLYSSIVKSKEILEVFPEELVKETEKSCRKKEVCVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWNAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSG
EDVKVIHAENQFTEIVKTVKHLQNADVKTIAVIGRTEDECRDIYVKLTNAGLTVNVIEANQSKYEGGISVVPVYLAKGLE
FDAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWVFHSGEASPLIKGLK

Sequences:

>Translated_691_residues
MSNIFEDELQKMKDTLHTMDEQLDRLEKIPVYYGEDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSDMDTMKPIIIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTEKKLKEAFSINRDEKKVMLGKLKGTLEFKTFIEERMIQFEN
ELVPTKDFEAWDRAIIPVEDIKKWMQVEYKHYPLQKRRERLVGRMKRWIEIELKKFGETNEKKLLKKEATKRLNAYMKFW
PKMSALSLYSSIVKSKEILEVFPEELVKETEKSCRKKEVCVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWNAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSG
EDVKVIHAENQFTEIVKTVKHLQNADVKTIAVIGRTEDECRDIYVKLTNAGLTVNVIEANQSKYEGGISVVPVYLAKGLE
FDAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWVFHSGEASPLIKGLK
>Mature_690_residues
SNIFEDELQKMKDTLHTMDEQLDRLEKIPVYYGEDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYIG
KVGVSDMDTMKPIIIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADD
FLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSLF
LDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTEKKLKEAFSINRDEKKVMLGKLKGTLEFKTFIEERMIQFENE
LVPTKDFEAWDRAIIPVEDIKKWMQVEYKHYPLQKRRERLVGRMKRWIEIELKKFGETNEKKLLKKEATKRLNAYMKFWP
KMSALSLYSSIVKSKEILEVFPEELVKETEKSCRKKEVCVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVYV
LKEITLGNSFTILGDLSQAIYDYQGIEDWNAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSGE
DVKVIHAENQFTEIVKTVKHLQNADVKTIAVIGRTEDECRDIYVKLTNAGLTVNVIEANQSKYEGGISVVPVYLAKGLEF
DAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWVFHSGEASPLIKGLK

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80028; Mature: 79897

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIFEDELQKMKDTLHTMDEQLDRLEKIPVYYGEDFKEQILESMRESNRQNLRIGVQEP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSDMDTMKPIIIDWRAPVASMFYSFTGGEELAFYQS
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTEKKLKEAFSINRDEKKVMLGK
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLEFKTFIEERMIQFENELVPTKDFEAWDRAIIPVEDIKKWMQVEYKHYPLQKRRER
HCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKFGETNEKKLLKKEATKRLNAYMKFWPKMSALSLYSSIVKSKEILE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFPEELVKETEKSCRKKEVCVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCEEHHHHHHHHHEECCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWNAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLATPVFRSGEDVKVIHAENQFTEIVKTVKHLQNADVKTIAVIGRTEDEC
HHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHH
RDIYVKLTNAGLTVNVIEANQSKYEGGISVVPVYLAKGLEFDAVLLIDVDEEHYKNTKHD
HEEEEEEECCCEEEEEEECCCCCCCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWVFHSGEASPLIKGLK
CEEEEEECCCCHHHEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
SNIFEDELQKMKDTLHTMDEQLDRLEKIPVYYGEDFKEQILESMRESNRQNLRIGVQEP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSDMDTMKPIIIDWRAPVASMFYSFTGGEELAFYQS
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTEKKLKEAFSINRDEKKVMLGK
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLEFKTFIEERMIQFENELVPTKDFEAWDRAIIPVEDIKKWMQVEYKHYPLQKRRER
HCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKFGETNEKKLLKKEATKRLNAYMKFWPKMSALSLYSSIVKSKEILE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFPEELVKETEKSCRKKEVCVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCEEHHHHHHHHHEECCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWNAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLATPVFRSGEDVKVIHAENQFTEIVKTVKHLQNADVKTIAVIGRTEDEC
HHHHCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHH
RDIYVKLTNAGLTVNVIEANQSKYEGGISVVPVYLAKGLEFDAVLLIDVDEEHYKNTKHD
HEEEEEEECCCEEEEEEECCCCCCCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWVFHSGEASPLIKGLK
CEEEEEECCCCHHHEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]