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The map label for this gene is nagA [H]

Identifier: 218233265

GI number: 218233265

Start: 4069830

End: 4070972

Strand: Reverse

Name: nagA [H]

Synonym: BCB4264_A4164

Alternate gene names: 218233265

Gene position: 4070972-4069830 (Counterclockwise)

Preceding gene: 218234707

Following gene: 218232087

Centisome position: 75.12

GC content: 36.48

Gene sequence:

>1143_bases
ATGAAAACGCAAATTGTCATCAATGCCAAAATTTACACAGGTCAAGAAATAGTGGAAAACGGATTTATTCGTTACGCAGA
AACCATTAAAGAAATTGGTTTGATGGCTCAATATGTACCACAAGAAAATGAAACTGTTTTTGATGCTACAGGGAAGATTG
TAATTCCAGGTATGATCGATGTTCATATTCATGGTGGATACGATATTGATGCGATGGATGCAAATAGCGATGGGTTAGTA
ACTCTAGGTAAAGAAATGTTAAAAGAAGGGGTTACAACTTACTTCCCAACAACAATGACACAAGCTCCAGAGGCAATTGA
AGCAGCGTTAACTGCTGCAAAAGAAGCAAAAGAAAAAGGAGCGCATTTCGAATATATTCACTTAGAAGGACCTTATGTTT
CAAAGAAACGTGCAGGTGCACAACCACTTGAACATATCGTTCCTGCAAATATTGAGCAATTTAAACAATGGCAAGAAGCA
AGTGGGAATTTAATTAAATTAGTAACATATGCACCAGAAGAAGAGGGAGCATTAGAGTTTGAACAATATCTTGCTGAAAC
TGGTGTAGTTGGCACAATGGGGCATACAGATGCAATTGATGGGCAACTAAAAAATAGAAAAATTACACATGCAACACATT
TATACAATCAAATGCGTGGATTACATCACCGTGAACCAGGAGTTGTTGGTCATGTGTTATTAAATCCAGATGTAATGGTT
GAAGTAATTACAGATGGTATTCATATTCACCCTGATATGGTGAAATTAGCATATAAGTTAAAAGGATCAAAAAAAGTAAG
TGTTATTACTGACGCAATGCGTGCAAAAGGTCTTGAAGATGGATTATATGAGCTTGGCGGACAGCCAGTACATGTAAAAG
ATGGTAGTGCTCGATTAGAAGATGGAACGTTAGCTGGTAGTATTCTAAAAATGGATCAAGCTTTCCGAAATGTAATTGAA
TTTACAGGTTGTTCAATCGAAGATGCAGTACTGATGACATCAGTTAACCAAGCAGAAGAGTTTGGATTAAATAATAAAGG
TGCATTAGCGGTAGGAAAAGATGCAGACTTTGTTGTGATGAATGAAGATTTACATGTATATGATACGGTTCGTTTAGGAA
TTCATATGAAGGAAGGGAAGTAA

Upstream 100 bases:

>100_bases
TTAGAATGTATAGACAACTACTCGTGTGTATATTAAGATGGAACTAGGCGAATAAGGTAATAATAACAAGTAGGTAATTC
ATGGGAAAGGATCGATGAAA

Downstream 100 bases:

>100_bases
TTAAATGAATATTCTTGTTGTAAAAACTCCAGAAGAACTAGCAGAAGCAGGTTATAAATTAATTGAAGAAGTTGTAAAAA
CAAAAGAAAATCCAACATTA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKTQIVINAKIYTGQEIVENGFIRYAETIKEIGLMAQYVPQENETVFDATGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALTAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDGQLKNRKITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGSKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Sequences:

>Translated_380_residues
MKTQIVINAKIYTGQEIVENGFIRYAETIKEIGLMAQYVPQENETVFDATGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALTAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDGQLKNRKITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGSKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK
>Mature_380_residues
MKTQIVINAKIYTGQEIVENGFIRYAETIKEIGLMAQYVPQENETVFDATGKIVIPGMIDVHIHGGYDIDAMDANSDGLV
TLGKEMLKEGVTTYFPTTMTQAPEAIEAALTAAKEAKEKGAHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEA
SGNLIKLVTYAPEEEGALEFEQYLAETGVVGTMGHTDAIDGQLKNRKITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
EVITDGIHIHPDMVKLAYKLKGSKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLEDGTLAGSILKMDQAFRNVIE
FTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVMNEDLHVYDTVRLGIHMKEGK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI224922791, Length=373, Percent_Identity=32.4396782841823, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI21361513, Length=373, Percent_Identity=32.4396782841823, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786892, Length=371, Percent_Identity=28.8409703504043, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=35.5300859598854, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19920392, Length=345, Percent_Identity=34.4927536231884, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281361140, Length=359, Percent_Identity=33.1476323119777, Blast_Score=174, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41668; Mature: 41668

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQIVINAKIYTGQEIVENGFIRYAETIKEIGLMAQYVPQENETVFDATGKIVIPGMID
CCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEE
VHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALTAAKEAKEKG
EEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
AHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGALEF
CCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
EQYLAETGVVGTMGHTDAIDGQLKNRKITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
HHHHHHCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEE
EVITDGIHIHPDMVKLAYKLKGSKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLE
EEECCCEEECHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
DGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCCCCCCEEECCCCCEEEE
NEDLHVYDTVRLGIHMKEGK
CCCEEEEEEEEEEEEEECCC
>Mature Secondary Structure
MKTQIVINAKIYTGQEIVENGFIRYAETIKEIGLMAQYVPQENETVFDATGKIVIPGMID
CCCEEEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEE
VHIHGGYDIDAMDANSDGLVTLGKEMLKEGVTTYFPTTMTQAPEAIEAALTAAKEAKEKG
EEEECCCEEEEECCCCCCEEHHHHHHHHCCCCEECCCHHHCCHHHHHHHHHHHHHHHHCC
AHFEYIHLEGPYVSKKRAGAQPLEHIVPANIEQFKQWQEASGNLIKLVTYAPEEEGALEF
CCEEEEEECCCCCCHHHCCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
EQYLAETGVVGTMGHTDAIDGQLKNRKITHATHLYNQMRGLHHREPGVVGHVLLNPDVMV
HHHHHHCCCEECCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEE
EVITDGIHIHPDMVKLAYKLKGSKKVSVITDAMRAKGLEDGLYELGGQPVHVKDGSARLE
EEECCCEEECHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCC
DGTLAGSILKMDQAFRNVIEFTGCSIEDAVLMTSVNQAEEFGLNNKGALAVGKDADFVVM
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHCCCCCCCCEEECCCCCEEEE
NEDLHVYDTVRLGIHMKEGK
CCCEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]