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The map label for this gene is nagB [H]

Identifier: 218232087

GI number: 218232087

Start: 4069037

End: 4069825

Strand: Reverse

Name: nagB [H]

Synonym: BCB4264_A4163

Alternate gene names: 218232087

Gene position: 4069825-4069037 (Counterclockwise)

Preceding gene: 218233265

Following gene: 218235367

Centisome position: 75.1

GC content: 37.64

Gene sequence:

>789_bases
ATGAATATTCTTGTTGTAAAAACTCCAGAAGAACTAGCAGAAGCAGGTTATAAATTAATTGAAGAAGTTGTAAAAACAAA
AGAAAATCCAACATTAGGAATGGCTACAGGAAGCTCTCCATTAGGTATTTATGCAGAAATGCGAAAAAATAAACTTGATA
CAAGCCGTGTAACCACTGTAAACTTAGATGAGTACGTAAATTTACCACATGAAGATAAAAACAGCTATCACTATTTCATG
CAAGAACAGTTGTTTGATCATCTTCCATTTAAACAAACTTATGTACCAAACGGGATGGCAAGTGATTTAGAGGAAGAGTG
CAAACGTTACGAGAGCATTCTAGCTGCTAACCCAGTTGACCTACAGATTCTTGGAATCGGTGAAAACGGTCACATCGGAT
TTAATGAGCCAGGAACACCGTTTAATTCTCCAACAAACATTGTTGAATTAACAGAATCTACACGCCAAGCAAACCTTCGC
TTCTTCGAAAAAGAAGAAGATGTGCCAACTCATGCGATTACAATGGGAATTGGAAGCATTATGAAAGCGAAACAAGTTCT
ACTTGTTGCTATGGGTTCTAAAAAGGCAGAAGCTGTTAAAGAATTATTGCAAGGTGAATATAGTGAAGAGTGTCCGGCTA
CAGTTTTACAACGTCATCCGAATGTAACCGTAATCGCTGATCAAGAAGCTCTATCTTTATGCAGTGAGGCGATTGCTGAT
GAACATCGACAAGTATTCACCATTTCCGATCTATTATCAGATTCAAGAGTGGGTGAAACAGCTAATTGA

Upstream 100 bases:

>100_bases
GCGGTAGGAAAAGATGCAGACTTTGTTGTGATGAATGAAGATTTACATGTATATGATACGGTTCGTTTAGGAATTCATAT
GAAGGAAGGGAAGTAATTAA

Downstream 100 bases:

>100_bases
GGACGGCGAATGGAAGCCGGGAGATAAAATCCCATCTGAGAATGAACTTTGTGATAAGTTCGAAGTGAGTCGAATGACAA
TCAGACAGGCGATTAATAAT

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYESILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQVLLVAMGSKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Sequences:

>Translated_262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYESILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQVLLVAMGSKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN
>Mature_262_residues
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFM
QEQLFDHLPFKQTYVPNGMASDLEEECKRYESILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLR
FFEKEEDVPTHAITMGIGSIMKAKQVLLVAMGSKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIAD
EHRQVFTISDLLSDSRVGETAN

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=34.5679012345679, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI19923881, Length=208, Percent_Identity=35.5769230769231, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1786893, Length=241, Percent_Identity=34.4398340248963, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1789530, Length=223, Percent_Identity=30.0448430493274, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI48994958, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=36.3636363636364, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24581960, Length=243, Percent_Identity=33.7448559670782, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI19920764, Length=243, Percent_Identity=33.7448559670782, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29103; Mature: 29103

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTV
CCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHEEEE
NLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYESILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
LQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MKAKQVLLVAMGSKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHHHHHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTV
CCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHEEEE
NLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYESILAANPVD
EHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
LQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSI
EEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MKAKQVLLVAMGSKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIAD
HHHHHHHHEECCCHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHH
EHRQVFTISDLLSDSRVGETAN
HHHEEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA