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The map label for this gene is ykoH [H]

Identifier: 218230869

GI number: 218230869

Start: 3510981

End: 3512411

Strand: Reverse

Name: ykoH [H]

Synonym: BCB4264_A3605

Alternate gene names: 218230869

Gene position: 3512411-3510981 (Counterclockwise)

Preceding gene: 218232892

Following gene: 218231447

Centisome position: 64.82

GC content: 28.93

Gene sequence:

>1431_bases
ATGGCGGTGGCAGTCATTGCTGTTACCTTAATTACAATACCCATTCAGCTACTATTTTTTATTTCTGTTGTTTTAAAAAA
TGGGGAAGAAGCGTTTAGTCATATCAAGTACAGAGCGATTCAGATTGAAAATGAAGCTTGGAGAATTGGCGGGGTTGATA
AGATACAGCAGGAATTTTTTGATGGAATTCTATTAAAAGGTGAAGAAATAAAAGTTTCATCTGCAGCAAAAAACATTGAA
TACACTTTCTACATTAAACAAAACGAAGAAGCAATAAGTAGTGTAGATAAATATTTTGCAGCCTTTTTAATAGAAACTTT
AGTTAAAAGACATCAAAAAGAAATAAATAAATTAGGTAACATATCAATTCGTAACGATGAAACAAATGGCCTTTATTATA
TGACTTATAAGCATACTTTTAAACATGGAGATAATAATGAAACGATTATAGTAAAAAGAAACGTAACACCAATTGTTATA
AAGCTAATAGAGAAATATCAAAAAGAATTTTTTATTTACTTATTGTATTTCATTATTGCTATAAGCATATTTATCTATTT
TGGGATTGGCCTAGTATTTCGCTTCTTTGGGAAAGCTCTTGATAAATCATTTGTGGAGTTAAAAGAAAAGGATTACAAGG
CTAGAATAGACATAAAGGATAGTTATGGAAAAGAAATAAGCAATGTTCAGCATCAAATCAATGATATTCTTGAGCAAATG
CAAAATCATATTGAAGTTAATATAGAGTCCATGCAGGATGTTTCACATGAGGTAAACAATAAGTTAACCTCAATTAAACA
ATCTATTGATATGCTACGATTTTACGGAACAAATAATAAACTAATTGTAGAACAAAAATTAAAGTCAATAGATGATAATA
TTGAACAAATTACAAAAGTTATGTCTACATTTCTCGATCTTGCAAAATTAGACCGGGGAATTCATATGGATGCTACAAAA
TCTCGGGATGTAAAAGAAATGATTGAGAATTACCTACAATATATAAAAAAGGTTTTTCCTGATTTTGATTTTATTGGTAA
ATATGATGTAAGCTCGCCAATTATTCATTTTAATAAAGAACATTTTGTATTAGCCTTAAATCCTATCATTGAAAATGCAG
TTAGGTATTCATTGCATAGTAATGAGATAGTCATTCATATTCGAGAAGGTAAATATTCAAACTATGTATATATTGATATT
ATTAATTGGGGTATTCAAATTGAAAAAGAGGAAATCCCACAGTTATTTAATAGATATTACAGAGGGAAGAATATTGAAAA
TTCAATGAAAGGGTTCGGAATGGGTTTAACAATATCCAAAAAAGTGATGCATTTATATAAGGGGAAAATTCATGTAAAGA
GTTATGAAGATGGCAAAAACATTTTTACATTAATCATACCCTTGCATCAGGAATCGAGAGGTGATACCTAA

Upstream 100 bases:

>100_bases
CTTGATATTGATATAATCAAAACAGTTCGAGGTAAGGGTTATGTTCTTGAAGTCTCTAGTTGCTAGAAGGATAAAAAATA
ATAAATTACATATGAAGATA

Downstream 100 bases:

>100_bases
TGGGAAATAAGATTAGGAAATTTCTCAATAATTTTGTGAAACGTGATAAACTACGTGTGCAAGTAGTTTTATTAACCCTT
ATACTTGTTCTTGTTTCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MAVAVIAVTLITIPIQLLFFISVVLKNGEEAFSHIKYRAIQIENEAWRIGGVDKIQQEFFDGILLKGEEIKVSSAAKNIE
YTFYIKQNEEAISSVDKYFAAFLIETLVKRHQKEINKLGNISIRNDETNGLYYMTYKHTFKHGDNNETIIVKRNVTPIVI
KLIEKYQKEFFIYLLYFIIAISIFIYFGIGLVFRFFGKALDKSFVELKEKDYKARIDIKDSYGKEISNVQHQINDILEQM
QNHIEVNIESMQDVSHEVNNKLTSIKQSIDMLRFYGTNNKLIVEQKLKSIDDNIEQITKVMSTFLDLAKLDRGIHMDATK
SRDVKEMIENYLQYIKKVFPDFDFIGKYDVSSPIIHFNKEHFVLALNPIIENAVRYSLHSNEIVIHIREGKYSNYVYIDI
INWGIQIEKEEIPQLFNRYYRGKNIENSMKGFGMGLTISKKVMHLYKGKIHVKSYEDGKNIFTLIIPLHQESRGDT

Sequences:

>Translated_476_residues
MAVAVIAVTLITIPIQLLFFISVVLKNGEEAFSHIKYRAIQIENEAWRIGGVDKIQQEFFDGILLKGEEIKVSSAAKNIE
YTFYIKQNEEAISSVDKYFAAFLIETLVKRHQKEINKLGNISIRNDETNGLYYMTYKHTFKHGDNNETIIVKRNVTPIVI
KLIEKYQKEFFIYLLYFIIAISIFIYFGIGLVFRFFGKALDKSFVELKEKDYKARIDIKDSYGKEISNVQHQINDILEQM
QNHIEVNIESMQDVSHEVNNKLTSIKQSIDMLRFYGTNNKLIVEQKLKSIDDNIEQITKVMSTFLDLAKLDRGIHMDATK
SRDVKEMIENYLQYIKKVFPDFDFIGKYDVSSPIIHFNKEHFVLALNPIIENAVRYSLHSNEIVIHIREGKYSNYVYIDI
INWGIQIEKEEIPQLFNRYYRGKNIENSMKGFGMGLTISKKVMHLYKGKIHVKSYEDGKNIFTLIIPLHQESRGDT
>Mature_475_residues
AVAVIAVTLITIPIQLLFFISVVLKNGEEAFSHIKYRAIQIENEAWRIGGVDKIQQEFFDGILLKGEEIKVSSAAKNIEY
TFYIKQNEEAISSVDKYFAAFLIETLVKRHQKEINKLGNISIRNDETNGLYYMTYKHTFKHGDNNETIIVKRNVTPIVIK
LIEKYQKEFFIYLLYFIIAISIFIYFGIGLVFRFFGKALDKSFVELKEKDYKARIDIKDSYGKEISNVQHQINDILEQMQ
NHIEVNIESMQDVSHEVNNKLTSIKQSIDMLRFYGTNNKLIVEQKLKSIDDNIEQITKVMSTFLDLAKLDRGIHMDATKS
RDVKEMIENYLQYIKKVFPDFDFIGKYDVSSPIIHFNKEHFVLALNPIIENAVRYSLHSNEIVIHIREGKYSNYVYIDII
NWGIQIEKEEIPQLFNRYYRGKNIENSMKGFGMGLTISKKVMHLYKGKIHVKSYEDGKNIFTLIIPLHQESRGDT

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=276, Percent_Identity=21.7391304347826, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787374, Length=304, Percent_Identity=22.0394736842105, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=24.1935483870968, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55559; Mature: 55428

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAVIAVTLITIPIQLLFFISVVLKNGEEAFSHIKYRAIQIENEAWRIGGVDKIQQEFF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEECCCHHHHHHHHH
DGILLKGEEIKVSSAAKNIEYTFYIKQNEEAISSVDKYFAAFLIETLVKRHQKEINKLGN
CCEEECCCEEEEEHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISIRNDETNGLYYMTYKHTFKHGDNNETIIVKRNVTPIVIKLIEKYQKEFFIYLLYFIIA
EEEECCCCCCEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISIFIYFGIGLVFRFFGKALDKSFVELKEKDYKARIDIKDSYGKEISNVQHQINDILEQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCHHHHHHHHHHHHHHHHH
QNHIEVNIESMQDVSHEVNNKLTSIKQSIDMLRFYGTNNKLIVEQKLKSIDDNIEQITKV
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHH
MSTFLDLAKLDRGIHMDATKSRDVKEMIENYLQYIKKVFPDFDFIGKYDVSSPIIHFNKE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
HFVLALNPIIENAVRYSLHSNEIVIHIREGKYSNYVYIDIINWGIQIEKEEIPQLFNRYY
EEEEEECHHHHHHHHHEECCCEEEEEEECCCCCCEEEEEEEECCEEECHHHHHHHHHHHH
RGKNIENSMKGFGMGLTISKKVMHLYKGKIHVKSYEDGKNIFTLIIPLHQESRGDT
CCCCCCHHHHHCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
AVAVIAVTLITIPIQLLFFISVVLKNGEEAFSHIKYRAIQIENEAWRIGGVDKIQQEFF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEEECCCEECCCHHHHHHHHH
DGILLKGEEIKVSSAAKNIEYTFYIKQNEEAISSVDKYFAAFLIETLVKRHQKEINKLGN
CCEEECCCEEEEEHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISIRNDETNGLYYMTYKHTFKHGDNNETIIVKRNVTPIVIKLIEKYQKEFFIYLLYFIIA
EEEECCCCCCEEEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ISIFIYFGIGLVFRFFGKALDKSFVELKEKDYKARIDIKDSYGKEISNVQHQINDILEQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCHHHHHHHHHHHHHHHHH
QNHIEVNIESMQDVSHEVNNKLTSIKQSIDMLRFYGTNNKLIVEQKLKSIDDNIEQITKV
HHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHH
MSTFLDLAKLDRGIHMDATKSRDVKEMIENYLQYIKKVFPDFDFIGKYDVSSPIIHFNKE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCC
HFVLALNPIIENAVRYSLHSNEIVIHIREGKYSNYVYIDIINWGIQIEKEEIPQLFNRYY
EEEEEECHHHHHHHHHEECCCEEEEEEECCCCCCEEEEEEEECCEEECHHHHHHHHHHHH
RGKNIENSMKGFGMGLTISKKVMHLYKGKIHVKSYEDGKNIFTLIIPLHQESRGDT
CCCCCCHHHHHCCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]