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The map label for this gene is arlS [H]

Identifier: 218231447

GI number: 218231447

Start: 3509452

End: 3510981

Strand: Reverse

Name: arlS [H]

Synonym: BCB4264_A3604

Alternate gene names: 218231447

Gene position: 3510981-3509452 (Counterclockwise)

Preceding gene: 218230869

Following gene: 218232989

Centisome position: 64.79

GC content: 30.65

Gene sequence:

>1530_bases
ATGGGAAATAAGATTAGGAAATTTCTCAATAATTTTGTGAAACGTGATAAACTACGTGTGCAAGTAGTTTTATTAACCCT
TATACTTGTTCTTGTTTCAGCAATACCAGTCAATTTATTTTCTATTTATAATGAGCTACAACTAACAACTCAAAGAGAAT
TTGAATCTATGTTTTCCAGGGTAGAGAAAATACAGGACAAAATAGTTTCTTCAGGAATAGGTGCATCACAGGAACTTGAT
TCTGAGTTCTTTAAGCAGATTAGCTATCCAGGTGAATCAATGAAAATTCGCATGGGTGAACAAGGAGCACAAGATTATCA
TTATGCAGCTGAGTATGAACAGAATGATAAATTTGGTATGTTTGAAGCTCAAATACTGACCTTATTCGTCCCAACCTTTT
TTGATTCTATTAAAGCACATATGAAATCACTAGATGCTACTGCTGATAAAGATAGTTATAGTTTTTATATTGATGAAAAA
AATAAAGCATATGGTGAGATTTTACATTCTTTTAAACATAAAGGTCATTATGACACGATAATCATAAAAAAAGATATAAC
ACCTAATTTGAAGATGCAAATGGTTAATAGCATGGAAAACTTCTTATATATGTTCATTTGGTTTTTCTTCTTTTCAGTTG
TGTCAGTATTAGTATGTTTAAAATTTATTTTTAAACCATTACAAAGTGCAATCGATTTAAGTTTTGAAAATGTAGTAGAT
AATAATTATCAAACAAGGATTGAAGATCCTTTGTATGGAGAAGAAATATCAAAAATTGTTCATCGTTTTAATGCAGTGTT
AGACAGGATGCATGATCTTGTACAAAACAATCTTAATTCCATGCAAGATGTATCGCATGAGATAAAGACATATCTTACGG
CAATCAAACAATCTGTTGATGTTATTAAAATATATGGAAAAAGTGATGATAAACTAGTTGCTGAAAAACTAGATGCTATT
GAAGATAATATAATTAGGGGAACGGCCATTATATCAACTACGCTGGAACTAGCCCGTTTGAAACAAATCCCAAATATTGA
TAGTGCCAATTACTATGACGTGAAATATTTAGTAAATTTCTTGTTAAGATTTAAGCAAGAAACCTATCCGAGTTTTATTT
TTGAGACAGACTATGATTCTGAAGAAGTTGAGATATTTATAGACAGGAACCATTTTTTCTTAATGATGAATCCAATTCTT
GATAATGCTGTTAAGTATTCAATGAATTCAAATATAGTTAAAATAGATACCATTTCTAAAAGAACTGATAATATGGTATA
TATTTCTATCACCAATACGGGGGTTGTTATTGATCAAAAAGAGATTCCTTTTCTCTTCGATCGTTATTATCGTGGGAAAA
ATTTGGGGAATTCAAAACAAGGATCTGGTTTAGGCTTGACCATAGCTAAAGAAGTAATGAATCTGTATAAAGGTCGAATA
ACTGTTCATGGCACAGCAGATGGAGTAACATCTTTTATATTAAGTTTTCCAAAGGCCATTAGAAGAGAAGACTCAGGAAA
TTTATCCTGA

Upstream 100 bases:

>100_bases
ATTTATATAAGGGGAAAATTCATGTAAAGAGTTATGAAGATGGCAAAAACATTTTTACATTAATCATACCCTTGCATCAG
GAATCGAGAGGTGATACCTA

Downstream 100 bases:

>100_bases
GTCTTTTTATTTTGATGGTGAGAAATAATAATTATATAGATACATTAATCTTAGGTGGCAAAGTATTTGTTGGAGTAATT
TGAAAAATAATTTTTGGGGA

Product: sensor histidine kinase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MGNKIRKFLNNFVKRDKLRVQVVLLTLILVLVSAIPVNLFSIYNELQLTTQREFESMFSRVEKIQDKIVSSGIGASQELD
SEFFKQISYPGESMKIRMGEQGAQDYHYAAEYEQNDKFGMFEAQILTLFVPTFFDSIKAHMKSLDATADKDSYSFYIDEK
NKAYGEILHSFKHKGHYDTIIIKKDITPNLKMQMVNSMENFLYMFIWFFFFSVVSVLVCLKFIFKPLQSAIDLSFENVVD
NNYQTRIEDPLYGEEISKIVHRFNAVLDRMHDLVQNNLNSMQDVSHEIKTYLTAIKQSVDVIKIYGKSDDKLVAEKLDAI
EDNIIRGTAIISTTLELARLKQIPNIDSANYYDVKYLVNFLLRFKQETYPSFIFETDYDSEEVEIFIDRNHFFLMMNPIL
DNAVKYSMNSNIVKIDTISKRTDNMVYISITNTGVVIDQKEIPFLFDRYYRGKNLGNSKQGSGLGLTIAKEVMNLYKGRI
TVHGTADGVTSFILSFPKAIRREDSGNLS

Sequences:

>Translated_509_residues
MGNKIRKFLNNFVKRDKLRVQVVLLTLILVLVSAIPVNLFSIYNELQLTTQREFESMFSRVEKIQDKIVSSGIGASQELD
SEFFKQISYPGESMKIRMGEQGAQDYHYAAEYEQNDKFGMFEAQILTLFVPTFFDSIKAHMKSLDATADKDSYSFYIDEK
NKAYGEILHSFKHKGHYDTIIIKKDITPNLKMQMVNSMENFLYMFIWFFFFSVVSVLVCLKFIFKPLQSAIDLSFENVVD
NNYQTRIEDPLYGEEISKIVHRFNAVLDRMHDLVQNNLNSMQDVSHEIKTYLTAIKQSVDVIKIYGKSDDKLVAEKLDAI
EDNIIRGTAIISTTLELARLKQIPNIDSANYYDVKYLVNFLLRFKQETYPSFIFETDYDSEEVEIFIDRNHFFLMMNPIL
DNAVKYSMNSNIVKIDTISKRTDNMVYISITNTGVVIDQKEIPFLFDRYYRGKNLGNSKQGSGLGLTIAKEVMNLYKGRI
TVHGTADGVTSFILSFPKAIRREDSGNLS
>Mature_508_residues
GNKIRKFLNNFVKRDKLRVQVVLLTLILVLVSAIPVNLFSIYNELQLTTQREFESMFSRVEKIQDKIVSSGIGASQELDS
EFFKQISYPGESMKIRMGEQGAQDYHYAAEYEQNDKFGMFEAQILTLFVPTFFDSIKAHMKSLDATADKDSYSFYIDEKN
KAYGEILHSFKHKGHYDTIIIKKDITPNLKMQMVNSMENFLYMFIWFFFFSVVSVLVCLKFIFKPLQSAIDLSFENVVDN
NYQTRIEDPLYGEEISKIVHRFNAVLDRMHDLVQNNLNSMQDVSHEIKTYLTAIKQSVDVIKIYGKSDDKLVAEKLDAIE
DNIIRGTAIISTTLELARLKQIPNIDSANYYDVKYLVNFLLRFKQETYPSFIFETDYDSEEVEIFIDRNHFFLMMNPILD
NAVKYSMNSNIVKIDTISKRTDNMVYISITNTGVVIDQKEIPFLFDRYYRGKNLGNSKQGSGLGLTIAKEVMNLYKGRIT
VHGTADGVTSFILSFPKAIRREDSGNLS

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=23.8853503184713, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=306, Percent_Identity=21.8954248366013, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58777; Mature: 58646

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GNKIRKFLNNFVKRDKLRVQVVLLTLILVLVSAIPVNLFSIYNELQLTTQREFESMFSR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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EEEECHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA