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The map label for this gene is arlR [H]

Identifier: 218232892

GI number: 218232892

Start: 3512446

End: 3513153

Strand: Reverse

Name: arlR [H]

Synonym: BCB4264_A3606

Alternate gene names: 218232892

Gene position: 3513153-3512446 (Counterclockwise)

Preceding gene: 218232115

Following gene: 218230869

Centisome position: 64.83

GC content: 32.06

Gene sequence:

>708_bases
TTGTACAGATTATTATTACTTGAAGATGAAGTTGAAATCGGTAGCACACTTGAAATGATTTTAAGAAGCGAAAATTATCA
TATTGATTGGTTTACTACTGGTGATGAAGCAGTGAATGCTGCTGTATCTAATGATTATGACTTAATGATATTAGATGTCA
TGTTAAAGAAAACAGTGGGAGAGTTAAATACTCGTATTTCAAATGGCCTTGAAGTTGCAAGGTTAGTGAATCAAAAAAAG
AAAATTCCATATTTACTCCTGACATCAAGAAGCGAACCGCTAGATATTATGCAAGGCTTAGATATGGGAGCAGAAGACTA
TATAACAAAACCATATGACTTAACGGTGTTGCTTGCGAGAATCCGAACAGTTTTAAGAAGAAGTTATAGTAACGATATTT
CTAACGGAGGAATTACTCGATGCGGTAATATTGAGATTAATTTATTAACGCACAAAGTAATTGTTGAGGGTAAGCATGTT
CATTTAACTAAACAACTTTTCGAATTATTACATTACTTCATCATTCATAAGGGACAAATTATTTCTAAAGAAGAATTATA
TAAAAATATTTGGGGATATGATCCTTCAGAACTTCAAGAAACAAATACTCTGGAAGTAAATATCCGTAGGTTAAGAAATT
CACTTGATATTGATATAATCAAAACAGTTCGAGGTAAGGGTTATGTTCTTGAAGTCTCTAGTTGCTAG

Upstream 100 bases:

>100_bases
AAGATAAACGAATTCACTGCTTAATTTCGCCTTCTAACAGGGGATTTTTTGCGTTGTTTTCAAACATTTCGCACTTAAAA
GACCTGTGGGAGGGAGAAAA

Downstream 100 bases:

>100_bases
AAGGATAAAAAATAATAAATTACATATGAAGATAATGGCGGTGGCAGTCATTGCTGTTACCTTAATTACAATACCCATTC
AGCTACTATTTTTTATTTCT

Product: transcriptional activator protein CopR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MYRLLLLEDEVEIGSTLEMILRSENYHIDWFTTGDEAVNAAVSNDYDLMILDVMLKKTVGELNTRISNGLEVARLVNQKK
KIPYLLLTSRSEPLDIMQGLDMGAEDYITKPYDLTVLLARIRTVLRRSYSNDISNGGITRCGNIEINLLTHKVIVEGKHV
HLTKQLFELLHYFIIHKGQIISKEELYKNIWGYDPSELQETNTLEVNIRRLRNSLDIDIIKTVRGKGYVLEVSSC

Sequences:

>Translated_235_residues
MYRLLLLEDEVEIGSTLEMILRSENYHIDWFTTGDEAVNAAVSNDYDLMILDVMLKKTVGELNTRISNGLEVARLVNQKK
KIPYLLLTSRSEPLDIMQGLDMGAEDYITKPYDLTVLLARIRTVLRRSYSNDISNGGITRCGNIEINLLTHKVIVEGKHV
HLTKQLFELLHYFIIHKGQIISKEELYKNIWGYDPSELQETNTLEVNIRRLRNSLDIDIIKTVRGKGYVLEVSSC
>Mature_235_residues
MYRLLLLEDEVEIGSTLEMILRSENYHIDWFTTGDEAVNAAVSNDYDLMILDVMLKKTVGELNTRISNGLEVARLVNQKK
KIPYLLLTSRSEPLDIMQGLDMGAEDYITKPYDLTVLLARIRTVLRRSYSNDISNGGITRCGNIEINLLTHKVIVEGKHV
HLTKQLFELLHYFIIHKGQIISKEELYKNIWGYDPSELQETNTLEVNIRRLRNSLDIDIIKTVRGKGYVLEVSSC

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=236, Percent_Identity=33.4745762711864, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=34.3347639484979, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=30.0429184549356, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.304347826087, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=30.1724137931034, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=31.7596566523605, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789809, Length=240, Percent_Identity=29.1666666666667, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=238, Percent_Identity=27.7310924369748, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1788394, Length=244, Percent_Identity=29.9180327868852, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=244, Percent_Identity=27.4590163934426, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=28.6324786324786, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=29.1139240506329, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787375, Length=235, Percent_Identity=25.1063829787234, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27000; Mature: 27000

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRLLLLEDEVEIGSTLEMILRSENYHIDWFTTGDEAVNAAVSNDYDLMILDVMLKKTVG
CEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHH
ELNTRISNGLEVARLVNQKKKIPYLLLTSRSEPLDIMQGLDMGAEDYITKPYDLTVLLAR
HHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHCCCCHHHHHHHHH
IRTVLRRSYSNDISNGGITRCGNIEINLLTHKVIVEGKHVHLTKQLFELLHYFIIHKGQI
HHHHHHHHHCCCCCCCCCEEECCEEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHCCCCE
ISKEELYKNIWGYDPSELQETNTLEVNIRRLRNSLDIDIIKTVRGKGYVLEVSSC
ECHHHHHHHHCCCCHHHHCCCCCCEEEHHHHHCCCCEEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MYRLLLLEDEVEIGSTLEMILRSENYHIDWFTTGDEAVNAAVSNDYDLMILDVMLKKTVG
CEEEEEEECCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHH
ELNTRISNGLEVARLVNQKKKIPYLLLTSRSEPLDIMQGLDMGAEDYITKPYDLTVLLAR
HHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCHHHCCCCHHHHHHHHH
IRTVLRRSYSNDISNGGITRCGNIEINLLTHKVIVEGKHVHLTKQLFELLHYFIIHKGQI
HHHHHHHHHCCCCCCCCCEEECCEEEEEEEEEEEECCCEEHHHHHHHHHHHHHHHCCCCE
ISKEELYKNIWGYDPSELQETNTLEVNIRRLRNSLDIDIIKTVRGKGYVLEVSSC
ECHHHHHHHHCCCCHHHHCCCCCCEEEHHHHHCCCCEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA