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The map label for this gene is frdB [H]

Identifier: 21674851

GI number: 21674851

Start: 1939149

End: 1940186

Strand: Reverse

Name: frdB [H]

Synonym: CT2041

Alternate gene names: 21674851

Gene position: 1940186-1939149 (Counterclockwise)

Preceding gene: 21674852

Following gene: 21674850

Centisome position: 90.03

GC content: 56.65

Gene sequence:

>1038_bases
ATGAGCGATTCAACGATACAGCATCATGAGGAGAGCCGGGATGTAACCTTCAGGGTTCACCGGTTCAATCCCCAGGTTGA
CAGCAAGCCCTATTTCGATGACTACACGATCAAGCTCGAAAAAGGTATCACCGTGCTCAGGGCTCTCAACTATATCAAGG
AGCATGTCGATTCGACGCTGACCTTCAGGGCTTTCTGTCAGGCCGGTATCTGCGGCTCCTGCGCCATGAGGATCAACAAC
ATGTCGAAGCTCGCCTGCACCACCCAGGTCTGGGACGAGCTCGAAAAGGCCCGCGAACCGGGTGTCATCAAGATCGAGCC
GCTTCGGAATCTGCCGCACATCAAAGATCTGGTGGTCGAGATGGACCCGGTGGTTGGCAAGATGAAGAAGTATTCCAACT
GGGTGGTTTCCCGGATGCCGGAAGAGCAGTGGGGGAAGAAGGAGTTCCTCATTTCCGAGGAGGAGTTCCAGACCTACGAC
AAGGCGACCGACTGTATTCTTTGCGCTTCGTGTGTTTCGGAGTGCACTATACTTCGGGCGCACAAGGAGTATGTTTCTCC
CGTCGTGCTGCTCAGGTCGTACCGTATGAATGCTGACAGCCGCGACGGCATTCACGACCAGCGTCTGGCGGATCTCGTGC
AGGATCACGGGGTGTGGGATTGCACGCACTGCTACCGCTGCCAGGAGACCTGCGTCAAGAACATTCCGATCATGGACGCC
ATCCACGGCCTCAGGGAAGATGCCATCGAGCGCCGGGGCACCAAGGATACCAGCGGTGCCCGCCATGCCGAGGCTTTCAT
GGATGATATCGAGAAAAAGGGCAAGCTGGTCGAGGCCACCCTGCCGATCAGGACCAATGGCATCGCCTGGACGCTCAAGA
ACCTGCTTCCGATGGCCGTCAAGATGATCATCAAGCGTCGAACCCCGCCGCCGCCGCCGCTGGTCAAGGCGTCCAAGGGC
ATTCAGTCCCTGCGCAAGGAGATGAAGGAGATGGCCAGCCATATAACGAAGGATCACGAAAAAAAATCCGGAGAATAA

Upstream 100 bases:

>100_bases
TTATACATACGAGAATGGCCGCCCGAAGCTTGCATACAAACCGGTCACGATGGGCCGCTACGAGCTTCAGGAACGAACCT
ATTAATCCGAAGGATTTTCA

Downstream 100 bases:

>100_bases
GCAGTATGAAGCGTTACGCCTACTATCAGAGCTGCATCAATGAAGCGATGACCAAAGAGGTCGATCGGTCGCTTGGCCTC
TGGCAGCATGATCTTGGCAT

Product: succinate/fumarate oxidoreductase, iron-sulfur protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSDSTIQHHEESRDVTFRVHRFNPQVDSKPYFDDYTIKLEKGITVLRALNYIKEHVDSTLTFRAFCQAGICGSCAMRINN
MSKLACTTQVWDELEKAREPGVIKIEPLRNLPHIKDLVVEMDPVVGKMKKYSNWVVSRMPEEQWGKKEFLISEEEFQTYD
KATDCILCASCVSECTILRAHKEYVSPVVLLRSYRMNADSRDGIHDQRLADLVQDHGVWDCTHCYRCQETCVKNIPIMDA
IHGLREDAIERRGTKDTSGARHAEAFMDDIEKKGKLVEATLPIRTNGIAWTLKNLLPMAVKMIIKRRTPPPPPLVKASKG
IQSLRKEMKEMASHITKDHEKKSGE

Sequences:

>Translated_345_residues
MSDSTIQHHEESRDVTFRVHRFNPQVDSKPYFDDYTIKLEKGITVLRALNYIKEHVDSTLTFRAFCQAGICGSCAMRINN
MSKLACTTQVWDELEKAREPGVIKIEPLRNLPHIKDLVVEMDPVVGKMKKYSNWVVSRMPEEQWGKKEFLISEEEFQTYD
KATDCILCASCVSECTILRAHKEYVSPVVLLRSYRMNADSRDGIHDQRLADLVQDHGVWDCTHCYRCQETCVKNIPIMDA
IHGLREDAIERRGTKDTSGARHAEAFMDDIEKKGKLVEATLPIRTNGIAWTLKNLLPMAVKMIIKRRTPPPPPLVKASKG
IQSLRKEMKEMASHITKDHEKKSGE
>Mature_344_residues
SDSTIQHHEESRDVTFRVHRFNPQVDSKPYFDDYTIKLEKGITVLRALNYIKEHVDSTLTFRAFCQAGICGSCAMRINNM
SKLACTTQVWDELEKAREPGVIKIEPLRNLPHIKDLVVEMDPVVGKMKKYSNWVVSRMPEEQWGKKEFLISEEEFQTYDK
ATDCILCASCVSECTILRAHKEYVSPVVLLRSYRMNADSRDGIHDQRLADLVQDHGVWDCTHCYRCQETCVKNIPIMDAI
HGLREDAIERRGTKDTSGARHAEAFMDDIEKKGKLVEATLPIRTNGIAWTLKNLLPMAVKMIIKRRTPPPPPLVKASKGI
QSLRKEMKEMASHITKDHEKKSGE

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=233, Percent_Identity=37.7682403433476, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=30.6034482758621, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786943, Length=241, Percent_Identity=31.9502074688797, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17533915, Length=238, Percent_Identity=33.1932773109244, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322987, Length=224, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137106, Length=241, Percent_Identity=34.0248962655602, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24643156, Length=239, Percent_Identity=33.0543933054393, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 39529; Mature: 39398

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSTIQHHEESRDVTFRVHRFNPQVDSKPYFDDYTIKLEKGITVLRALNYIKEHVDSTL
CCCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHH
TFRAFCQAGICGSCAMRINNMSKLACTTQVWDELEKAREPGVIKIEPLRNLPHIKDLVVE
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
MDPVVGKMKKYSNWVVSRMPEEQWGKKEFLISEEEFQTYDKATDCILCASCVSECTILRA
HHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKEYVSPVVLLRSYRMNADSRDGIHDQRLADLVQDHGVWDCTHCYRCQETCVKNIPIMDA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHH
IHGLREDAIERRGTKDTSGARHAEAFMDDIEKKGKLVEATLPIRTNGIAWTLKNLLPMAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCHHHHHHHHHHHHH
KMIIKRRTPPPPPLVKASKGIQSLRKEMKEMASHITKDHEKKSGE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDSTIQHHEESRDVTFRVHRFNPQVDSKPYFDDYTIKLEKGITVLRALNYIKEHVDSTL
CCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHH
TFRAFCQAGICGSCAMRINNMSKLACTTQVWDELEKAREPGVIKIEPLRNLPHIKDLVVE
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHH
MDPVVGKMKKYSNWVVSRMPEEQWGKKEFLISEEEFQTYDKATDCILCASCVSECTILRA
HHHHHHHHHHHHHHHHHCCCHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKEYVSPVVLLRSYRMNADSRDGIHDQRLADLVQDHGVWDCTHCYRCQETCVKNIPIMDA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHH
IHGLREDAIERRGTKDTSGARHAEAFMDDIEKKGKLVEATLPIRTNGIAWTLKNLLPMAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCEECCCHHHHHHHHHHHHH
KMIIKRRTPPPPPLVKASKGIQSLRKEMKEMASHITKDHEKKSGE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]