Click here to switch to the map view.

The map label for this gene is folB [H]

Identifier: 21674749

GI number: 21674749

Start: 1831135

End: 1831515

Strand: Direct

Name: folB [H]

Synonym: CT1937

Alternate gene names: 21674749

Gene position: 1831135-1831515 (Clockwise)

Preceding gene: 21674746

Following gene: 21674750

Centisome position: 84.97

GC content: 57.22

Gene sequence:

>381_bases
ATGAAGCTTCATCATCGTTCCTGTATCAGGCTTGTCAACGCCGTTTTTTACGCCCGGCACGGTGTCCACGAAGAGGAACG
CCGTCTTGGCGGACGGTATGAGGTCGATGCCGAGCTTTTTTTTGACAGCACTGAGGCCGCCGCTGCCGATGATCTCTTGA
AAACCATCGATTACGGGCAGGCATATACCATCATCAGCGAGGTTATGATTGCTGGTGAACCGGCGGCACTCATCGAGACG
CTGGCCGCAAGAGCCGCCGCAAGGCTGATTGAGGAGCTGGCCCTCGCGGAGAAAGTCACCGTGAAGGTGCGCAAGCGAGC
GCTGCCTCTCGGCGGGCTGTGCGATTATGCTGAAGCCGAACACGTGATTGAAAGGCACTGA

Upstream 100 bases:

>100_bases
GCCATTTATACCGGCTGTCAGGAACCGTTTTGCAATGAAGTTGCGAATAGGTTACATTCTTGCAGATTCCTCCTGAATAC
TGATCTCTCGCCGCGCGACC

Downstream 100 bases:

>100_bases
ACAATGGCGCCAGTTACCGCCTATATCGGCATCGGCTCGAATGTCGGAGACCGGCTCGGCTACCTTCAGCAGGCCGTTGA
CCACCTTGCACAACTGCCTG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKLHHRSCIRLVNAVFYARHGVHEEERRLGGRYEVDAELFFDSTEAAAADDLLKTIDYGQAYTIISEVMIAGEPAALIET
LAARAAARLIEELALAEKVTVKVRKRALPLGGLCDYAEAEHVIERH

Sequences:

>Translated_126_residues
MKLHHRSCIRLVNAVFYARHGVHEEERRLGGRYEVDAELFFDSTEAAAADDLLKTIDYGQAYTIISEVMIAGEPAALIET
LAARAAARLIEELALAEKVTVKVRKRALPLGGLCDYAEAEHVIERH
>Mature_126_residues
MKLHHRSCIRLVNAVFYARHGVHEEERRLGGRYEVDAELFFDSTEAAAADDLLKTIDYGQAYTIISEVMIAGEPAALIET
LAARAAARLIEELALAEKVTVKVRKRALPLGGLCDYAEAEHVIERH

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14030; Mature: 14030

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHHRSCIRLVNAVFYARHGVHEEERRLGGRYEVDAELFFDSTEAAAADDLLKTIDYGQ
CCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCH
AYTIISEVMIAGEPAALIETLAARAAARLIEELALAEKVTVKVRKRALPLGGLCDYAEAE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
HVIERH
HHHHCC
>Mature Secondary Structure
MKLHHRSCIRLVNAVFYARHGVHEEERRLGGRYEVDAELFFDSTEAAAADDLLKTIDYGQ
CCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCH
AYTIISEVMIAGEPAALIETLAARAAARLIEELALAEKVTVKVRKRALPLGGLCDYAEAE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
HVIERH
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]