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The map label for this gene is engA

Identifier: 21674598

GI number: 21674598

Start: 1689169

End: 1690482

Strand: Direct

Name: engA

Synonym: CT1784

Alternate gene names: 21674598

Gene position: 1689169-1690482 (Clockwise)

Preceding gene: 21674592

Following gene: 21674599

Centisome position: 78.39

GC content: 59.21

Gene sequence:

>1314_bases
ATGAAACCACTGATCGCCCTGGTAGGTCGGCCCAACGTCGGCAAATCGACCCTTTTTAACCGCATTCTCAGGCAGAAAAG
CGCCATCGTCGATCCCACGCCGGGCGTGACCCGGGACCGCCACATCAGCCCCGGCGAGTGGCAGGGCAAGCAGTTTTTGC
TCATGGACACCGGCGGCTACGCACCCGAAAACGACACGCTCAGCAAGGCGATGCTCGAACAGACCATGCGCGCCATCGAG
GATGCCGATGCGGTGATCTTCATAGTGGACGCCCGCTCCGGGTTGACCTATCTCGACCTCGACATCGCAAAGATTCTCCA
GAAGACCTTCAAGGACAAGAAAATCTTTTTTGTGGCCAACAAGGTGGATAATCCACAGGTCGCGCTCGAAGCTCAGTCGC
TGGTCAAAAGCGGCTTTACCGAACCCTATCTCATCTCGGCGCGCGACGGCGCTGGCGTGGCCGACATGCTCGAAGACGTT
CTCAACTCGCTGCCATGCCCGGAGGGTGAGGAGATCGAAGAGGACGACTCGATCAAGCTCGCCGTGCTCGGGCGGCCGAA
CGTCGGCAAGTCGAGCCTGGTCAACGCCCTGCTCGGCACTGAACGGCACATCGTCTCGGACGTGCCCGGCACCACGCGCG
ACGCCATCGACTCGGTGCTGAAACGCAACGGCGAGGAGTACGTGCTGATCGACACGGCTGGCCTGCGCAAGCGCACGAAA
ATCGACGCCGGCATCGAGTTCTACAGCTCGCTCCGCACGGCTCGCGCCATCGAACGCTGCGACGTGGCGCTGGTGCTGCT
CGACGCCCGGCTCGGCCTCGAAAGCCAGGACATGAAGATCATCCACATGGCCATCGAGCGCAAAAAGGGCGTGCTGATTC
TGGTCAACAAATGGGATCTGGTCGAGAAGGACTCCAAAACCAGCAAGGCATTCACCGACAACCTGCAAAACCAGCTCGGC
AACATCGGGTACATTCCGGTGATCTTCACCTCGGCCTTGACAAAGAAGAACTGCTACCGTGCCATCGACACCGCTGCGGA
GATCGCGCTGAACCGTCGACAGAAGATCAGCACCAGCAACCTGAACCGTTTTTTGCAGGAGACGCTCACCATGCGCCACC
CGGCGACCAAATCGGGCAAGGAGCTGAAAATCAAGTACATGACGCAGATCGACTCGGACCATCCGGTTTTCGCCTTCTTC
TGCAACGACCCGGAGCTGCTCGAAAACAACTTCCGTCGCTTCCTCGAAAAACGCCTGCGCGAGAGCTTCGACTTTGCAGG
CATTCCGATCACCATGCGCTTTCTACGGAAATGA

Upstream 100 bases:

>100_bases
TAATTTATTCCAATTAATTCTACAAACTATTACCTTGTTCTCTTTGCAAGAAGTTATTCAAACCGAAAACGTCCGACAGA
CGTTCTCACGCCGCTTAGAG

Downstream 100 bases:

>100_bases
GCCCGGGAACCGCCTGGCGTAAAGCGCAGTTCTTGTAACGGCTTTAACCAAGGCGGTGCTGGCTGACCAAACTGATCACA
CAAATCCGATTAATCTAAAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGYAPENDTLSKAMLEQTMRAIE
DADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVANKVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDV
LNSLPCPEGEEIEEDDSIKLAVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTK
IDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKAFTDNLQNQLG
NIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSNLNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFF
CNDPELLENNFRRFLEKRLRESFDFAGIPITMRFLRK

Sequences:

>Translated_437_residues
MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGYAPENDTLSKAMLEQTMRAIE
DADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVANKVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDV
LNSLPCPEGEEIEEDDSIKLAVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTK
IDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKAFTDNLQNQLG
NIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSNLNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFF
CNDPELLENNFRRFLEKRLRESFDFAGIPITMRFLRK
>Mature_437_residues
MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGYAPENDTLSKAMLEQTMRAIE
DADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVANKVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDV
LNSLPCPEGEEIEEDDSIKLAVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTK
IDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKAFTDNLQNQLG
NIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSNLNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFF
CNDPELLENNFRRFLEKRLRESFDFAGIPITMRFLRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=38.6266094420601, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI2367268, Length=245, Percent_Identity=27.3469387755102, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788919, Length=125, Percent_Identity=35.2, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=186, Percent_Identity=31.7204301075269, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=36.9942196531792, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHLTE (Q8KBK3)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662663.1
- ProteinModelPortal:   Q8KBK3
- SMR:   Q8KBK3
- GeneID:   1008192
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1784
- NMPDR:   fig|194439.1.peg.1757
- TIGR:   CT1784
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   CTEP194439:CT_1784-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48978; Mature: 48978

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
APENDTLSKAMLEQTMRAIEDADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVAN
CCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEEE
KVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDVLNSLPCPEGEEIEEDDSIKL
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEE
AVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTK
EEECCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDL
HHHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCHHEEEEEHHCCCCEEEEEECCCC
VEKDSKTSKAFTDNLQNQLGNIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSN
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFFCNDPELLENNFRRFLEKRLR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
ESFDFAGIPITMRFLRK
HHCCCCCCCHHHHHHCC
>Mature Secondary Structure
MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
APENDTLSKAMLEQTMRAIEDADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVAN
CCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEHHHHHHHHHHHCCCCEEEEEEE
KVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDVLNSLPCPEGEEIEEDDSIKL
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEE
AVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTK
EEECCCCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
IDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDL
HHHHHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCCCCHHEEEEEHHCCCCEEEEEECCCC
VEKDSKTSKAFTDNLQNQLGNIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSN
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFFCNDPELLENNFRRFLEKRLR
HHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHH
ESFDFAGIPITMRFLRK
HHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901