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The map label for this gene is yacO [H]

Identifier: 21674445

GI number: 21674445

Start: 1533414

End: 1534187

Strand: Reverse

Name: yacO [H]

Synonym: CT1627

Alternate gene names: 21674445

Gene position: 1534187-1533414 (Counterclockwise)

Preceding gene: 21674447

Following gene: 21674444

Centisome position: 71.19

GC content: 59.69

Gene sequence:

>774_bases
TTGAACAGAAAAGATCACGCCGAAATACCGGCTCAAAAACCTCGTGAGCAGGTCGTCTATGGCCGCAACGCTGTCATCGA
GCTGTTGCAGTCGAAACCTGAGAGCGTCGAGAAGATATACCTCCAGTTCAATACCTCCCATCCCAAGCTCAAGGAGATTG
TTATCACGGCCCGCAGGCTCAGGATTCCTTGCGGCAAAGCGCGTATGGAGAAGCTCACGCTTCTTTCCGGTACCGCCAAG
AACCAGGGGGTCTGTGCTCTTCTGACCAGCGTAACCTTTTACACGCTCAACGAGGTGCTCGCCGCGCCGCGCAACAGTTC
GCCGCTCTTGGTGATTTTGCAGGGGCTCGAAGACCCGCATAACGTTGGGGCGATTATCCGCACCGCCGAGGCCGTGGCCG
CCGATGCAGTCATCATGATCGAGGGCAAGGGGGCGCCGATCAGCGCCACAGTGCACAAAGCCTCGGCGGGTGCGCTGTCG
CACATGCGCGTCTGCAAGGTCAAAAGCGTGGTTAAGGCGCTTGACCTGTTGCGCGAACGCGGATTCAGCATCGTAGCCGC
CGACATGGAGGCCGAGCATAACCACACCGACATCGACTGGAAGCGCCCGACGGTGCTTGTCATGGGCGCAGAGGGCAGCG
GTCTTGGCTCTGAAACCCGCAATCGCTGCGACCAGATCGTGCGAATCCCTATGGCTGGTTGCGTCGAATCGCTCAACGTC
AGCGTGGCTGCGGGCGTGATGCTCTACGAAGCGATGCGGCAGCGCCTGGGTTGA

Upstream 100 bases:

>100_bases
AATCGTGAGTACTATTTATAGCCTTTGCTCGCTGATACGTATTTTTTGCATCTGACGAGCGGTCGGAACGCATTTCCAGC
AAACCAAACTTTCCTGATTT

Downstream 100 bases:

>100_bases
AGAGAAGAGCCGTCTGATTCGGTCGATCTTTTCTTCTCCTGAAAAAATGTTATTTTAAAGTTCATTTGTATTCCTTCCTC
AATTGCATAGCAACCTAAAT

Product: SpoU rRNA methylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNRKDHAEIPAQKPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLRIPCGKARMEKLTLLSGTAK
NQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADAVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSVVKALDLLRERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG

Sequences:

>Translated_257_residues
MNRKDHAEIPAQKPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLRIPCGKARMEKLTLLSGTAK
NQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADAVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSVVKALDLLRERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG
>Mature_257_residues
MNRKDHAEIPAQKPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLRIPCGKARMEKLTLLSGTAK
NQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADAVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSVVKALDLLRERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=262, Percent_Identity=29.7709923664122, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1790623, Length=241, Percent_Identity=34.4398340248963, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790083, Length=159, Percent_Identity=38.9937106918239, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788935, Length=243, Percent_Identity=28.3950617283951, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17555908, Length=251, Percent_Identity=26.6932270916335, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=28.4848484848485, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27924; Mature: 27924

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKDHAEIPAQKPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRL
CCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCHHHEEEEEEEECCCCHHHHHHHHHHHH
RIPCGKARMEKLTLLSGTAKNQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPH
CCCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
NVGAIIRTAEAVAADAVIMIEGKGAPISATVHKASAGALSHMRVCKVKSVVKALDLLRER
HHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNV
CCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCH
SVAAGVMLYEAMRQRLG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRKDHAEIPAQKPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRL
CCCCCCCCCCCCCCHHHHHHCHHHHHHHHHCCCHHHEEEEEEEECCCCHHHHHHHHHHHH
RIPCGKARMEKLTLLSGTAKNQGVCALLTSVTFYTLNEVLAAPRNSSPLLVILQGLEDPH
CCCCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
NVGAIIRTAEAVAADAVIMIEGKGAPISATVHKASAGALSHMRVCKVKSVVKALDLLRER
HHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGSGLGSETRNRCDQIVRIPMAGCVESLNV
CCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCH
SVAAGVMLYEAMRQRLG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]