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The map label for this gene is lnt

Identifier: 21674318

GI number: 21674318

Start: 1402230

End: 1403831

Strand: Reverse

Name: lnt

Synonym: CT1498

Alternate gene names: 21674318

Gene position: 1403831-1402230 (Counterclockwise)

Preceding gene: 21674320

Following gene: 21674315

Centisome position: 65.14

GC content: 54.87

Gene sequence:

>1602_bases
ATGAATGGCGCTTATAGAGGCGCCTTGTCTCGTTTACTTTCGAAACCTTTTTTTCTGCCGCTCCTGAGCGGCCTGCTCCT
CGGGATATCCTTTCCGACCTGGCCTGCCGTCCATCTCGAACCTCTTGCATGGATAGCTCTGGTGCCGTTATTGCTTTCAC
TTGAACACGAAGAACGTTTTGGCCCTTTTTTCAGAAAGAGCTGGATGTCGATGCTTTTGTTCTGTCTTATCGCGCTCTGG
TGGGTATGCCTCGCAACCTTTGTTGGCGGCATTCTCACCGTGTTTGTGCAGTCTCTTTTTTCAGTCGTGCCGTTGGTGGT
GTTCTACTATTTCAAGAAAAGAGCCGGTTTTCGATCAGCCCTGCTTGCCTTGCCTTTTATATGGACGGGGTGGGAGTGGG
CTTACATGCAGCAGGATTTTTCGCTCGGGTGGTTGACCTTCGGCAATTCGCAGGCCAATCTGCTCTGGATGGTACAGTAT
GCTGATGTGACGGGCGTGTGGGGCGTTAGTTTCTGGCTGTTGACTTTCAATGTGCTTGTGCTGTTGCTTTTCATGGAAAA
GGAGTCGTTTCAGGTGAAGGTGGGTATCGTAATGGTCATGCTTGTGATGATTGCTACTCCGCTTCTTTACGCGCGTCAGG
TTTTCCGGAATACGGCGTTGGATAATACTTCCCCTAAAGTACGTGTTGCGTTGGTGCAGCCTGATATCGATCCTCACGAA
AAATGGGATGGCCTCGGCCCGGAAGAGACCCTGTCACGGCTATACAGCCTGACCGGGCAATCGGTGCGCGGGGAGCGTCT
GGAGCTGATCATCTGGCCGGAAACCGCCATACCGTTTTATATCCGCTTGCCGGAAAACAAGCCCTACATGGACTCGGTCA
GGCGCATGGTCATGCGCTGGAATACCCCCTTGCTGACCGGATTTCCCGATGAGGTGCCGGTTTTTCCGAACTCTGCGAGG
GGCGAGGCTGTGGCTGCTTCCGGGGCGGAGTATGCCGCTTACAATGCCTCCATGCTTCTGCATCCGGCAGGCGGGCCGGT
GCAGATTTACCGGAAGATGCGCCTGGTGCCTTTCGGAGAGCGGGTTCCCTATTCGGAATATTTCCCCTGGCTGGAGAGGC
TCAGCTTTTCGATGTCAGGAATATCGAGCTGGGCGAAAGGGCGGGAAGCTACGGTCATGCACTTCACGAGCCGTGACGGT
CAGCCGGTCAGGATGGCCAACATTATCTGCTATGAATCGATTTTTCCCGGTCAGGTATCGACGTTTGTCAGGCGAGGTGC
GCAGTTCTTGACGCTTGTTACCAACGATGGCTGGTATGGTACATCGTATGGCCCGTGGCAACATGCGGCTATCGACAGGC
TCCGCTGCATCGAAAACCGCCGTGCTATGGCCCGCTGCGCCAATACTGGCGTGACCCTTTTCTACGATATCTGTGGGCGC
AGTTATGCTGAAACGCCCTGGTGGCAACAGTCGGTGCTGACTGCCGATGTGCCGCTTGAAAGCAGGATCACTTTTTACAC
GGCCCATCCGGATTTGGTGCCCCACGTATGTCTGGGGATTGCAGGTGTGCTGGCGCTGGTGGCGGCGGTGAGAAAGCGGT
AG

Upstream 100 bases:

>100_bases
GCTTCCGGCGACCTTCTTTCCGTTTCCTTTCAATAGTGTCTGCATTGACTCAGGCGAGCTGTTTCTGCCCATTATCATGT
CTTGTAAAGGGGTGTCAGTC

Downstream 100 bases:

>100_bases
TAGGCGAAAAACGAAAACGTGTTGTGAGCAACAATATGTAATTCTTCCTACAGTCCGTACTCCTTGATTTTGCGGTAGAG
CGTCCGCTCATTGATGCCGA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MNGAYRGALSRLLSKPFFLPLLSGLLLGISFPTWPAVHLEPLAWIALVPLLLSLEHEERFGPFFRKSWMSMLLFCLIALW
WVCLATFVGGILTVFVQSLFSVVPLVVFYYFKKRAGFRSALLALPFIWTGWEWAYMQQDFSLGWLTFGNSQANLLWMVQY
ADVTGVWGVSFWLLTFNVLVLLLFMEKESFQVKVGIVMVMLVMIATPLLYARQVFRNTALDNTSPKVRVALVQPDIDPHE
KWDGLGPEETLSRLYSLTGQSVRGERLELIIWPETAIPFYIRLPENKPYMDSVRRMVMRWNTPLLTGFPDEVPVFPNSAR
GEAVAASGAEYAAYNASMLLHPAGGPVQIYRKMRLVPFGERVPYSEYFPWLERLSFSMSGISSWAKGREATVMHFTSRDG
QPVRMANIICYESIFPGQVSTFVRRGAQFLTLVTNDGWYGTSYGPWQHAAIDRLRCIENRRAMARCANTGVTLFYDICGR
SYAETPWWQQSVLTADVPLESRITFYTAHPDLVPHVCLGIAGVLALVAAVRKR

Sequences:

>Translated_533_residues
MNGAYRGALSRLLSKPFFLPLLSGLLLGISFPTWPAVHLEPLAWIALVPLLLSLEHEERFGPFFRKSWMSMLLFCLIALW
WVCLATFVGGILTVFVQSLFSVVPLVVFYYFKKRAGFRSALLALPFIWTGWEWAYMQQDFSLGWLTFGNSQANLLWMVQY
ADVTGVWGVSFWLLTFNVLVLLLFMEKESFQVKVGIVMVMLVMIATPLLYARQVFRNTALDNTSPKVRVALVQPDIDPHE
KWDGLGPEETLSRLYSLTGQSVRGERLELIIWPETAIPFYIRLPENKPYMDSVRRMVMRWNTPLLTGFPDEVPVFPNSAR
GEAVAASGAEYAAYNASMLLHPAGGPVQIYRKMRLVPFGERVPYSEYFPWLERLSFSMSGISSWAKGREATVMHFTSRDG
QPVRMANIICYESIFPGQVSTFVRRGAQFLTLVTNDGWYGTSYGPWQHAAIDRLRCIENRRAMARCANTGVTLFYDICGR
SYAETPWWQQSVLTADVPLESRITFYTAHPDLVPHVCLGIAGVLALVAAVRKR
>Mature_533_residues
MNGAYRGALSRLLSKPFFLPLLSGLLLGISFPTWPAVHLEPLAWIALVPLLLSLEHEERFGPFFRKSWMSMLLFCLIALW
WVCLATFVGGILTVFVQSLFSVVPLVVFYYFKKRAGFRSALLALPFIWTGWEWAYMQQDFSLGWLTFGNSQANLLWMVQY
ADVTGVWGVSFWLLTFNVLVLLLFMEKESFQVKVGIVMVMLVMIATPLLYARQVFRNTALDNTSPKVRVALVQPDIDPHE
KWDGLGPEETLSRLYSLTGQSVRGERLELIIWPETAIPFYIRLPENKPYMDSVRRMVMRWNTPLLTGFPDEVPVFPNSAR
GEAVAASGAEYAAYNASMLLHPAGGPVQIYRKMRLVPFGERVPYSEYFPWLERLSFSMSGISSWAKGREATVMHFTSRDG
QPVRMANIICYESIFPGQVSTFVRRGAQFLTLVTNDGWYGTSYGPWQHAAIDRLRCIENRRAMARCANTGVTLFYDICGR
SYAETPWWQQSVLTADVPLESRITFYTAHPDLVPHVCLGIAGVLALVAAVRKR

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=397, Percent_Identity=27.9596977329975, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_CHLTE (Q8KCC4)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662383.1
- ProteinModelPortal:   Q8KCC4
- GeneID:   1006039
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1498
- NMPDR:   fig|194439.1.peg.1477
- TIGR:   CT1498
- HOGENOM:   HBG405346
- OMA:   IITNDGW
- ProtClustDB:   CLSK637794
- BioCyc:   CTEP194439:CT_1498-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 60528; Mature: 60528

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe34f6d8)-; HASH(0xe8972f4)-; HASH(0xd6fcf90)-; HASH(0xd8be874)-; HASH(0xebdb4f8)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGAYRGALSRLLSKPFFLPLLSGLLLGISFPTWPAVHLEPLAWIALVPLLLSLEHEERF
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHC
GPFFRKSWMSMLLFCLIALWWVCLATFVGGILTVFVQSLFSVVPLVVFYYFKKRAGFRSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLALPFIWTGWEWAYMQQDFSLGWLTFGNSQANLLWMVQYADVTGVWGVSFWLLTFNVLV
HHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LLLFMEKESFQVKVGIVMVMLVMIATPLLYARQVFRNTALDNTSPKVRVALVQPDIDPHE
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHH
KWDGLGPEETLSRLYSLTGQSVRGERLELIIWPETAIPFYIRLPENKPYMDSVRRMVMRW
HCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHC
NTPLLTGFPDEVPVFPNSARGEAVAASGAEYAAYNASMLLHPAGGPVQIYRKMRLVPFGE
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCEEEEECCCCHHHHHHHHHCCCCCC
RVPYSEYFPWLERLSFSMSGISSWAKGREATVMHFTSRDGQPVRMANIICYESIFPGQVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEHHHEEEHHCCCCHHHH
TFVRRGAQFLTLVTNDGWYGTSYGPWQHAAIDRLRCIENRRAMARCANTGVTLFYDICGR
HHHHCCCEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCC
SYAETPWWQQSVLTADVPLESRITFYTAHPDLVPHVCLGIAGVLALVAAVRKR
CCCCCCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNGAYRGALSRLLSKPFFLPLLSGLLLGISFPTWPAVHLEPLAWIALVPLLLSLEHEERF
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHC
GPFFRKSWMSMLLFCLIALWWVCLATFVGGILTVFVQSLFSVVPLVVFYYFKKRAGFRSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLALPFIWTGWEWAYMQQDFSLGWLTFGNSQANLLWMVQYADVTGVWGVSFWLLTFNVLV
HHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LLLFMEKESFQVKVGIVMVMLVMIATPLLYARQVFRNTALDNTSPKVRVALVQPDIDPHE
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHH
KWDGLGPEETLSRLYSLTGQSVRGERLELIIWPETAIPFYIRLPENKPYMDSVRRMVMRW
HCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHC
NTPLLTGFPDEVPVFPNSARGEAVAASGAEYAAYNASMLLHPAGGPVQIYRKMRLVPFGE
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCEEEEECCCCHHHHHHHHHCCCCCC
RVPYSEYFPWLERLSFSMSGISSWAKGREATVMHFTSRDGQPVRMANIICYESIFPGQVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEHHHEEEHHCCCCHHHH
TFVRRGAQFLTLVTNDGWYGTSYGPWQHAAIDRLRCIENRRAMARCANTGVTLFYDICGR
HHHHCCCEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCC
SYAETPWWQQSVLTADVPLESRITFYTAHPDLVPHVCLGIAGVLALVAAVRKR
CCCCCCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901