Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 21674186

GI number: 21674186

Start: 1282523

End: 1284007

Strand: Direct

Name: appC [H]

Synonym: CT1364

Alternate gene names: 21674186

Gene position: 1282523-1284007 (Clockwise)

Preceding gene: 21674184

Following gene: 21674187

Centisome position: 59.52

GC content: 59.73

Gene sequence:

>1485_bases
ATGGTTGCGCAACGAGCAAATAAGTCATCCATACCAGCCCTGTACCGCATCGTGCCGGGCCTTGGCCTTCTGAGCGCAGG
CAAACGCTCTTCGGGCCTCTTTTACCTGCTGGCGACGCTGGCGTTTTTCGCCCTGTTCGCGGCCAGACTCGACCTCGTCA
TCATCAGTTTGCGCTCGCTGGCCGCAGGCGTGACGCTTCTTGTTTTGTCGCCAACCAACTTCAGCCAGATATTCACCATT
GAAACCCTCGAATTCTGGATTGCCGCGCTCTACCTCATCATTGTTCCCTTCCTGCTCCTGCGCTTTTCCGTGCGTTCGTA
CCGCAAGGTGCTCAAGGAAAAAGATCAATCTCAATCCGGTGAAGCGAGCCTCTGGCAGCTCGGCATGATTTCGTTCAAGC
GCAATGGCATTTCGGTGGCGGCGTCGATGGTGATTTTCGTGCTCTACTCGGTCGCCTTCCTCGCGCCGCTGCTTTCGCCC
TTCAGCCCCTACGACCAGCAGGACTTCCTGGTCACCGCCTACCAGCCGCCGCTGACGCGCCTTGACGCGCTGGTGCTCCG
CCAGCACCAGACGATGGTCATGCCGCTTCGTCCCGGCAGCGACATGGCTTCCAAAGCAGCCAACACCCTGATTCTCGACA
GCCAGAAGCTCCGGTCGCGCAACGAGGAGCATAACCTGAAGTTCGTGAACAGCTACCGCATCGAAAGCAACGAGCTCCTC
TACCGGCAAGGCATGAGGGAAAAAAGCCTGCCGATCGATCAGCTCGTCAACGTTTCCGGAAGCAGCCAGAAGCCGGTTTA
CGCCGTCACGAAAACCTTCCTGCTCGGCACCGACCAGTACGGGCGCGACATCTTCAGCCGCGTCATCTATGGCTCGCGAA
TCTCGCTCTCCATCGGCTTTCTCGTCGTCCTCATCTCGGTCTCGCTCGGCACGGTCATCGGCATCTCGTCGGGCTACTTC
GGCGGCTGGGTGGACAACACGCTCATGCGCATCGTCGATGTGCTCATCGCCTTTCCGGCGCTCTTCCTGATTCTCATCAT
CATCGCCACCTTCGGCAACTCGATCTACCTGATCGTCATCACGCTCTCGTTCACCGGCTGGATGGGCGTGGCCCGAATCG
TGCGCGGACAGGTGCTCTCGCTCAAGGAGCAGGAGTTCATCCTGGCGGCCAAATCGCTCGGACTTTCCAACCTGCGCATC
ATCTTCCGCCATCTGTTGCCCAACACGCTGACGCCGGTAATCGTGGCCGCTACGCTCCGCATCGGCAGTATCATTCTGAC
CGAAGCGGGCCTCTCCTTCCTCGGCCTCGGCGTGCAACCGCCAACGCCAAGCTGGGGCAACATCATCAACGAAGGGCGCG
ACAGCTTGCTCAACCACTGGTGGATTTCAACCTTCCCCGGCGTGGCAATCCTGACCACCGTAGTCTGCTTCAACCTCATC
GGCGACGGCATCCGCGACGCCCTCGATCCGAGGATGCGCGGATGA

Upstream 100 bases:

>100_bases
GCGGCTTTTTTTACGGATTGCCGTTTGCAAATCGTGCAGCAAGTGTCGTTTTTTGGGTAACTTGAGGACATTTTGAGACT
GATTCATTCATCTATTCCCG

Downstream 100 bases:

>100_bases
GCAGACAAATCAACAACGATCCCGGACGCTGGGAGGTACTCGAATCGATCTACCTCCACCAGAGGCCGTGGCTCACCGTG
CGGCAGGATCGTGTGCGGCT

Product: peptide ABC transporter, permease protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MVAQRANKSSIPALYRIVPGLGLLSAGKRSSGLFYLLATLAFFALFAARLDLVIISLRSLAAGVTLLVLSPTNFSQIFTI
ETLEFWIAALYLIIVPFLLLRFSVRSYRKVLKEKDQSQSGEASLWQLGMISFKRNGISVAASMVIFVLYSVAFLAPLLSP
FSPYDQQDFLVTAYQPPLTRLDALVLRQHQTMVMPLRPGSDMASKAANTLILDSQKLRSRNEEHNLKFVNSYRIESNELL
YRQGMREKSLPIDQLVNVSGSSQKPVYAVTKTFLLGTDQYGRDIFSRVIYGSRISLSIGFLVVLISVSLGTVIGISSGYF
GGWVDNTLMRIVDVLIAFPALFLILIIIATFGNSIYLIVITLSFTGWMGVARIVRGQVLSLKEQEFILAAKSLGLSNLRI
IFRHLLPNTLTPVIVAATLRIGSIILTEAGLSFLGLGVQPPTPSWGNIINEGRDSLLNHWWISTFPGVAILTTVVCFNLI
GDGIRDALDPRMRG

Sequences:

>Translated_494_residues
MVAQRANKSSIPALYRIVPGLGLLSAGKRSSGLFYLLATLAFFALFAARLDLVIISLRSLAAGVTLLVLSPTNFSQIFTI
ETLEFWIAALYLIIVPFLLLRFSVRSYRKVLKEKDQSQSGEASLWQLGMISFKRNGISVAASMVIFVLYSVAFLAPLLSP
FSPYDQQDFLVTAYQPPLTRLDALVLRQHQTMVMPLRPGSDMASKAANTLILDSQKLRSRNEEHNLKFVNSYRIESNELL
YRQGMREKSLPIDQLVNVSGSSQKPVYAVTKTFLLGTDQYGRDIFSRVIYGSRISLSIGFLVVLISVSLGTVIGISSGYF
GGWVDNTLMRIVDVLIAFPALFLILIIIATFGNSIYLIVITLSFTGWMGVARIVRGQVLSLKEQEFILAAKSLGLSNLRI
IFRHLLPNTLTPVIVAATLRIGSIILTEAGLSFLGLGVQPPTPSWGNIINEGRDSLLNHWWISTFPGVAILTTVVCFNLI
GDGIRDALDPRMRG
>Mature_494_residues
MVAQRANKSSIPALYRIVPGLGLLSAGKRSSGLFYLLATLAFFALFAARLDLVIISLRSLAAGVTLLVLSPTNFSQIFTI
ETLEFWIAALYLIIVPFLLLRFSVRSYRKVLKEKDQSQSGEASLWQLGMISFKRNGISVAASMVIFVLYSVAFLAPLLSP
FSPYDQQDFLVTAYQPPLTRLDALVLRQHQTMVMPLRPGSDMASKAANTLILDSQKLRSRNEEHNLKFVNSYRIESNELL
YRQGMREKSLPIDQLVNVSGSSQKPVYAVTKTFLLGTDQYGRDIFSRVIYGSRISLSIGFLVVLISVSLGTVIGISSGYF
GGWVDNTLMRIVDVLIAFPALFLILIIIATFGNSIYLIVITLSFTGWMGVARIVRGQVLSLKEQEFILAAKSLGLSNLRI
IFRHLLPNTLTPVIVAATLRIGSIILTEAGLSFLGLGVQPPTPSWGNIINEGRDSLLNHWWISTFPGVAILTTVVCFNLI
GDGIRDALDPRMRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=220, Percent_Identity=46.3636363636364, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=43.37899543379, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787498, Length=218, Percent_Identity=46.7889908256881, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789964, Length=220, Percent_Identity=45.4545454545455, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1789889, Length=218, Percent_Identity=39.9082568807339, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=37.6146788990826, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787549, Length=221, Percent_Identity=33.4841628959276, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 54515; Mature: 54515

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQRANKSSIPALYRIVPGLGLLSAGKRSSGLFYLLATLAFFALFAARLDLVIISLRSL
CCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGVTLLVLSPTNFSQIFTIETLEFWIAALYLIIVPFLLLRFSVRSYRKVLKEKDQSQSG
HCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EASLWQLGMISFKRNGISVAASMVIFVLYSVAFLAPLLSPFSPYDQQDFLVTAYQPPLTR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHH
LDALVLRQHQTMVMPLRPGSDMASKAANTLILDSQKLRSRNEEHNLKFVNSYRIESNELL
HHHHHHHCCCCEEEEECCCCHHHHHHHCEEEECCHHHHCCCCCCCEEEEEEEECCCCHHH
YRQGMREKSLPIDQLVNVSGSSQKPVYAVTKTFLLGTDQYGRDIFSRVIYGSRISLSIGF
HHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
LVVLISVSLGTVIGISSGYFGGWVDNTLMRIVDVLIAFPALFLILIIIATFGNSIYLIVI
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
TLSFTGWMGVARIVRGQVLSLKEQEFILAAKSLGLSNLRIIFRHLLPNTLTPVIVAATLR
EECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
IGSIILTEAGLSFLGLGVQPPTPSWGNIINEGRDSLLNHWWISTFPGVAILTTVVCFNLI
HHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GDGIRDALDPRMRG
HHHHHHHCCCCCCC
>Mature Secondary Structure
MVAQRANKSSIPALYRIVPGLGLLSAGKRSSGLFYLLATLAFFALFAARLDLVIISLRSL
CCCCCCCCCCCHHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGVTLLVLSPTNFSQIFTIETLEFWIAALYLIIVPFLLLRFSVRSYRKVLKEKDQSQSG
HCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EASLWQLGMISFKRNGISVAASMVIFVLYSVAFLAPLLSPFSPYDQQDFLVTAYQPPLTR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHH
LDALVLRQHQTMVMPLRPGSDMASKAANTLILDSQKLRSRNEEHNLKFVNSYRIESNELL
HHHHHHHCCCCEEEEECCCCHHHHHHHCEEEECCHHHHCCCCCCCEEEEEEEECCCCHHH
YRQGMREKSLPIDQLVNVSGSSQKPVYAVTKTFLLGTDQYGRDIFSRVIYGSRISLSIGF
HHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
LVVLISVSLGTVIGISSGYFGGWVDNTLMRIVDVLIAFPALFLILIIIATFGNSIYLIVI
HHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
TLSFTGWMGVARIVRGQVLSLKEQEFILAAKSLGLSNLRIIFRHLLPNTLTPVIVAATLR
EECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHH
IGSIILTEAGLSFLGLGVQPPTPSWGNIINEGRDSLLNHWWISTFPGVAILTTVVCFNLI
HHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GDGIRDALDPRMRG
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]