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The map label for this gene is nudF [H]

Identifier: 21674187

GI number: 21674187

Start: 1284004

End: 1284591

Strand: Direct

Name: nudF [H]

Synonym: CT1365

Alternate gene names: 21674187

Gene position: 1284004-1284591 (Clockwise)

Preceding gene: 21674186

Following gene: 21674188

Centisome position: 59.58

GC content: 59.52

Gene sequence:

>588_bases
ATGAGCAGACAAATCAACAACGATCCCGGACGCTGGGAGGTACTCGAATCGATCTACCTCCACCAGAGGCCGTGGCTCAC
CGTGCGGCAGGATCGTGTGCGGCTTTCAAGCGGCAAAACGATAGACGACTACTACGTACAGGAATTTCCCCATTGGGTGA
ACGTGCTGGCCATCACGGAGGAACGTGACGTCGTGCTGATCCGCCAGTACCGCCACGGCATCGGCGAGGTGTCATGGGAG
CTGCCTGCCGGAGTGCTCGATGAAGGAGAATCGCTGCTCGACGGAGCGCAACGGGAGCTGCTCGAAGAGACCGGCTACAG
CGGCGGAACGTGGACGCCCCTGATGGAGCTGAGTGCAAATCCGGCGCTTCAGAACAACATCTCCTACTCGTTCCTCGCTG
AGGGCGTGAGCCTGTCCGGCACGCAGCACCTCGACCCGACCGAAGAGATCACCGTGCACCTGATGCCGCTCGACCGTCTG
CGCGAAATCGTGTTTGACGGCGGAATGATTCAGGCCCTGCACGCAGCTCCGATACTCAAGTACCTATTGCAAAACAGGTG
GGGGGAATCGGTAAAAGGAGAGGGATAG

Upstream 100 bases:

>100_bases
GGATTTCAACCTTCCCCGGCGTGGCAATCCTGACCACCGTAGTCTGCTTCAACCTCATCGGCGACGGCATCCGCGACGCC
CTCGATCCGAGGATGCGCGG

Downstream 100 bases:

>100_bases
CATGAAAAAACAGCAGCAGCTCGATCTGCTCGAAAAGGCGCTGGTCTCGACCGGACACAAAATCAGATATGAAAAGGGCA
GTTTCGTCGGAGGCGACTGC

Product: Nudix/MutT family protein, putative

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSRQINNDPGRWEVLESIYLHQRPWLTVRQDRVRLSSGKTIDDYYVQEFPHWVNVLAITEERDVVLIRQYRHGIGEVSWE
LPAGVLDEGESLLDGAQRELLEETGYSGGTWTPLMELSANPALQNNISYSFLAEGVSLSGTQHLDPTEEITVHLMPLDRL
REIVFDGGMIQALHAAPILKYLLQNRWGESVKGEG

Sequences:

>Translated_195_residues
MSRQINNDPGRWEVLESIYLHQRPWLTVRQDRVRLSSGKTIDDYYVQEFPHWVNVLAITEERDVVLIRQYRHGIGEVSWE
LPAGVLDEGESLLDGAQRELLEETGYSGGTWTPLMELSANPALQNNISYSFLAEGVSLSGTQHLDPTEEITVHLMPLDRL
REIVFDGGMIQALHAAPILKYLLQNRWGESVKGEG
>Mature_194_residues
SRQINNDPGRWEVLESIYLHQRPWLTVRQDRVRLSSGKTIDDYYVQEFPHWVNVLAITEERDVVLIRQYRHGIGEVSWEL
PAGVLDEGESLLDGAQRELLEETGYSGGTWTPLMELSANPALQNNISYSFLAEGVSLSGTQHLDPTEEITVHLMPLDRLR
EIVFDGGMIQALHAAPILKYLLQNRWGESVKGEG

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 22153; Mature: 22022

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQINNDPGRWEVLESIYLHQRPWLTVRQDRVRLSSGKTIDDYYVQEFPHWVNVLAITE
CCCCCCCCCCHHHHHHHHHHCCCCCEEEHHCEEECCCCCCHHHHHHHHCCCCEEEEEEEC
ERDVVLIRQYRHGIGEVSWELPAGVLDEGESLLDGAQRELLEETGYSGGTWTPLMELSAN
CCCEEEHHHHHCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCC
PALQNNISYSFLAEGVSLSGTQHLDPTEEITVHLMPLDRLREIVFDGGMIQALHAAPILK
CCHHCCCCHHHHHCCCCCCCCCCCCCCHHEEEEEECHHHHHHHHHCCCHHHHHHHHHHHH
YLLQNRWGESVKGEG
HHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRQINNDPGRWEVLESIYLHQRPWLTVRQDRVRLSSGKTIDDYYVQEFPHWVNVLAITE
CCCCCCCCCHHHHHHHHHHCCCCCEEEHHCEEECCCCCCHHHHHHHHCCCCEEEEEEEC
ERDVVLIRQYRHGIGEVSWELPAGVLDEGESLLDGAQRELLEETGYSGGTWTPLMELSAN
CCCEEEHHHHHCCCCCEEECCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCC
PALQNNISYSFLAEGVSLSGTQHLDPTEEITVHLMPLDRLREIVFDGGMIQALHAAPILK
CCHHCCCCHHHHHCCCCCCCCCCCCCCHHEEEEEECHHHHHHHHHCCCHHHHHHHHHHHH
YLLQNRWGESVKGEG
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]