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The map label for this gene is nrnA [H]

Identifier: 21674007

GI number: 21674007

Start: 1110838

End: 1111899

Strand: Reverse

Name: nrnA [H]

Synonym: CT1181

Alternate gene names: 21674007

Gene position: 1111899-1110838 (Counterclockwise)

Preceding gene: 21674008

Following gene: 21674006

Centisome position: 51.6

GC content: 52.73

Gene sequence:

>1062_bases
ATGATTATACCCGAATATGGCCGGACATTGACCCCTGAAGAGTGGAGGCCGGTCGTCGATGAGATGCTGGAAGCCACGCA
CATTATTTTTACCACCCACGAAAATTCAGATGGCGACGGGCTTGGCAGCCAGGTCGCCCTTGCTCTCGCACTCAAGGCTC
TGGGCAAGGAGGTTGCGATTTTCAATCCAACGGAAGTGCCGCCGAACTATCTGTTCCTGAAGGAACTTCATGAGATTAAC
CTTTTTCGTGACCGGGACGAGGAGTCCATGCAGGAGTTTTTTCTTGCTGATCTTCTGGTTGTGCTCGATGCCAATCTGCA
CGACCGTATTGGCAGACTTTGGCCGCATGTGGAGTTTGCCAGGCAGATGAGCCGACTCAAAGTGCTCTGCATTGATCATC
ATCTCGAACCGGAGGATTTTGCCGATATCACAGTGTGCGAAACCTACGCATCTTCGACCGGTGAGCTTGTCTGTGATCTT
GTTACCGCCCTGGAGCTGCGTACCGGGCAGCAGCTGTTTACTCCCGAAGTGGCTTCAGCTCTCTATGCAGCTATCATGAC
CGATACTGGCTCGTTCAGGTTCCCCAAGACGACACCCTACACCTATCGACTTGCCGGAATGCTGGTCGAAAAAGGGGCCG
ATCCTGAGCTGGTGTACGACCGCATCTACAACGCCTTGACGCCGGAGGCGCTCAAGCTGCTTGGCCTTTCGCTTTCAAAT
ATCAAGATCATTGAGAACGGTCTGATTTCCTGGCTTTTCATCACTCAGGAAATGCTCGAACAGACGGGCAGCAAGCTGTT
CGACACCGATCTTATTATTCGCTATCTTTTGAGCGTGCCTACAGTGAAGGTTGCCGTTCTCCTTGTAGAGATGCAGGATG
GACGGTGTAAGGTCAGCTTCAGGTCGCGGGGCAAGATTTATGTCAACCAGTTGGCCAAACACTATGGCGGCGGTGGTCAC
ATGAACGCTGCCGGCTGCCTGTTGAGAATGTCGGCAGAGAAGGCGCAACTTGTGATTCTTGAGGATGTCCGGAAGTTCAC
CCTCGAACAGGTGGACAGTTAA

Upstream 100 bases:

>100_bases
TTCTGCTGATGTCCTGAAATTATCGGATTCCGTCCGTCCGATTATTTCTGTATTATATGCTCGTTTCCGTTGAGTATTTC
GCAAACTATTTCCAGCGCTG

Downstream 100 bases:

>100_bases
TTTCTTTCAATTATTTCCCATTTACGTGCAAGCATGAAATGTACTGTTACGGCTAAAGAGAGCGGCCTGGTTAATGCCGA
TATTCTCGTCCAGTTTTTCA

Product: DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MIIPEYGRTLTPEEWRPVVDEMLEATHIIFTTHENSDGDGLGSQVALALALKALGKEVAIFNPTEVPPNYLFLKELHEIN
LFRDRDEESMQEFFLADLLVVLDANLHDRIGRLWPHVEFARQMSRLKVLCIDHHLEPEDFADITVCETYASSTGELVCDL
VTALELRTGQQLFTPEVASALYAAIMTDTGSFRFPKTTPYTYRLAGMLVEKGADPELVYDRIYNALTPEALKLLGLSLSN
IKIIENGLISWLFITQEMLEQTGSKLFDTDLIIRYLLSVPTVKVAVLLVEMQDGRCKVSFRSRGKIYVNQLAKHYGGGGH
MNAAGCLLRMSAEKAQLVILEDVRKFTLEQVDS

Sequences:

>Translated_353_residues
MIIPEYGRTLTPEEWRPVVDEMLEATHIIFTTHENSDGDGLGSQVALALALKALGKEVAIFNPTEVPPNYLFLKELHEIN
LFRDRDEESMQEFFLADLLVVLDANLHDRIGRLWPHVEFARQMSRLKVLCIDHHLEPEDFADITVCETYASSTGELVCDL
VTALELRTGQQLFTPEVASALYAAIMTDTGSFRFPKTTPYTYRLAGMLVEKGADPELVYDRIYNALTPEALKLLGLSLSN
IKIIENGLISWLFITQEMLEQTGSKLFDTDLIIRYLLSVPTVKVAVLLVEMQDGRCKVSFRSRGKIYVNQLAKHYGGGGH
MNAAGCLLRMSAEKAQLVILEDVRKFTLEQVDS
>Mature_353_residues
MIIPEYGRTLTPEEWRPVVDEMLEATHIIFTTHENSDGDGLGSQVALALALKALGKEVAIFNPTEVPPNYLFLKELHEIN
LFRDRDEESMQEFFLADLLVVLDANLHDRIGRLWPHVEFARQMSRLKVLCIDHHLEPEDFADITVCETYASSTGELVCDL
VTALELRTGQQLFTPEVASALYAAIMTDTGSFRFPKTTPYTYRLAGMLVEKGADPELVYDRIYNALTPEALKLLGLSLSN
IKIIENGLISWLFITQEMLEQTGSKLFDTDLIIRYLLSVPTVKVAVLLVEMQDGRCKVSFRSRGKIYVNQLAKHYGGGGH
MNAAGCLLRMSAEKAQLVILEDVRKFTLEQVDS

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 39712; Mature: 39712

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPEYGRTLTPEEWRPVVDEMLEATHIIFTTHENSDGDGLGSQVALALALKALGKEVAI
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEE
FNPTEVPPNYLFLKELHEINLFRDRDEESMQEFFLADLLVVLDANLHDRIGRLWPHVEFA
ECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
RQMSRLKVLCIDHHLEPEDFADITVCETYASSTGELVCDLVTALELRTGQQLFTPEVASA
HHHHHHEEEEEECCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCHHCCHHHHHH
LYAAIMTDTGSFRFPKTTPYTYRLAGMLVEKGADPELVYDRIYNALTPEALKLLGLSLSN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCC
IKIIENGLISWLFITQEMLEQTGSKLFDTDLIIRYLLSVPTVKVAVLLVEMQDGRCKVSF
EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEEEEEEEECCCEEEEEE
RSRGKIYVNQLAKHYGGGGHMNAAGCLLRMSAEKAQLVILEDVRKFTLEQVDS
CCCCCHHHHHHHHHCCCCCCCCHHHHHEEECCCCHHEEHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIPEYGRTLTPEEWRPVVDEMLEATHIIFTTHENSDGDGLGSQVALALALKALGKEVAI
CCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEE
FNPTEVPPNYLFLKELHEINLFRDRDEESMQEFFLADLLVVLDANLHDRIGRLWPHVEFA
ECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
RQMSRLKVLCIDHHLEPEDFADITVCETYASSTGELVCDLVTALELRTGQQLFTPEVASA
HHHHHHEEEEEECCCCCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCHHCCHHHHHH
LYAAIMTDTGSFRFPKTTPYTYRLAGMLVEKGADPELVYDRIYNALTPEALKLLGLSLSN
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHCCCCCC
IKIIENGLISWLFITQEMLEQTGSKLFDTDLIIRYLLSVPTVKVAVLLVEMQDGRCKVSF
EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEEEEEEEECCCEEEEEE
RSRGKIYVNQLAKHYGGGGHMNAAGCLLRMSAEKAQLVILEDVRKFTLEQVDS
CCCCCHHHHHHHHHCCCCCCCCHHHHHEEECCCCHHEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]