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The map label for this gene is btuR [H]

Identifier: 21673769

GI number: 21673769

Start: 889688

End: 890212

Strand: Direct

Name: btuR [H]

Synonym: CT0941

Alternate gene names: 21673769

Gene position: 889688-890212 (Clockwise)

Preceding gene: 21673768

Following gene: 21673770

Centisome position: 41.29

GC content: 58.67

Gene sequence:

>525_bases
ATGTCACAAAAACGGGTTCTTCTTTTCACAGGTAACGGCAAGGGCAAAAGCACGGCCGCGTTCGGAATGCTGTCGCGTGC
GCTCGGCCACGGTCTGAAAGTGCGTGTCATCCAGTTCGTCAAGGCCCAGGAGGGGGTTGGGGAGGTGCTTTTCTTTACGC
GCTTCGAGGATGTCGAGTGGGATCACTACGGCAAGGGATTCCTGCCGACCAATCCCGACAGCCCGATGATGGAGAAGCAC
AAACAGGCGGCGGAGTTCGGCTTCGAGGAGGCGCTCGACGCGCTGGCTTCGGACGAGTACGATTTCGTGCTGCTCGACGA
GGTGTGTTTCGCGCTCTCGAAAGAAATCATTCCGCTCGAGCCGCTCATCAAGGCGATTGTCGATGCCAGTGACAAGATCA
TCGTGCTGACCGGCCGCAATGCGCCGCAGGCGTTGATCGACGTGGCCGACACCGTGACAGAGATGAAGATGATCAAGCAC
GGCTACGAGCAGGGATTGCTCTCACAGGCTGGCGTGGAGGAGTGA

Upstream 100 bases:

>100_bases
AGGCGCCATGCGCCTGATGTACGTTGCCTCGGTTCTGTTCATGGCCTGTGGCGCGCTGCTGCTTTTTATTCTTTCCAAGT
CTCTACAATCGTAATCAGTT

Downstream 100 bases:

>100_bases
GCCTGACGCGCTTACATAAAACGAATGGCGGTGACGGCTGCCGCCCGATGATCGTCAAAGGTTCGCCGGTCAATCGCCGA
CGGGCGCTGTTGCTGGCGGC

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSQKRVLLFTGNGKGKSTAAFGMLSRALGHGLKVRVIQFVKAQEGVGEVLFFTRFEDVEWDHYGKGFLPTNPDSPMMEKH
KQAAEFGFEEALDALASDEYDFVLLDEVCFALSKEIIPLEPLIKAIVDASDKIIVLTGRNAPQALIDVADTVTEMKMIKH
GYEQGLLSQAGVEE

Sequences:

>Translated_174_residues
MSQKRVLLFTGNGKGKSTAAFGMLSRALGHGLKVRVIQFVKAQEGVGEVLFFTRFEDVEWDHYGKGFLPTNPDSPMMEKH
KQAAEFGFEEALDALASDEYDFVLLDEVCFALSKEIIPLEPLIKAIVDASDKIIVLTGRNAPQALIDVADTVTEMKMIKH
GYEQGLLSQAGVEE
>Mature_173_residues
SQKRVLLFTGNGKGKSTAAFGMLSRALGHGLKVRVIQFVKAQEGVGEVLFFTRFEDVEWDHYGKGFLPTNPDSPMMEKHK
QAAEFGFEEALDALASDEYDFVLLDEVCFALSKEIIPLEPLIKAIVDASDKIIVLTGRNAPQALIDVADTVTEMKMIKHG
YEQGLLSQAGVEE

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=169, Percent_Identity=34.9112426035503, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19193; Mature: 19062

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKRVLLFTGNGKGKSTAAFGMLSRALGHGLKVRVIQFVKAQEGVGEVLFFTRFEDVEW
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
DHYGKGFLPTNPDSPMMEKHKQAAEFGFEEALDALASDEYDFVLLDEVCFALSKEIIPLE
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHH
PLIKAIVDASDKIIVLTGRNAPQALIDVADTVTEMKMIKHGYEQGLLSQAGVEE
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQKRVLLFTGNGKGKSTAAFGMLSRALGHGLKVRVIQFVKAQEGVGEVLFFTRFEDVEW
CCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCC
DHYGKGFLPTNPDSPMMEKHKQAAEFGFEEALDALASDEYDFVLLDEVCFALSKEIIPLE
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHH
PLIKAIVDASDKIIVLTGRNAPQALIDVADTVTEMKMIKHGYEQGLLSQAGVEE
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]