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The map label for this gene is hdrA-1 [H]

Identifier: 21673695

GI number: 21673695

Start: 823221

End: 824462

Strand: Direct

Name: hdrA-1 [H]

Synonym: CT0866

Alternate gene names: 21673695

Gene position: 823221-824462 (Clockwise)

Preceding gene: 21673694

Following gene: 21673696

Centisome position: 38.2

GC content: 55.23

Gene sequence:

>1242_bases
ATGTCAGTTGAAACCATTTTAGTTGTCGGTGGCGGTATCAGCGGAATAACCACGGCGGTCGAGGCTGCCGAGGTCGGTTA
CAACACTGTGCTTGTCGAGAAGAAACCCTACCTTGGTGGCAGGGCCGCGCAGCTCAACAAGTATTTCCCGAAACTGTGCC
CCCCGTATTGCGGCCTGGAGATGAACTTCAGACGCATCAAGCCCAATCCGAAAATCACCGTCTACACCATGACTGAAGTC
GAGTCGGTGAGCGGTCAGGAAGGAAATTACAGCGTCAGGCTCAAGGTCAGCCCGCGCTTCGTGAATGAAAAGTGCACGGC
CTGCAACGCCTGCGCCGAGGCATGCCCTGTGGAGAGGCCAAACGAATTCAATTTCGGGATGGATAAGACAAAAGCGGCCT
ATCTCCCGCATGTGCTGTCCTATCCCATGAGATATGTTATAGACAGAGACGCTTGCAAGGATAACTCCTGCGACAAGTGC
GTCAAGGCGTGCAAATACAACGCCATCGATCTCAATATGAAACCGCAGACCATCGAGATGAAGGTCGGCAGCATCGTCTA
TGCCACAGGCTGGAATCCCTACGATGCGACCCGGATGGACAATCTCGGTTTCGGACGAGTCAAAAATGTCATCACCAACA
TGATGATGGAGCGTCTCGCTGCGCCGAACGGCCCGACGGGCGGAAAACTCCTGAGGCCTTCGGATAACAAGGAGGTCAAG
AAAGTGGTCTTCGTGCAGTGTGCCGGATCGAGGGACGAGAATCACCTCAATTACTGCTCGTCGATCTGCTGCATGGCCTC
GCTTAAGCAGGCTACCTATGTTCGGGAACGCATTCCGGATTCACAGGTTGTCGTGGCCTACATCGATCTGCGCGCGCCCG
GCAAGTATGAGGAGTTCCTCAACAAGGTCGAGGCTGACGCGAACGTGAAGCTGGTCAAGGGCAAAGTCGCCAAGATCGAG
GAAGACAAAGCCACCGGCGGTGTCATTCTCGAATTTGAGGATGTCGAGGGCGGCGGCAAAAGGCATGAACATGCCGACAT
GGCCGTGCTCGCCACTGGTATGGAGCCGTGCGTCAAGGCGAACTCAATGCTGAGTTTCGAGGAGAACGGCTTCATCAATG
GTGGCTCTGCCGCCGGAATCTACTCGACCGGTGTCGCCAAGAGGCCGTCCGATGTGACCACCGCCATCCAGGATGCGACC
GGCATGGCATTGAAAAGCATTCAAAGTCTCGTGAGGAGTTAA

Upstream 100 bases:

>100_bases
GGATTGCTTTATTGGCACCCGGATTTTGTAAGTTGAATACTGCTTTGTGTCCTGTTTTCAGGAGTGTTGATTTTTGAGAG
TTTATCCGCAGAGGAAAATC

Downstream 100 bases:

>100_bases
ACTATGGCTGATGACAAAAAAATAGGCGTATACCTCTGTACCGACTGCGGAATCGGGGAGGCGTTGAATGTGGATGAACT
TGAAGCGGTAGCCAAAAAGG

Product: heterodisulfide reductase, subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSVETILVVGGGISGITTAVEAAEVGYNTVLVEKKPYLGGRAAQLNKYFPKLCPPYCGLEMNFRRIKPNPKITVYTMTEV
ESVSGQEGNYSVRLKVSPRFVNEKCTACNACAEACPVERPNEFNFGMDKTKAAYLPHVLSYPMRYVIDRDACKDNSCDKC
VKACKYNAIDLNMKPQTIEMKVGSIVYATGWNPYDATRMDNLGFGRVKNVITNMMMERLAAPNGPTGGKLLRPSDNKEVK
KVVFVQCAGSRDENHLNYCSSICCMASLKQATYVRERIPDSQVVVAYIDLRAPGKYEEFLNKVEADANVKLVKGKVAKIE
EDKATGGVILEFEDVEGGGKRHEHADMAVLATGMEPCVKANSMLSFEENGFINGGSAAGIYSTGVAKRPSDVTTAIQDAT
GMALKSIQSLVRS

Sequences:

>Translated_413_residues
MSVETILVVGGGISGITTAVEAAEVGYNTVLVEKKPYLGGRAAQLNKYFPKLCPPYCGLEMNFRRIKPNPKITVYTMTEV
ESVSGQEGNYSVRLKVSPRFVNEKCTACNACAEACPVERPNEFNFGMDKTKAAYLPHVLSYPMRYVIDRDACKDNSCDKC
VKACKYNAIDLNMKPQTIEMKVGSIVYATGWNPYDATRMDNLGFGRVKNVITNMMMERLAAPNGPTGGKLLRPSDNKEVK
KVVFVQCAGSRDENHLNYCSSICCMASLKQATYVRERIPDSQVVVAYIDLRAPGKYEEFLNKVEADANVKLVKGKVAKIE
EDKATGGVILEFEDVEGGGKRHEHADMAVLATGMEPCVKANSMLSFEENGFINGGSAAGIYSTGVAKRPSDVTTAIQDAT
GMALKSIQSLVRS
>Mature_412_residues
SVETILVVGGGISGITTAVEAAEVGYNTVLVEKKPYLGGRAAQLNKYFPKLCPPYCGLEMNFRRIKPNPKITVYTMTEVE
SVSGQEGNYSVRLKVSPRFVNEKCTACNACAEACPVERPNEFNFGMDKTKAAYLPHVLSYPMRYVIDRDACKDNSCDKCV
KACKYNAIDLNMKPQTIEMKVGSIVYATGWNPYDATRMDNLGFGRVKNVITNMMMERLAAPNGPTGGKLLRPSDNKEVKK
VVFVQCAGSRDENHLNYCSSICCMASLKQATYVRERIPDSQVVVAYIDLRAPGKYEEFLNKVEADANVKLVKGKVAKIEE
DKATGGVILEFEDVEGGGKRHEHADMAVLATGMEPCVKANSMLSFEENGFINGGSAAGIYSTGVAKRPSDVTTAIQDATG
MALKSIQSLVRS

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 45095; Mature: 44964

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVETILVVGGGISGITTAVEAAEVGYNTVLVEKKPYLGGRAAQLNKYFPKLCPPYCGLE
CCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCC
MNFRRIKPNPKITVYTMTEVESVSGQEGNYSVRLKVSPRFVNEKCTACNACAEACPVERP
CCEEEECCCCCEEEEEEEEEHHCCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHCCCCCC
NEFNFGMDKTKAAYLPHVLSYPMRYVIDRDACKDNSCDKCVKACKYNAIDLNMKPQTIEM
CCCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCEEEE
KVGSIVYATGWNPYDATRMDNLGFGRVKNVITNMMMERLAAPNGPTGGKLLRPSDNKEVK
EECEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEE
KVVFVQCAGSRDENHLNYCSSICCMASLKQATYVRERIPDSQVVVAYIDLRAPGKYEEFL
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
NKVEADANVKLVKGKVAKIEEDKATGGVILEFEDVEGGGKRHEHADMAVLATGMEPCVKA
HHHCCCCCEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHHHCC
NSMLSFEENGFINGGSAAGIYSTGVAKRPSDVTTAIQDATGMALKSIQSLVRS
CCEEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVETILVVGGGISGITTAVEAAEVGYNTVLVEKKPYLGGRAAQLNKYFPKLCPPYCGLE
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCC
MNFRRIKPNPKITVYTMTEVESVSGQEGNYSVRLKVSPRFVNEKCTACNACAEACPVERP
CCEEEECCCCCEEEEEEEEEHHCCCCCCCEEEEEEECCHHHCCHHHHHHHHHHHCCCCCC
NEFNFGMDKTKAAYLPHVLSYPMRYVIDRDACKDNSCDKCVKACKYNAIDLNMKPQTIEM
CCCCCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCEEEE
KVGSIVYATGWNPYDATRMDNLGFGRVKNVITNMMMERLAAPNGPTGGKLLRPSDNKEVK
EECEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEE
KVVFVQCAGSRDENHLNYCSSICCMASLKQATYVRERIPDSQVVVAYIDLRAPGKYEEFL
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHH
NKVEADANVKLVKGKVAKIEEDKATGGVILEFEDVEGGGKRHEHADMAVLATGMEPCVKA
HHHCCCCCEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCHHHHCC
NSMLSFEENGFINGGSAAGIYSTGVAKRPSDVTTAIQDATGMALKSIQSLVRS
CCEEEECCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]