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The map label for this gene is ndhH [H]

Identifier: 21673597

GI number: 21673597

Start: 739812

End: 740381

Strand: Direct

Name: ndhH [H]

Synonym: CT0767

Alternate gene names: 21673597

Gene position: 739812-740381 (Clockwise)

Preceding gene: 21673596

Following gene: 21673598

Centisome position: 34.33

GC content: 56.84

Gene sequence:

>570_bases
ATGGGTTTGCTTGACGCCAGAATATCGAACCGCAACGTGCTGGTGACTTCGGTTGACAACGTGATGAACTGGGCTCGCCT
CTCCTCCCTTTGGCCGATGGGTTTTGGTCTGGCCTGCTGCGCTATTGAGATGATGGCCACCAACGCTTCGAACTACGATC
TCGAACGTTTCGGTATTTTTCCTCGTTCGTCGCCCCGCCAGTCTGACCTCATGATCGTGGCCGGAACGGTCACCATGAAG
ATGGCCGAGAGGGTGGTGACGCTTTACGAACAGATGCCCGAACCGCGCTATGTGCTGTCGATGGGAAGCTGCTCGAACAG
TGGCGGACCCTACTGGCATCATGGTTACCATGTGCTCAAAGGTGTTGATCGTATCATTCCGGTCGATGTGTACGTTCCCG
GCTGTCCTCCGCGCCCCGAGGCGCTGATCGGCGGCCTGATGAAAATCCAGGAGCTGATCCGGATGGAGGGACTTGGCATT
TCTCGCCAGGATGCCCTGAAGAAGCTTGCAGGAAAGCGTGTTGATCCGCAGCAGGTGATCGACCAGGTTCGCAAGTCGGC
TACGGCATAA

Upstream 100 bases:

>100_bases
GGTTCGCCCGACTCCAAATATCCCGAAAATGCCGGAGATGCCTGTTCGTCGCTCCGGCAAGGCGAACGGATAATCTTTCA
ATCATCATCGATTTTACGCT

Downstream 100 bases:

>100_bases
CCACTATTATCTATCAAGAATTCAAGGGAATGGAAGAAGCAGCAAACCAGATGTCGCCAGCGGTGCAGCAGAGCAAAGCC
GCTTATGATAATATAAAGGA

Product: NADH dehydrogenase subunit B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MGLLDARISNRNVLVTSVDNVMNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIFPRSSPRQSDLMIVAGTVTMK
MAERVVTLYEQMPEPRYVLSMGSCSNSGGPYWHHGYHVLKGVDRIIPVDVYVPGCPPRPEALIGGLMKIQELIRMEGLGI
SRQDALKKLAGKRVDPQQVIDQVRKSATA

Sequences:

>Translated_189_residues
MGLLDARISNRNVLVTSVDNVMNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIFPRSSPRQSDLMIVAGTVTMK
MAERVVTLYEQMPEPRYVLSMGSCSNSGGPYWHHGYHVLKGVDRIIPVDVYVPGCPPRPEALIGGLMKIQELIRMEGLGI
SRQDALKKLAGKRVDPQQVIDQVRKSATA
>Mature_188_residues
GLLDARISNRNVLVTSVDNVMNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIFPRSSPRQSDLMIVAGTVTMKM
AERVVTLYEQMPEPRYVLSMGSCSNSGGPYWHHGYHVLKGVDRIIPVDVYVPGCPPRPEALIGGLMKIQELIRMEGLGIS
RQDALKKLAGKRVDPQQVIDQVRKSATA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=148, Percent_Identity=58.7837837837838, Blast_Score=196, Evalue=9e-51,
Organism=Escherichia coli, GI1788624, Length=148, Percent_Identity=52.027027027027, Blast_Score=164, Evalue=2e-42,
Organism=Escherichia coli, GI1789074, Length=148, Percent_Identity=38.5135135135135, Blast_Score=103, Evalue=6e-24,
Organism=Escherichia coli, GI1788834, Length=129, Percent_Identity=37.2093023255814, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17509685, Length=146, Percent_Identity=53.4246575342466, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI18859983, Length=142, Percent_Identity=56.3380281690141, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24642371, Length=142, Percent_Identity=56.3380281690141, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24651058, Length=137, Percent_Identity=56.2043795620438, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20926; Mature: 20795

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS01150 COMPLEX1_20K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLDARISNRNVLVTSVDNVMNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIF
CCCCCCEECCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
PRSSPRQSDLMIVAGTVTMKMAERVVTLYEQMPEPRYVLSMGSCSNSGGPYWHHGYHVLK
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
GVDRIIPVDVYVPGCPPRPEALIGGLMKIQELIRMEGLGISRQDALKKLAGKRVDPQQVI
HHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
DQVRKSATA
HHHHHHCCC
>Mature Secondary Structure 
GLLDARISNRNVLVTSVDNVMNWARLSSLWPMGFGLACCAIEMMATNASNYDLERFGIF
CCCCCEECCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCC
PRSSPRQSDLMIVAGTVTMKMAERVVTLYEQMPEPRYVLSMGSCSNSGGPYWHHGYHVLK
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
GVDRIIPVDVYVPGCPPRPEALIGGLMKIQELIRMEGLGISRQDALKKLAGKRVDPQQVI
HHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
DQVRKSATA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA