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The map label for this gene is era [H]

Identifier: 21673128

GI number: 21673128

Start: 300491

End: 301408

Strand: Reverse

Name: era [H]

Synonym: CT0289

Alternate gene names: 21673128

Gene position: 301408-300491 (Counterclockwise)

Preceding gene: 21673130

Following gene: 21673124

Centisome position: 13.99

GC content: 55.12

Gene sequence:

>918_bases
GTGCAGCCACCACTATTTTCTTGCGGCCACGTAACCTTTGTCGGCGCGCCAAATGCGGGCAAATCGACCCTACTGAACCG
TCTGCTGGATCACAAGCTATCGATTGTCACCCCAAAACCGCAAACGACAAGAAAAAAAATTACCGGAATTTACCATGACG
ACCGGAGCCAGATCATTATTCTCGACACTCCCGGCATCATGGACCCAAAGCAATCGCTGCACGAATCGATGCTCGAAATC
ACCCGGCGCTCGCTCCGGGAGTCAGATGTCATTGTCGCGCTCATCCCGTTCCAGAAAGGCGACGAACCCATCGACCGGAA
ATTCGCCAGCGAACTGATCGAACAGTGGGTGAAGCCTACAGGCAAACCCTTCGTCATCGCACTGAACAAAGCCGACCTCG
TGCCGGAAGAGACCGCCAAAGAGGCGCAAACGGAGATCATAAGCAAGTACAAGCCCGTGGCGACGCTCGCCCTGTCAGCC
CTCACCGGCGGCAACATACCAGAGCTGGTCGAGCTGCTCAGGCCACTGTTACCATTCGACGAACCGATCTGGCCGGATGA
CATTCTCAGCACCGAGCCGGAGCGCTTTTTCGTCGGCGAGATCATCCGCGAAAAAATCTTTCTGCAATACGGGCGCGAAA
TTCCCTACTCAACCGAGGTAGTCATCGATGAATTCAAGGAGCAGCACGAAAACAACCCAAGCCGCAAGGAGCTGATCCGC
TGCTCGGTCATTGTCGAACGCAACAGCCAGAAGCAGATCATCGTCGGCCAGAAGGGCGCGGCCATCAAAAAACTCGGCCA
GGCCGCTCGCAAGGAAATAGAAGAACTCCTTGACCGACCGGTGTACCTCGAAATTTTCGTGAAGGTCCGCCCCGACTGGC
GCAAAAAAAAGAACCTCCTCAAAAGCTACGGCTACTGA

Upstream 100 bases:

>100_bases
AGAGATCATGTTATCTTGCCGGGAAACAGCTCCATAAACCACCGGAACAGGTTTTCCACACGTATCCCGGCACCCAAATC
ATACAAGAGAAATCATTATT

Downstream 100 bases:

>100_bases
AAAAAAGCGGACATGGTTGACAGGAAAACCCTTTCAACTTTGCCCACAATACCCGCCAAGTCCATTTTACTCTTTCTCCC
CTTCCATCCTAAACGGAAAG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQPPLFSCGHVTFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRESDVIVALIPFQKGDEPIDRKFASELIEQWVKPTGKPFVIALNKADLVPEETAKEAQTEIISKYKPVATLALSA
LTGGNIPELVELLRPLLPFDEPIWPDDILSTEPERFFVGEIIREKIFLQYGREIPYSTEVVIDEFKEQHENNPSRKELIR
CSVIVERNSQKQIIVGQKGAAIKKLGQAARKEIEELLDRPVYLEIFVKVRPDWRKKKNLLKSYGY

Sequences:

>Translated_305_residues
MQPPLFSCGHVTFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRESDVIVALIPFQKGDEPIDRKFASELIEQWVKPTGKPFVIALNKADLVPEETAKEAQTEIISKYKPVATLALSA
LTGGNIPELVELLRPLLPFDEPIWPDDILSTEPERFFVGEIIREKIFLQYGREIPYSTEVVIDEFKEQHENNPSRKELIR
CSVIVERNSQKQIIVGQKGAAIKKLGQAARKEIEELLDRPVYLEIFVKVRPDWRKKKNLLKSYGY
>Mature_305_residues
MQPPLFSCGHVTFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRESDVIVALIPFQKGDEPIDRKFASELIEQWVKPTGKPFVIALNKADLVPEETAKEAQTEIISKYKPVATLALSA
LTGGNIPELVELLRPLLPFDEPIWPDDILSTEPERFFVGEIIREKIFLQYGREIPYSTEVVIDEFKEQHENNPSRKELIR
CSVIVERNSQKQIIVGQKGAAIKKLGQAARKEIEELLDRPVYLEIFVKVRPDWRKKKNLLKSYGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=326, Percent_Identity=24.5398773006135, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788919, Length=300, Percent_Identity=34.3333333333333, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI87082120, Length=185, Percent_Identity=28.1081081081081, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34755; Mature: 34755

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPPLFSCGHVTFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIII
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCEEECCCCEEEE
LDTPGIMDPKQSLHESMLEITRRSLRESDVIVALIPFQKGDEPIDRKFASELIEQWVKPT
EECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
GKPFVIALNKADLVPEETAKEAQTEIISKYKPVATLALSALTGGNIPELVELLRPLLPFD
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EPIWPDDILSTEPERFFVGEIIREKIFLQYGREIPYSTEVVIDEFKEQHENNPSRKELIR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
CSVIVERNSQKQIIVGQKGAAIKKLGQAARKEIEELLDRPVYLEIFVKVRPDWRKKKNLL
HHHEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHH
KSYGY
HHCCC
>Mature Secondary Structure
MQPPLFSCGHVTFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIII
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHCCEEECCCCEEEE
LDTPGIMDPKQSLHESMLEITRRSLRESDVIVALIPFQKGDEPIDRKFASELIEQWVKPT
EECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
GKPFVIALNKADLVPEETAKEAQTEIISKYKPVATLALSALTGGNIPELVELLRPLLPFD
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EPIWPDDILSTEPERFFVGEIIREKIFLQYGREIPYSTEVVIDEFKEQHENNPSRKELIR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHH
CSVIVERNSQKQIIVGQKGAAIKKLGQAARKEIEELLDRPVYLEIFVKVRPDWRKKKNLL
HHHEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHH
KSYGY
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA