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The map label for this gene is fruA [H]

Identifier: 21673074

GI number: 21673074

Start: 247342

End: 247845

Strand: Direct

Name: fruA [H]

Synonym: CT0235

Alternate gene names: 21673074

Gene position: 247342-247845 (Clockwise)

Preceding gene: 21673072

Following gene: 21673075

Centisome position: 11.48

GC content: 56.15

Gene sequence:

>504_bases
TTGCGTCCACACTCTGCAATGCTGTCATCGACCATGAAAATCGAAGCCCTTCTCACAGAAAAGCACATCAACCTGAATCT
CGGTTCCAGTTCAAAGGACGAGGTGATCGATACGCTGATCGCTATGGTGGCTGATCATGACAAGGTCAGGGATTTAAAGC
AGCTTGCCGAGGATGTACGAAAGCGGGAACGAGAGATGTCCACGGGCATCGGCAAGAACATCGGGTTGCCGCACGCCAAG
ACCTCGGCGGTGACCGAACCGGTGCTGGCACTCGCCACGCTTTCCAATGAGGTCGATTTTGAGTCGATCGACAACCAGCC
GGTGAAGATCGTGTTCCTGCTTGCCACGCCGGAGACCATGCTTGCCGAGCATCTCAAACTGCTCGGACGCATCACCAGGC
TTGCGGGCCGGGACGATGTTCGCCGCAAGCTCATCGACGCGGCAACCCCCGCAGATGTGCTCGAACTTTTCAAGCAGGAG
GAGAGGGATCTCCCCCAGATTTAA

Upstream 100 bases:

>100_bases
GCGGGTTTTCCCCGTTTTTGGCTACTCTGCCTTTTTTCGGTTCTGCGGCTCGCGGCCAGACAATCCGGCATGGTTCCCCG
GAGAATGCGGTTTCCCGATC

Downstream 100 bases:

>100_bases
TTTGATGACCGCAAGGCAGCTATGACACAGTTCCAAGGAGTGAAAGGGACGAGAGATATTTTTCCTGATGAGATTTCGAG
ATGGCACTATGTCGAGGGGG

Product: PTS system, IIA component

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MRPHSAMLSSTMKIEALLTEKHINLNLGSSSKDEVIDTLIAMVADHDKVRDLKQLAEDVRKREREMSTGIGKNIGLPHAK
TSAVTEPVLALATLSNEVDFESIDNQPVKIVFLLATPETMLAEHLKLLGRITRLAGRDDVRRKLIDAATPADVLELFKQE
ERDLPQI

Sequences:

>Translated_167_residues
MRPHSAMLSSTMKIEALLTEKHINLNLGSSSKDEVIDTLIAMVADHDKVRDLKQLAEDVRKREREMSTGIGKNIGLPHAK
TSAVTEPVLALATLSNEVDFESIDNQPVKIVFLLATPETMLAEHLKLLGRITRLAGRDDVRRKLIDAATPADVLELFKQE
ERDLPQI
>Mature_167_residues
MRPHSAMLSSTMKIEALLTEKHINLNLGSSSKDEVIDTLIAMVADHDKVRDLKQLAEDVRKREREMSTGIGKNIGLPHAK
TSAVTEPVLALATLSNEVDFESIDNQPVKIVFLLATPETMLAEHLKLLGRITRLAGRDDVRRKLIDAATPADVLELFKQE
ERDLPQI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=145, Percent_Identity=32.4137931034483, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI2367327, Length=118, Percent_Identity=25.4237288135593, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 18585; Mature: 18585

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHSAMLSSTMKIEALLTEKHINLNLGSSSKDEVIDTLIAMVADHDKVRDLKQLAEDVR
CCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KREREMSTGIGKNIGLPHAKTSAVTEPVLALATLSNEVDFESIDNQPVKIVFLLATPETM
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEECCHHH
LAEHLKLLGRITRLAGRDDVRRKLIDAATPADVLELFKQEERDLPQI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRPHSAMLSSTMKIEALLTEKHINLNLGSSSKDEVIDTLIAMVADHDKVRDLKQLAEDVR
CCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KREREMSTGIGKNIGLPHAKTSAVTEPVLALATLSNEVDFESIDNQPVKIVFLLATPETM
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEECCHHH
LAEHLKLLGRITRLAGRDDVRRKLIDAATPADVLELFKQEERDLPQI
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]