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The map label for this gene is cdsA [H]

Identifier: 21673072

GI number: 21673072

Start: 246276

End: 247097

Strand: Direct

Name: cdsA [H]

Synonym: CT0233

Alternate gene names: 21673072

Gene position: 246276-247097 (Clockwise)

Preceding gene: 21673071

Following gene: 21673074

Centisome position: 11.43

GC content: 59.61

Gene sequence:

>822_bases
GTGTTGATGCAAAGCAATCTCATGCAGAGAGTGGCGGTTGCCATTGTGGGCATTCCGCTGTTACTCTGGCTCAATATGCA
AGGTGGTTTGTATTTTCTGGGGCTGGTGCTCGCGCTCAGCCTCATGGCGACCTGGGAGTTCTGGCGCCTGGCCACGCATC
GGGCACATCCGCCGTCGGTTGTTATTCTGCTGCCGCTGACTGCCTTTGTGCAGCTCGATTTCTATTACGGCTTCATCGGC
TACTGGGAGGCGATTCTCGCCGTGGTCATGCTTCTGTATGTGCTTGAAATATGGCGGAACCAGGGTTCCCAGTTCATGAA
CCTCGGTGCGACGCTTGTCGGTCTGCTCTACGTGAACCTAAGCTTTGGTGCGTTGCTCAGGCTCCGCTTGTCGGAGACCA
CCGGCGAGGGTTCCGGCGAGGCGCTGGTGCTGCTCATGTTGCTGTGTGTCTGGGCGGCGGATATTTTCGCCTATTTCGGC
GGACGCGGATTCGGAGGCAAGTTTATCAAAAAGAGGCTCTTTGCGCGCATCAGCCCGAAGAAGACCTGGGAGGGCTATCT
TGCTGGAATTGCCGGAAGCGCGCTGGCGGCGTGGGCCTGCTCGGCGTACATCTCCGGCTGCCCCGACGGGCGGGCGATAC
CGGCGGGCCTGCTCATCGGCGTGGTCGCGCCCGCAGGCGACCTGCTCGAATCGATGTTCAAGCGTGATGCGGGAGTCAAG
GACTCATCGGGTGTCATTCCGGGGCACGGCGGTGTGCTTGACCGCTTTGATACCGTGATGTTCGTCTCCCCGCTGCTCTA
TTTCCTCGTGCATCACTGGTGA

Upstream 100 bases:

>100_bases
CGTTGTCTCTTTTTTTTCTGCTGATCCGGTATTTTCCGGTGAGGCCGGCATTGCAGGATGCCGATAACCCGATGCCTCCC
GGGCATCGCTGGAAATCTCA

Downstream 100 bases:

>100_bases
TCTTTCACCGGTTGATGCCGGTACATAAAAGAATGTTTTTCTTATATTCCGGTTTTGTTTTTAGAGGAACTCCTCTGTTG
ACGGTATCGTGATCTTCGGT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLMQSNLMQRVAVAIVGIPLLLWLNMQGGLYFLGLVLALSLMATWEFWRLATHRAHPPSVVILLPLTAFVQLDFYYGFIG
YWEAILAVVMLLYVLEIWRNQGSQFMNLGATLVGLLYVNLSFGALLRLRLSETTGEGSGEALVLLMLLCVWAADIFAYFG
GRGFGGKFIKKRLFARISPKKTWEGYLAGIAGSALAAWACSAYISGCPDGRAIPAGLLIGVVAPAGDLLESMFKRDAGVK
DSSGVIPGHGGVLDRFDTVMFVSPLLYFLVHHW

Sequences:

>Translated_273_residues
MLMQSNLMQRVAVAIVGIPLLLWLNMQGGLYFLGLVLALSLMATWEFWRLATHRAHPPSVVILLPLTAFVQLDFYYGFIG
YWEAILAVVMLLYVLEIWRNQGSQFMNLGATLVGLLYVNLSFGALLRLRLSETTGEGSGEALVLLMLLCVWAADIFAYFG
GRGFGGKFIKKRLFARISPKKTWEGYLAGIAGSALAAWACSAYISGCPDGRAIPAGLLIGVVAPAGDLLESMFKRDAGVK
DSSGVIPGHGGVLDRFDTVMFVSPLLYFLVHHW
>Mature_273_residues
MLMQSNLMQRVAVAIVGIPLLLWLNMQGGLYFLGLVLALSLMATWEFWRLATHRAHPPSVVILLPLTAFVQLDFYYGFIG
YWEAILAVVMLLYVLEIWRNQGSQFMNLGATLVGLLYVNLSFGALLRLRLSETTGEGSGEALVLLMLLCVWAADIFAYFG
GRGFGGKFIKKRLFARISPKKTWEGYLAGIAGSALAAWACSAYISGCPDGRAIPAGLLIGVVAPAGDLLESMFKRDAGVK
DSSGVIPGHGGVLDRFDTVMFVSPLLYFLVHHW

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=196, Percent_Identity=36.2244897959184, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787677, Length=121, Percent_Identity=34.7107438016529, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29868; Mature: 29868

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]