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The map label for this gene is hslV [H]

Identifier: 21672817

GI number: 21672817

Start: 612947

End: 613477

Strand: Direct

Name: hslV [H]

Synonym: BUsg557

Alternate gene names: 21672817

Gene position: 612947-613477 (Clockwise)

Preceding gene: 21672815

Following gene: 21672818

Centisome position: 95.56

GC content: 31.83

Gene sequence:

>531_bases
GTGACCACAATACTCAGTGTAAGATTAAAAAATAAAGTAGTAATTGGAGGTGATGGACAAGCTACTTTAGGCAATACTAT
TATGAAAAGTAATGTTAAAAAAATCAGAACACTTTATCATGAAAAGGTGATTGCTGGTTTTGCAGGTGGAACTGCAGATG
CTTTCACTTTATTTGAAATGTTTGAAAAAAAATTAGCTATGTATCAGGGTCAATTGCCACGTGCTGCTATTGAATTAGCA
AAAGATTGGAGATCTGATAGAATGTTACGTAAATTAGAAGCTTTGTTAGCAGTTGCTGATAAAGACACTTCATTAATTAT
TACTGGAAATGGCGATGTGATACAGCCTGAAGATGATTTAATTGCAATAGGTTCTGGTGGATCTTATGCTCAATCTGCAG
CACGTGCATTAATTAATAATACTACACTCAACGCTGATGAAATCGTAGAAAAATCATTAAATATTGCAGCAAATATTTGT
ATATATACCAATCATAGTTTTACTATAAAAGAACTATTTTCAGAAAAATAA

Upstream 100 bases:

>100_bases
CATATAAATTAAAGTTATAACGCTCAATTTGTTTTATTATAAATTTTATTTTTTATATAATTAAAAAAATAAACACATTA
TTTTTTAAGAGGTTTTTCTT

Downstream 100 bases:

>100_bases
GGATTATTTATATGTCTGAAATGACACCCCCTCAAATTGTTTCTGAACTTAATAAATTTATTATTGGTCAAGAACAAGCA
AAAAAAGCTGTTGCTATTGC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MTTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEMFEKKLAMYQGQLPRAAIELA
KDWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDLIAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANIC
IYTNHSFTIKELFSEK

Sequences:

>Translated_176_residues
MTTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEMFEKKLAMYQGQLPRAAIELA
KDWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDLIAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANIC
IYTNHSFTIKELFSEK
>Mature_175_residues
TTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEMFEKKLAMYQGQLPRAAIELAK
DWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDLIAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANICI
YTNHSFTIKELFSEK

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=76.1627906976744, Blast_Score=274, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19181; Mature: 19050

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEM
CCEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FEKKLAMYQGQLPRAAIELAKDWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCE
IAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANICIYTNHSFTIKELFSEK
EEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEEECCCEEHHHHHCCC
>Mature Secondary Structure 
TTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEM
CEEEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FEKKLAMYQGQLPRAAIELAKDWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCE
IAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANICIYTNHSFTIKELFSEK
EEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEEEECCCEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]