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The map label for this gene is cyoA

Identifier: 21672721

GI number: 21672721

Start: 517907

End: 518779

Strand: Reverse

Name: cyoA

Synonym: BUsg456

Alternate gene names: 21672721

Gene position: 518779-517907 (Counterclockwise)

Preceding gene: 21672728

Following gene: 21672720

Centisome position: 80.88

GC content: 23.37

Gene sequence:

>873_bases
ATGATATCTATAAATTTTAATAATTTTTTTAAGACATTATTATTAATTTTAATTGCTTTTACATTACACGGTTGCGATAG
TATTTTGTTCAATCCTCATGGAATAATTGCGATACAAGAATGTTCAATATTATTAATATCTTTTTTAATAATGCTGTTTG
TTATAATACCTGTAATTTTTATGACTATATATTTTTCAGTTAAATATCGTGCATCTAATATAAATGCAAAATATAAACCA
GATTGGTGCGATTCTAAAAAAATAGAAATAATAGTATGGACAATTCCGATTTCAATAATTTTATTTTTGGCTTTTGTGAC
ATGGAATTATAGTCATATATTAGATCCTAAAAAATCTATTATTTCTAAATATAAGCCTATAAAAATAGATGTTGTATCAT
TAGACTGGAGATGGCTATTTATTTATCCTGAATATCATATAGCAACTATTAACGAAATTATGTTTCCTATAAATAGATCT
ATAATTTTTCATATTACTTCTAATTCTGTTATGAATTCTTTCTTTATTCCGTCTCTTGGTAGTCAAATATATGCTATGCC
TGGAATGATGACTACATTGAATTTAATGTCTAATTCTCCCGGAAAATATAAAGGGATATCATCTAATTACAGTGGTAAGG
GTTTTTCTAATATGAAATTTACTGCAATATCTGTTTTGAATATAAAAGACTTTGAAAATTGGATTAAAAAAGCACAACAA
TCTCCTAAAAAATTAAATAAAATGAGTATTTTTAACATCATTTCTTTACCTAACGAAAATCATTTCATAGAATATTTTTC
TGATGTTAAAAAAAATTTATTTTATGAGATAATTAATCAAACTTATTCAAAGAATAAAGTATTCAAACATTAG

Upstream 100 bases:

>100_bases
ATTTACATTAAATAAAAAATTTAATTGAAATTTAATATAAAAATAATATTTTTAAGAGAAAAATTTTTAATAATAAATAT
TATATTTGAGGTTTTTTTTG

Downstream 100 bases:

>100_bases
AAAAATTTATATAAAATATTAGGCGTATGAGGAAATACAATGTTTGGAAAATTAACATTAAAAGCTATACCTGTTGATGA
ACCAATTATAATGGTTACAT

Product: cytochrome O ubiquinol oxidase A

Products: NA

Alternate protein names: Cytochrome o subunit 2; Cytochrome o ubiquinol oxidase subunit 2; Oxidase BO(3) subunit 2; Ubiquinol oxidase polypeptide II

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MISINFNNFFKTLLLILIAFTLHGCDSILFNPHGIIAIQECSILLISFLIMLFVIIPVIFMTIYFSVKYRASNINAKYKP
DWCDSKKIEIIVWTIPISIILFLAFVTWNYSHILDPKKSIISKYKPIKIDVVSLDWRWLFIYPEYHIATINEIMFPINRS
IIFHITSNSVMNSFFIPSLGSQIYAMPGMMTTLNLMSNSPGKYKGISSNYSGKGFSNMKFTAISVLNIKDFENWIKKAQQ
SPKKLNKMSIFNIISLPNENHFIEYFSDVKKNLFYEIINQTYSKNKVFKH

Sequences:

>Translated_290_residues
MISINFNNFFKTLLLILIAFTLHGCDSILFNPHGIIAIQECSILLISFLIMLFVIIPVIFMTIYFSVKYRASNINAKYKP
DWCDSKKIEIIVWTIPISIILFLAFVTWNYSHILDPKKSIISKYKPIKIDVVSLDWRWLFIYPEYHIATINEIMFPINRS
IIFHITSNSVMNSFFIPSLGSQIYAMPGMMTTLNLMSNSPGKYKGISSNYSGKGFSNMKFTAISVLNIKDFENWIKKAQQ
SPKKLNKMSIFNIISLPNENHFIEYFSDVKKNLFYEIINQTYSKNKVFKH
>Mature_290_residues
MISINFNNFFKTLLLILIAFTLHGCDSILFNPHGIIAIQECSILLISFLIMLFVIIPVIFMTIYFSVKYRASNINAKYKP
DWCDSKKIEIIVWTIPISIILFLAFVTWNYSHILDPKKSIISKYKPIKIDVVSLDWRWLFIYPEYHIATINEIMFPINRS
IIFHITSNSVMNSFFIPSLGSQIYAMPGMMTTLNLMSNSPGKYKGISSNYSGKGFSNMKFTAISVLNIKDFENWIKKAQQ
SPKKLNKMSIFNIISLPNENHFIEYFSDVKKNLFYEIINQTYSKNKVFKH

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family

Homologues:

Organism=Escherichia coli, GI1786635, Length=281, Percent_Identity=50.5338078291815, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYOA_BUCAP (Q8K993)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660788.1
- ProteinModelPortal:   Q8K993
- SMR:   Q8K993
- EnsemblBacteria:   EBBUCT00000000458
- GeneID:   1005709
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg456
- GeneTree:   EBGT00050000008135
- HOGENOM:   HBG313936
- OMA:   WKSTHEL
- ProtClustDB:   CLSK316278
- BioCyc:   BAPH198804:BUSG456-MONOMER
- InterPro:   IPR012141
- InterPro:   IPR010514
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR006333
- Gene3D:   G3DSA:1.10.287.90
- Gene3D:   G3DSA:2.60.40.420
- PANTHER:   PTHR22888
- PIRSF:   PIRSF000292
- TIGRFAMs:   TIGR01433

Pfam domain/function: PF00116 COX2; PF06481 COX_ARM; SSF49503 Cupredoxin; SSF81464 Cyt_c_oxidase_II-like_TM

EC number: 1.10.3.-

Molecular weight: Translated: 33730; Mature: 33730

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50857 COX2_CUA; PS50999 COX2_TM; PS51257 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc0241d0)-; HASH(0xcac2884)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISINFNNFFKTLLLILIAFTLHGCDSILFNPHGIIAIQECSILLISFLIMLFVIIPVIF
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
MTIYFSVKYRASNINAKYKPDWCDSKKIEIIVWTIPISIILFLAFVTWNYSHILDPKKSI
HHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHCCCHHHH
ISKYKPIKIDVVSLDWRWLFIYPEYHIATINEIMFPINRSIIFHITSNSVMNSFFIPSLG
HHCCCCEEEEEEEEEEEEEEEECCCEEHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCCC
SQIYAMPGMMTTLNLMSNSPGKYKGISSNYSGKGFSNMKFTAISVLNIKDFENWIKKAQQ
CCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHC
SPKKLNKMSIFNIISLPNENHFIEYFSDVKKNLFYEIINQTYSKNKVFKH
CHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MISINFNNFFKTLLLILIAFTLHGCDSILFNPHGIIAIQECSILLISFLIMLFVIIPVIF
CEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
MTIYFSVKYRASNINAKYKPDWCDSKKIEIIVWTIPISIILFLAFVTWNYSHILDPKKSI
HHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHCCCHHHH
ISKYKPIKIDVVSLDWRWLFIYPEYHIATINEIMFPINRSIIFHITSNSVMNSFFIPSLG
HHCCCCEEEEEEEEEEEEEEEECCCEEHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCCC
SQIYAMPGMMTTLNLMSNSPGKYKGISSNYSGKGFSNMKFTAISVLNIKDFENWIKKAQQ
CCEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHC
SPKKLNKMSIFNIISLPNENHFIEYFSDVKKNLFYEIINQTYSKNKVFKH
CHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438