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The map label for this gene is cyoB

Identifier: 21672720

GI number: 21672720

Start: 515888

End: 517867

Strand: Reverse

Name: cyoB

Synonym: BUsg455

Alternate gene names: 21672720

Gene position: 517867-515888 (Counterclockwise)

Preceding gene: 21672721

Following gene: 21672719

Centisome position: 80.73

GC content: 29.19

Gene sequence:

>1980_bases
ATGTTTGGAAAATTAACATTAAAAGCTATACCTGTTGATGAACCAATTATAATGGTTACATATATTTCTATTATTCTAAT
TGCACTATTTATTTCTTTTAGTATTACTTACTTTAAAAAATGGAAATATTTATGGTATGAGTGGTTTACCACAGTTGACC
ATAAAAAAATATCTATTATGTATGGAATACTTGCATTCATTATGTTATTTCGTGGTTTCGTTGATGCAATATTAATGCGT
ACCCAACAGGTCATTGCATCTTCAGGTAATACAGGTTTTTTACCACCTCATCATTATGATCAAATATTTACGGCTCATGG
TGTCATAATGATTTTTTTTGTAGCTATGCCACTTGTAATTGGACTAATGAATTTAGTTGTTCCATTACAAATTGGAGCTC
GCGATGTAGCTTTTCCTTTTCTTAATAATTTAAGTTTTTGGTTGAATGTTAGTGGTGCTATTTTGCTTACTCTTTCTTTA
GGAATAGGTGAATTTGCACAAACAGGATGGTTAGCTTATCCTCCATTATCTGAAGTTAAATATAGTCCAGGAGTAGGTGT
AGATTACTGGATTTGGAGTCTTCAAATTTCTGGTGTTGGGACTACTTTAACAGGTATTAATTTTTTAATAACAATTTTAA
AAATGAGAGCACCAGGAATGTGTTTTTTTAAAATGCCAGTTTTTACTTGGGCTGCTTTATGTACTAATATTCTTATTGTC
ATTTCTTTTCCAGTTTTGACTACTACTCTTTTATTACTAACATTAGATCGTTGTTTTGATTTTCATTTCTTTACTAATAA
TTTTGGTGGAAATCCAATGATGTATGTTAACTTAATATGGATTTGGGGTCATCCAGAAGTCTATATTTTAGTTCTTCCAG
TATTTGGTGTATTTTCAGAAGTAGTTGCTACTTTTTCAAAAAAACGTTTATTTGGATACGTATCCTTAGTTTGGGCAACT
TTAGCTATTACTATTTTGTCTTTTATCGTTTGGCTTCACCATTTTTTTACTATGGGTGCTGGTTCAAATGTTAATGCTTT
TTTTGGCATTACTACTATGATTATAGCTATTCCTACTGGAGTAAAAATTTTTAATTGGTTATTTACAATGTATCAAGGTC
GTGTTCATATGCATTCTTCTATGCTATGGACTATTGGATTTTTGATTACTTTTTCTATTGGTGGAATGACAGGTGTACTG
TTATCTATTCCTCCTGCTGATTTCATTTTGCATAATAGTTTATTTTTAGTTGCTCATTTTCATAATGTCATTATTGGTGG
TGTTGTTTTTGGTTGTTTTGCTGGCATTAATTATTGGTTTCCTAAATTATTTGGTTTTATTTTAAATGAATTATGGGGTA
AGCGTGCTTTTTGGTTTTGGATCATAGGTTTTTTTACTGCTTTTATGCCATTATATTTTTTAGGTTTTATGGGAATGACT
CGTCGTCTAAGTCAAAATATTGATATTGAATTTCATTTTTTATTATCTATTGCTGCTATTGGTGCTATTCTTATTGGTAT
AGGTATACTTTGTCAAATCATTCAATTTTGGGTTTCAGTAAGAGATCGTCATATTAATTTAGATGTTACTGGTGATCCAT
GGGATGGAAGAACTTTAGAATGGTCTACTTCTTCTCCTGCTCCATTATATAATTTTGCTATTATCCCTCATATTAAAAAC
AAAGATGATTTTTGGGAACTAAAAAAACAAAAGAATCAAGTTCAAAAAAAACAATACAGTGCAATTCATATGCCTAAAAA
TACAGGATTAGGTATATTTATTAGTTTTTTTTCTTTACTTTTTGGTTTTTCTGCAGTATGGAATATTATTTGGTTATCTT
TTTTATCTTTTTTAGTTGTTATTATAAGTTTAATTTTTAAAAGTATAGATGAAAATACTGAATATACTGTATCAGTAAAA
GAGATTGAAAGTATTGAAAATCGACACTTAGAAAATGTTCAAAAAGCAGGTTTAAAATGA

Upstream 100 bases:

>100_bases
AAATTTATTTTATGAGATAATTAATCAAACTTATTCAAAGAATAAAGTATTCAAACATTAGAAAAATTTATATAAAATAT
TAGGCGTATGAGGAAATACA

Downstream 100 bases:

>100_bases
TAAAAGAAACAATGAGAAATAATAAACTATTCGGCTTGTGGATATATTTGATGAGCGATTGTATCATATTCGCTGTTCTT
TTTGCAGTATATGCTATTAT

Product: cytochrome O ubiquinol oxidase B

Products: NA

Alternate protein names: Cytochrome o subunit 1; Cytochrome o ubiquinol oxidase subunit 1; Oxidase BO(3) subunit 1; Ubiquinol oxidase polypeptide I

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MFGKLTLKAIPVDEPIIMVTYISIILIALFISFSITYFKKWKYLWYEWFTTVDHKKISIMYGILAFIMLFRGFVDAILMR
TQQVIASSGNTGFLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNLVVPLQIGARDVAFPFLNNLSFWLNVSGAILLTLSL
GIGEFAQTGWLAYPPLSEVKYSPGVGVDYWIWSLQISGVGTTLTGINFLITILKMRAPGMCFFKMPVFTWAALCTNILIV
ISFPVLTTTLLLLTLDRCFDFHFFTNNFGGNPMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFSKKRLFGYVSLVWAT
LAITILSFIVWLHHFFTMGAGSNVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRVHMHSSMLWTIGFLITFSIGGMTGVL
LSIPPADFILHNSLFLVAHFHNVIIGGVVFGCFAGINYWFPKLFGFILNELWGKRAFWFWIIGFFTAFMPLYFLGFMGMT
RRLSQNIDIEFHFLLSIAAIGAILIGIGILCQIIQFWVSVRDRHINLDVTGDPWDGRTLEWSTSSPAPLYNFAIIPHIKN
KDDFWELKKQKNQVQKKQYSAIHMPKNTGLGIFISFFSLLFGFSAVWNIIWLSFLSFLVVIISLIFKSIDENTEYTVSVK
EIESIENRHLENVQKAGLK

Sequences:

>Translated_659_residues
MFGKLTLKAIPVDEPIIMVTYISIILIALFISFSITYFKKWKYLWYEWFTTVDHKKISIMYGILAFIMLFRGFVDAILMR
TQQVIASSGNTGFLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNLVVPLQIGARDVAFPFLNNLSFWLNVSGAILLTLSL
GIGEFAQTGWLAYPPLSEVKYSPGVGVDYWIWSLQISGVGTTLTGINFLITILKMRAPGMCFFKMPVFTWAALCTNILIV
ISFPVLTTTLLLLTLDRCFDFHFFTNNFGGNPMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFSKKRLFGYVSLVWAT
LAITILSFIVWLHHFFTMGAGSNVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRVHMHSSMLWTIGFLITFSIGGMTGVL
LSIPPADFILHNSLFLVAHFHNVIIGGVVFGCFAGINYWFPKLFGFILNELWGKRAFWFWIIGFFTAFMPLYFLGFMGMT
RRLSQNIDIEFHFLLSIAAIGAILIGIGILCQIIQFWVSVRDRHINLDVTGDPWDGRTLEWSTSSPAPLYNFAIIPHIKN
KDDFWELKKQKNQVQKKQYSAIHMPKNTGLGIFISFFSLLFGFSAVWNIIWLSFLSFLVVIISLIFKSIDENTEYTVSVK
EIESIENRHLENVQKAGLK
>Mature_659_residues
MFGKLTLKAIPVDEPIIMVTYISIILIALFISFSITYFKKWKYLWYEWFTTVDHKKISIMYGILAFIMLFRGFVDAILMR
TQQVIASSGNTGFLPPHHYDQIFTAHGVIMIFFVAMPLVIGLMNLVVPLQIGARDVAFPFLNNLSFWLNVSGAILLTLSL
GIGEFAQTGWLAYPPLSEVKYSPGVGVDYWIWSLQISGVGTTLTGINFLITILKMRAPGMCFFKMPVFTWAALCTNILIV
ISFPVLTTTLLLLTLDRCFDFHFFTNNFGGNPMMYVNLIWIWGHPEVYILVLPVFGVFSEVVATFSKKRLFGYVSLVWAT
LAITILSFIVWLHHFFTMGAGSNVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRVHMHSSMLWTIGFLITFSIGGMTGVL
LSIPPADFILHNSLFLVAHFHNVIIGGVVFGCFAGINYWFPKLFGFILNELWGKRAFWFWIIGFFTAFMPLYFLGFMGMT
RRLSQNIDIEFHFLLSIAAIGAILIGIGILCQIIQFWVSVRDRHINLDVTGDPWDGRTLEWSTSSPAPLYNFAIIPHIKN
KDDFWELKKQKNQVQKKQYSAIHMPKNTGLGIFISFFSLLFGFSAVWNIIWLSFLSFLVVIISLIFKSIDENTEYTVSVK
EIESIENRHLENVQKAGLK

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration. This ubiquinol oxidase shows proton pump activity across the membrane in addition to the electron transfer

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family

Homologues:

Organism=Homo sapiens, GI251831109, Length=516, Percent_Identity=38.3720930232558, Blast_Score=326, Evalue=4e-89,
Organism=Escherichia coli, GI1786634, Length=660, Percent_Identity=72.4242424242424, Blast_Score=1008, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6226519, Length=447, Percent_Identity=40.2684563758389, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6226524, Length=326, Percent_Identity=41.1042944785276, Blast_Score=242, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=33.4661354581673, Blast_Score=131, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYOB_BUCAP (Q8K994)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660787.1
- ProteinModelPortal:   Q8K994
- SMR:   Q8K994
- EnsemblBacteria:   EBBUCT00000000515
- GeneID:   1005710
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg455
- GeneTree:   EBGT00050000007935
- HOGENOM:   HBG603668
- OMA:   RSYDRDV
- ProtClustDB:   CLSK435874
- BioCyc:   BAPH198804:BUSG455-MONOMER
- InterPro:   IPR000883
- InterPro:   IPR014207
- Gene3D:   G3DSA:1.20.210.10
- PANTHER:   PTHR10422
- PRINTS:   PR01165
- TIGRFAMs:   TIGR02843

Pfam domain/function: PF00115 COX1; SSF81442 COX1

EC number: 1.10.3.-

Molecular weight: Translated: 75029; Mature: 75029

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50855 COX1; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc856350)-; HASH(0xcb80fe8)-; HASH(0xbc60584)-; HASH(0xbef86d0)-; HASH(0xc1cca40)-; HASH(0xc8ae74c)-; HASH(0xc44d6d8)-; HASH(0xcc036c4)-; HASH(0xb6f90c8)-; HASH(0x40481284)-; HASH(0xb957a90)-; HASH(0xb324828)-; HASH(0xbfb31dc)-; HASH(0xc27d81c)-; HASH(0xbf8cc08)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLTLKAIPVDEPIIMVTYISIILIALFISFSITYFKKWKYLWYEWFTTVDHKKISIM
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YGILAFIMLFRGFVDAILMRTQQVIASSGNTGFLPPHHYDQIFTAHGVIMIFFVAMPLVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFLNNLSFWLNVSGAILLTLSLGIGEFAQTGWLAYPPLSEVK
HHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCEEEEEEECCCCHHHHCCCEECCCHHHCC
YSPGVGVDYWIWSLQISGVGTTLTGINFLITILKMRAPGMCFFKMPVFTWAALCTNILIV
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
ISFPVLTTTLLLLTLDRCFDFHFFTNNFGGNPMMYVNLIWIWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHH
VVATFSKKRLFGYVSLVWATLAITILSFIVWLHHFFTMGAGSNVNAFFGITTMIIAIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
VKIFNWLFTMYQGRVHMHSSMLWTIGFLITFSIGGMTGVLLSIPPADFILHNSLFLVAHF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHCCHHHHHHH
HNVIIGGVVFGCFAGINYWFPKLFGFILNELWGKRAFWFWIIGFFTAFMPLYFLGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQNIDIEFHFLLSIAAIGAILIGIGILCQIIQFWVSVRDRHINLDVTGDPWDGRTLE
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEE
WSTSSPAPLYNFAIIPHIKNKDDFWELKKQKNQVQKKQYSAIHMPKNTGLGIFISFFSLL
ECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHH
FGFSAVWNIIWLSFLSFLVVIISLIFKSIDENTEYTVSVKEIESIENRHLENVQKAGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MFGKLTLKAIPVDEPIIMVTYISIILIALFISFSITYFKKWKYLWYEWFTTVDHKKISIM
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YGILAFIMLFRGFVDAILMRTQQVIASSGNTGFLPPHHYDQIFTAHGVIMIFFVAMPLVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLMNLVVPLQIGARDVAFPFLNNLSFWLNVSGAILLTLSLGIGEFAQTGWLAYPPLSEVK
HHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCEEEEEEECCCCHHHHCCCEECCCHHHCC
YSPGVGVDYWIWSLQISGVGTTLTGINFLITILKMRAPGMCFFKMPVFTWAALCTNILIV
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
ISFPVLTTTLLLLTLDRCFDFHFFTNNFGGNPMMYVNLIWIWGHPEVYILVLPVFGVFSE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHH
VVATFSKKRLFGYVSLVWATLAITILSFIVWLHHFFTMGAGSNVNAFFGITTMIIAIPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
VKIFNWLFTMYQGRVHMHSSMLWTIGFLITFSIGGMTGVLLSIPPADFILHNSLFLVAHF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHCCHHHHHHH
HNVIIGGVVFGCFAGINYWFPKLFGFILNELWGKRAFWFWIIGFFTAFMPLYFLGFMGMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLSQNIDIEFHFLLSIAAIGAILIGIGILCQIIQFWVSVRDRHINLDVTGDPWDGRTLE
HHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEE
WSTSSPAPLYNFAIIPHIKNKDDFWELKKQKNQVQKKQYSAIHMPKNTGLGIFISFFSLL
ECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHH
FGFSAVWNIIWLSFLSFLVVIISLIFKSIDENTEYTVSVKEIESIENRHLENVQKAGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Protoheme IX (Heme B55 and B562); Copper B. [C]

Metal ions: Fe; Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438