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The map label for this gene is ribD2

Identifier: 21672711

GI number: 21672711

Start: 508664

End: 509317

Strand: Direct

Name: ribD2

Synonym: BUsg446

Alternate gene names: 21672711

Gene position: 508664-509317 (Clockwise)

Preceding gene: 21672710

Following gene: 30410822

Centisome position: 79.3

GC content: 23.55

Gene sequence:

>654_bases
ATGTCGATAGATGGAAGAATAGCTATGAAAAATGGAGAAAGTCGATGGATTACTTCAAAAGAATCACGTGAAGATGTGCA
AAAATTCCGTGCAAAAAGTTCAGCTATTCTTACTAGTAGTGCTACTATATTAAATGATGATCCTTTACTGAATGTACGTT
ATAAAAAATTTGATAAAAATACATTATCTACTTTTCCTAAAAAAATATTTCAACAGCCTATAAGGATCATTATAGACAGT
AAAAATCGTGTTAAAAAATCACATAAAATAATACAAACAAAAGAAAAAATTTTATTAATGAGATTAAAATTAGATAAAGA
AATATGGCCAGAAAATACAAAACAAATTATAATAAAACCGTATAAAGAAAATATTGATTTATTATGTGTTTTAAAATTTT
TAGGAAATTTAGAAATTAACAATTTATGGATAGAAGCAGGAAGTACTTTATCTGGTTGTTTTTTAAAACTAGAATTAATT
GATGAAATTATTATATATATAGCACCAAAAATATTAGGACATGAGGCGAAACCATTATTTATATTTAATAATCAATTAAA
ATTGTTTGATTGTCTTAAATTTGATTTTAAAGACATTCGTCAAATAGGACCTGATATACGAATAAAATTAGAGCCTAAAA
ATAAAAAATTTTAA

Upstream 100 bases:

>100_bases
CGTAAAAATAGGTCTCATGTCAAAAGAATCTCAAAAATATAACAAAGGATTTTTTAAGAGAATGAGAACAGGATTACCAT
GAATACGACTAAAATTAGCA

Downstream 100 bases:

>100_bases
AATAAAGTATAATTGAGAAAACAAATGATAATAAAACCAAATTTTCGAAGAAAAGCTCGCGCCTGTGCTTTACAAATGTT
ATATTCTTGGGAAATTTCTC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: HTP reductase

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKNTLSTFPKKIFQQPIRIIIDS
KNRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKPYKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELI
DEIIIYIAPKILGHEAKPLFIFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF

Sequences:

>Translated_217_residues
MSIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKNTLSTFPKKIFQQPIRIIIDS
KNRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKPYKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELI
DEIIIYIAPKILGHEAKPLFIFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF
>Mature_216_residues
SIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKNTLSTFPKKIFQQPIRIIIDSK
NRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKPYKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELID
EIIIYIAPKILGHEAKPLFIFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTP reductase family

Homologues:

Organism=Escherichia coli, GI1786616, Length=209, Percent_Identity=46.88995215311, Blast_Score=221, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBD2_BUCAP (Q8K9A3)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660778.1
- ProteinModelPortal:   Q8K9A3
- SMR:   Q8K9A3
- EnsemblBacteria:   EBBUCT00000000062
- GeneID:   1005430
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg446
- GeneTree:   EBGT00050000007899
- HOGENOM:   HBG366223
- OMA:   WISSADS
- ProtClustDB:   CLSK316268
- BioCyc:   BAPH198804:BUSG446-MONOMER
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734
- PANTHER:   PTHR11079:SF10
- TIGRFAMs:   TIGR00326
- TIGRFAMs:   TIGR00227

Pfam domain/function: PF01872 RibD_C

EC number: =1.1.1.193

Molecular weight: Translated: 25345; Mature: 25214

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: BINDING 14-14 BINDING 16-16 BINDING 30-30 BINDING 46-46 BINDING 50-50 BINDING 53-53 BINDING 80-80 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKN
CCCCCEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEECCCEEECCCCEEEEEEECCCCH
TLSTFPKKIFQQPIRIIIDSKNRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKP
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEEE
YKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELIDEIIIYIAPKILGHEAKPLF
CCCCCCCEEEEHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF
EECCCEEEEHHHHCCHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKN
CCCCEEEEECCCCCEECCCHHHHHHHHHHHHCCEEEECCCEEECCCCEEEEEEECCCCH
TLSTFPKKIFQQPIRIIIDSKNRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKP
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEEE
YKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELIDEIIIYIAPKILGHEAKPLF
CCCCCCCEEEEHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF
EECCCEEEEHHHHCCHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438