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The map label for this gene is dapD

Identifier: 21672504

GI number: 21672504

Start: 254426

End: 255247

Strand: Reverse

Name: dapD

Synonym: BUsg223

Alternate gene names: 21672504

Gene position: 255247-254426 (Counterclockwise)

Preceding gene: 21672505

Following gene: 21672502

Centisome position: 39.79

GC content: 29.56

Gene sequence:

>822_bases
ATGAAAAAATATTATGACATTATCGAAAACGCTTATTTAAAAAAAAATGAAGTCAATACTAAAAATATTGATATTGAAAC
AAAACAAACAATTCATCATGTTATTGAATTATTAAATAGCGGGAAAATTAGAGTTGCAGAAAAAAAAGACAATATATGGA
TTACAAATCAATGGATAAAAAAAAGCATTTTATTGTATATGTATTTAAATCAAAATAACGTATTTCAAGGAAGTTTCAGT
AACTATTACGACAAAATTCCTCTTAAATATGAAAATTACAATGAAAAAAAATTTAAAGAAGAAAGAATTCGTGTAGTTCC
ACCAGCTACAATTAGGTATGGTTCATTTATTAATTCTAATACTATTATCATGCCATCATATGTCAATATTGGTGCATATG
TAGATCAAGGAACTATGATAGATACTTGGACCACGGTAGGTTCTTGTGCTCAAATTGGGAAAAATGTGCATTTATCTGGA
GGTGTAGGCATAGGAGGTGTTTTAGAACCTCTACAAAATAATCCTACAATTATTGAGGATAACTGTTTTATTGGAGCACG
CTCCGAAATAGTAGAGGGAGTAATCATAGAAGAAGGATCAGTGATCTCTATGGGAGTCTTTATAGGGCAAAGTACTAAAA
TTTATAATAGAGAAACAGGAGAAATTCTATATGGAAGGGTACCAGCTAACTCTGTAGTTGTTTCTGGAAGTTTACCATCA
AAAGATAGAAAATATAATCTGTATGCTGCCGTTATTGTTAAACGAGTAGACTCTAAAACACTTAATAAAGTAGAAATAAA
TCAACTTTTGCGTGATAAATAG

Upstream 100 bases:

>100_bases
TTAACATGGCAAAAAAATGAAAAAATTCCATCTAAGTTTATTAATAAATGATTAATCTATTAAAAATTTAATAAAATATT
AAATTAGGTCAATTTAAAAA

Downstream 100 bases:

>100_bases
AAAAATGAAAACCGCCCGGTGATTATATCGGGCGGAACAATAAAGTAGTTATTCACTAACTAAGTAAATACTATTATTCC
CTCTCTTCACACTAAAAACT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKKYYDIIENAYLKKNEVNTKNIDIETKQTIHHVIELLNSGKIRVAEKKDNIWITNQWIKKSILLYMYLNQNNVFQGSFS
NYYDKIPLKYENYNEKKFKEERIRVVPPATIRYGSFINSNTIIMPSYVNIGAYVDQGTMIDTWTTVGSCAQIGKNVHLSG
GVGIGGVLEPLQNNPTIIEDNCFIGARSEIVEGVIIEEGSVISMGVFIGQSTKIYNRETGEILYGRVPANSVVVSGSLPS
KDRKYNLYAAVIVKRVDSKTLNKVEINQLLRDK

Sequences:

>Translated_273_residues
MKKYYDIIENAYLKKNEVNTKNIDIETKQTIHHVIELLNSGKIRVAEKKDNIWITNQWIKKSILLYMYLNQNNVFQGSFS
NYYDKIPLKYENYNEKKFKEERIRVVPPATIRYGSFINSNTIIMPSYVNIGAYVDQGTMIDTWTTVGSCAQIGKNVHLSG
GVGIGGVLEPLQNNPTIIEDNCFIGARSEIVEGVIIEEGSVISMGVFIGQSTKIYNRETGEILYGRVPANSVVVSGSLPS
KDRKYNLYAAVIVKRVDSKTLNKVEINQLLRDK
>Mature_273_residues
MKKYYDIIENAYLKKNEVNTKNIDIETKQTIHHVIELLNSGKIRVAEKKDNIWITNQWIKKSILLYMYLNQNNVFQGSFS
NYYDKIPLKYENYNEKKFKEERIRVVPPATIRYGSFINSNTIIMPSYVNIGAYVDQGTMIDTWTTVGSCAQIGKNVHLSG
GVGIGGVLEPLQNNPTIIEDNCFIGARSEIVEGVIIEEGSVISMGVFIGQSTKIYNRETGEILYGRVPANSVVVSGSLPS
KDRKYNLYAAVIVKRVDSKTLNKVEINQLLRDK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=67.1586715867159, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_BUCAP (O85290)

Other databases:

- EMBL:   AE013218
- EMBL:   AF060492
- RefSeq:   NP_660571.1
- ProteinModelPortal:   O85290
- SMR:   O85290
- EnsemblBacteria:   EBBUCT00000000525
- GeneID:   1005422
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg223
- GeneTree:   EBGT00050000007779
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   BAPH198804:BUSG223-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30928; Mature: 30928

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYYDIIENAYLKKNEVNTKNIDIETKQTIHHVIELLNSGKIRVAEKKDNIWITNQWIK
CCHHHHHHHHHHCCCCCCCCCEECEEHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHHH
KSILLYMYLNQNNVFQGSFSNYYDKIPLKYENYNEKKFKEERIRVVPPATIRYGSFINSN
CEEEEEEEECCCCEEECCCHHHHHCCCEEECCCCHHHHHHCCEEECCCCEEEECCEECCC
TIIMPSYVNIGAYVDQGTMIDTWTTVGSCAQIGKNVHLSGGVGIGGVLEPLQNNPTIIED
EEEEECEEEECEEECCCEEEEEHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCEEEC
NCFIGARSEIVEGVIIEEGSVISMGVFIGQSTKIYNRETGEILYGRVPANSVVVSGSLPS
CEEECCHHHHHCEEEECCCCEEEEEEEECCCCEEECCCCCCEEEEECCCCCEEEECCCCC
KDRKYNLYAAVIVKRVDSKTLNKVEINQLLRDK
CCCCEEEEEEEEHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKYYDIIENAYLKKNEVNTKNIDIETKQTIHHVIELLNSGKIRVAEKKDNIWITNQWIK
CCHHHHHHHHHHCCCCCCCCCEECEEHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHHH
KSILLYMYLNQNNVFQGSFSNYYDKIPLKYENYNEKKFKEERIRVVPPATIRYGSFINSN
CEEEEEEEECCCCEEECCCHHHHHCCCEEECCCCHHHHHHCCEEECCCCEEEECCEECCC
TIIMPSYVNIGAYVDQGTMIDTWTTVGSCAQIGKNVHLSGGVGIGGVLEPLQNNPTIIED
EEEEECEEEECEEECCCEEEEEHHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCEEEC
NCFIGARSEIVEGVIIEEGSVISMGVFIGQSTKIYNRETGEILYGRVPANSVVVSGSLPS
CEEECCHHHHHCEEEECCCCEEEEEEEECCCCEEECCCCCCEEEEECCCCCEEEECCCCC
KDRKYNLYAAVIVKRVDSKTLNKVEINQLLRDK
CCCCEEEEEEEEHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438; 9688822