Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 213692927

GI number: 213692927

Start: 2286416

End: 2288932

Strand: Reverse

Name: ptrB [H]

Synonym: Blon_2071

Alternate gene names: 213692927

Gene position: 2288932-2286416 (Counterclockwise)

Preceding gene: 213692928

Following gene: 213692926

Centisome position: 80.8

GC content: 61.14

Gene sequence:

>2517_bases
ATGACTGACGAGAGCACAAACGCCGCGGCCGCGATGCCGCCTTATGCCAAACGCGAGCCGAAGCGCCGCGAATTCCACGG
TGACGTTTTCGAAGACGATTACGAGTGGATGCGAGACAAAGACTCCGATGATGTGCGCAGCTACGTAGCTGCCGAAAACC
AGTACTGCGAGCGTCGCATGGCGCATCTGGCGGATTTCCGGCATACGTTGTTTGAAGAGCTGAAATCGCATGTGGAAGAG
ACCGATATGTCGGTTCCCACGCGCGTCAATGATTACTGGTACTTCACCCGCACGCAGCAGGGCAAACAGTATGGCGTGCA
ATGCCGCATCCCCGTGTGCGATGCCGATGACTGGGACCCGCCGGTCGTGGATCCGCAAGGCGCGCCCGGCTCCATGCCCG
GTGAACAGGTCGTTTTTGATGCGAACAAGGAATCCGAGGGGCATGACTTCTTCCGGCTCGGCGGCTTGGATCTGAGCAAG
GACGGCCGTTGGATGCTGTACGGCGTGGATGTTGCGGGAGACGAACGATATGATTTCCGCATTCGCGACCTTGCCGGGCT
GGAGACCGGGGAGCCGGTCAGCGAACTGCCCGAACAGTTCACCGGCATTGGCAGCGCATGCTTCACGCCGGACGGCCAAT
GGGTGTTCTGGGTGGAATTGGACGATTCCTGGCGGCCGCTCGCCGTGTGGCGGCATCGTGTTGGCACGGCGGTCGAATCG
GATGTGTGCGTGTACCGAGAAACCGATGAACGGTTCTGGGTGGGCGTCGGCATCAGTTTTGATGAGCGCAATATCGTGAT
CGGCACCGGTTCCAAAACCACCACCGAAGTGCTGATGCTGCCGGTGGCCACGCCTGAAGGCGAATTCCAAGCCTTCATTC
CACGTCAGAACGATATTGAATATGATGTGAGCTTTGCCTGTTTTGAAGGCGTGGGGGAGAACGGTGCGGATGTGCCACTC
GCCGTGGTCTATCACAACGCCGCCAATCCGAATTTCGAAATCGACGTCATTGACATGCGTGGCCATGAGCCGCCGTACCG
GCTCGGCGAAGGCGTGTGCATTGCCGCCGGGTCGCCGTACGGCTGTGAACATGGTGAGCCGGATAAGCCGATTACCGAGG
CATACTTCAACGCCGCCAATCCGGCGATATTGCAGGGTGCCCACGGTCTGGGCATCGAAGGCATCGCGTTGCATCGCAAC
TTTGTGTCCCTGAGCTACCGTGCCGACGGCCAGCCGCACGTGGCATACATGACCAAGAGCGCGGCTGCCGCCGACTTCCT
GGCCGGACGGCCGTGGCGGTTTACGGAACTGCTGCCGCCTGCCCTGGAGGACGACTGGGACATGGTTGCCGCCGATCGCG
AAGGCTTCACCGGCGATCATGGCGAAATCTTGTGGACCGAAGATGAGGCCCCCACGGATCACACGTCATCTTCCGATGGT
GCCAGCGACGACCACCTGCCCGGTGAGACCCGGCGCTTGTACACCATCGGCGTCGGCGGCAACCCATCGTATGAGGCGCC
GCGCATGCGCTACTCGTTCGCCAGCTACACCCGCCCGGGCGAGCTGCACGAAATCGATCCCGCCACCGGTGAAGATACGC
TGCTGAAGCGAGCCACCGTGTTGGGCAACTTCAATCCACGCGATTACATGGAACGCCGTGTGTGGATTACCGCGCGCGAC
GGCGAACGCATTCCTGTTTCCCTCGTCTGGCACCGCGATTGCCCGGCGCAGGATTCGCCGATGTTCATTACCGGATATGG
TGCATACGAGATTTCCTCCGATCCGGGGTTCTCGGTCTCTCGTCTGAGCATGTTGGATCGCGGTGTGCTGTACGCCGTGC
CGCATATTCGTGGCGGCGGCGAAATGGGACGTGCCTGGTATGAACAGGGGCGCAGACTGAACAAGAAGCATTCCTTTGAG
GACTTCGTGGACGCCACACGCGCGCTGCAGAAGGCGCATTTGGCTGATGCTTGGCGCACCGTGGCCAACGGCGGATCCGC
TGGCGGCCTGCTGATGGGCGCGATTGCCAATATGGCGCCCGAATGCTACGCCGGTATTGAGGCGGATGTGCCGTTCGTGG
ACGCGTTGACCTCCATTCTTGACCCGGACTTGCCGTTGACCGTCACCGAATGGGACGAATGGGGAGACCCGTTGCATGAC
CCTGAGGTGTATCAGTACATGAAGTCGTACACGCCATACGAGAATGTGCCGGTCACCGTGCTCGAGGGCGGCGACGACGA
GGCTGCCGGTGGCGGCAGTGCTGATGGGGCTGCCACCGGCGCGCTCGCCGCCGCGCAATTCCCGAGAATCTTCATTACCA
CCTCGATGAACGACACCCGCGTGCTGTACGTCGAGCCGCTCAAATGGCTGGCCCGTCTGCAGTCCGCCGGCGTGGACGCG
GTGGCCAAGATTGAGGTCGAGGCCGGTCACGGCGGTCTATCCGGGCGTTACAAGCAATGGGAAGAGGTTTCCTATGAGAA
CGCTTGGTGCATGGATGTGATGGGGCTCGCTCATTAG

Upstream 100 bases:

>100_bases
GAAGACCATGCTGCCGTATCTGAAGACGGTGTTGCGATAAGCGCGGCGTGATGAACGCCGAATGCGTCCCGGTGTGGTGC
CTCGCCTATAATCGCGTGGT

Downstream 100 bases:

>100_bases
GTCATTCTGTCGTTCATTAGGTCGGTGTCCTCTTCTATGTGAGACTGAAATGCCGCCATTTCAGTCCCTGAAATGAACCC
ACACCGACCTAATGAACACT

Product: Oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 838; Mature: 837

Protein sequence:

>838_residues
MTDESTNAAAAMPPYAKREPKRREFHGDVFEDDYEWMRDKDSDDVRSYVAAENQYCERRMAHLADFRHTLFEELKSHVEE
TDMSVPTRVNDYWYFTRTQQGKQYGVQCRIPVCDADDWDPPVVDPQGAPGSMPGEQVVFDANKESEGHDFFRLGGLDLSK
DGRWMLYGVDVAGDERYDFRIRDLAGLETGEPVSELPEQFTGIGSACFTPDGQWVFWVELDDSWRPLAVWRHRVGTAVES
DVCVYRETDERFWVGVGISFDERNIVIGTGSKTTTEVLMLPVATPEGEFQAFIPRQNDIEYDVSFACFEGVGENGADVPL
AVVYHNAANPNFEIDVIDMRGHEPPYRLGEGVCIAAGSPYGCEHGEPDKPITEAYFNAANPAILQGAHGLGIEGIALHRN
FVSLSYRADGQPHVAYMTKSAAAADFLAGRPWRFTELLPPALEDDWDMVAADREGFTGDHGEILWTEDEAPTDHTSSSDG
ASDDHLPGETRRLYTIGVGGNPSYEAPRMRYSFASYTRPGELHEIDPATGEDTLLKRATVLGNFNPRDYMERRVWITARD
GERIPVSLVWHRDCPAQDSPMFITGYGAYEISSDPGFSVSRLSMLDRGVLYAVPHIRGGGEMGRAWYEQGRRLNKKHSFE
DFVDATRALQKAHLADAWRTVANGGSAGGLLMGAIANMAPECYAGIEADVPFVDALTSILDPDLPLTVTEWDEWGDPLHD
PEVYQYMKSYTPYENVPVTVLEGGDDEAAGGGSADGAATGALAAAQFPRIFITTSMNDTRVLYVEPLKWLARLQSAGVDA
VAKIEVEAGHGGLSGRYKQWEEVSYENAWCMDVMGLAH

Sequences:

>Translated_838_residues
MTDESTNAAAAMPPYAKREPKRREFHGDVFEDDYEWMRDKDSDDVRSYVAAENQYCERRMAHLADFRHTLFEELKSHVEE
TDMSVPTRVNDYWYFTRTQQGKQYGVQCRIPVCDADDWDPPVVDPQGAPGSMPGEQVVFDANKESEGHDFFRLGGLDLSK
DGRWMLYGVDVAGDERYDFRIRDLAGLETGEPVSELPEQFTGIGSACFTPDGQWVFWVELDDSWRPLAVWRHRVGTAVES
DVCVYRETDERFWVGVGISFDERNIVIGTGSKTTTEVLMLPVATPEGEFQAFIPRQNDIEYDVSFACFEGVGENGADVPL
AVVYHNAANPNFEIDVIDMRGHEPPYRLGEGVCIAAGSPYGCEHGEPDKPITEAYFNAANPAILQGAHGLGIEGIALHRN
FVSLSYRADGQPHVAYMTKSAAAADFLAGRPWRFTELLPPALEDDWDMVAADREGFTGDHGEILWTEDEAPTDHTSSSDG
ASDDHLPGETRRLYTIGVGGNPSYEAPRMRYSFASYTRPGELHEIDPATGEDTLLKRATVLGNFNPRDYMERRVWITARD
GERIPVSLVWHRDCPAQDSPMFITGYGAYEISSDPGFSVSRLSMLDRGVLYAVPHIRGGGEMGRAWYEQGRRLNKKHSFE
DFVDATRALQKAHLADAWRTVANGGSAGGLLMGAIANMAPECYAGIEADVPFVDALTSILDPDLPLTVTEWDEWGDPLHD
PEVYQYMKSYTPYENVPVTVLEGGDDEAAGGGSADGAATGALAAAQFPRIFITTSMNDTRVLYVEPLKWLARLQSAGVDA
VAKIEVEAGHGGLSGRYKQWEEVSYENAWCMDVMGLAH
>Mature_837_residues
TDESTNAAAAMPPYAKREPKRREFHGDVFEDDYEWMRDKDSDDVRSYVAAENQYCERRMAHLADFRHTLFEELKSHVEET
DMSVPTRVNDYWYFTRTQQGKQYGVQCRIPVCDADDWDPPVVDPQGAPGSMPGEQVVFDANKESEGHDFFRLGGLDLSKD
GRWMLYGVDVAGDERYDFRIRDLAGLETGEPVSELPEQFTGIGSACFTPDGQWVFWVELDDSWRPLAVWRHRVGTAVESD
VCVYRETDERFWVGVGISFDERNIVIGTGSKTTTEVLMLPVATPEGEFQAFIPRQNDIEYDVSFACFEGVGENGADVPLA
VVYHNAANPNFEIDVIDMRGHEPPYRLGEGVCIAAGSPYGCEHGEPDKPITEAYFNAANPAILQGAHGLGIEGIALHRNF
VSLSYRADGQPHVAYMTKSAAAADFLAGRPWRFTELLPPALEDDWDMVAADREGFTGDHGEILWTEDEAPTDHTSSSDGA
SDDHLPGETRRLYTIGVGGNPSYEAPRMRYSFASYTRPGELHEIDPATGEDTLLKRATVLGNFNPRDYMERRVWITARDG
ERIPVSLVWHRDCPAQDSPMFITGYGAYEISSDPGFSVSRLSMLDRGVLYAVPHIRGGGEMGRAWYEQGRRLNKKHSFED
FVDATRALQKAHLADAWRTVANGGSAGGLLMGAIANMAPECYAGIEADVPFVDALTSILDPDLPLTVTEWDEWGDPLHDP
EVYQYMKSYTPYENVPVTVLEGGDDEAAGGGSADGAATGALAAAQFPRIFITTSMNDTRVLYVEPLKWLARLQSAGVDAV
AKIEVEAGHGGLSGRYKQWEEVSYENAWCMDVMGLAH

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=368, Percent_Identity=28.5326086956522, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI108860686, Length=303, Percent_Identity=29.3729372937294, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI284172420, Length=303, Percent_Identity=29.3729372937294, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI284172413, Length=303, Percent_Identity=29.3729372937294, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI70778815, Length=303, Percent_Identity=29.3729372937294, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI284172438, Length=260, Percent_Identity=29.2307692307692, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI284172431, Length=260, Percent_Identity=29.2307692307692, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI108860692, Length=256, Percent_Identity=29.296875, Blast_Score=110, Evalue=4e-24,
Organism=Escherichia coli, GI1788150, Length=342, Percent_Identity=42.1052631578947, Blast_Score=271, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24583414, Length=341, Percent_Identity=27.5659824046921, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI221510989, Length=331, Percent_Identity=26.8882175226586, Blast_Score=103, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 93009; Mature: 92878

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDESTNAAAAMPPYAKREPKRREFHGDVFEDDYEWMRDKDSDDVRSYVAAENQYCERRM
CCCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
AHLADFRHTLFEELKSHVEETDMSVPTRVNDYWYFTRTQQGKQYGVQCRIPVCDADDWDP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCCCEEEEEECCCCCCCC
PVVDPQGAPGSMPGEQVVFDANKESEGHDFFRLGGLDLSKDGRWMLYGVDVAGDERYDFR
CCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCEEECCCCCEEEEEEEECCCCCEEEE
IRDLAGLETGEPVSELPEQFTGIGSACFTPDGQWVFWVELDDSWRPLAVWRHRVGTAVES
EEECCCCCCCCCHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCC
DVCVYRETDERFWVGVGISFDERNIVIGTGSKTTTEVLMLPVATPEGEFQAFIPRQNDIE
CEEEEEECCCEEEEEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCCCC
YDVSFACFEGVGENGADVPLAVVYHNAANPNFEIDVIDMRGHEPPYRLGEGVCIAAGSPY
EEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHCCCEEEECCCCC
GCEHGEPDKPITEAYFNAANPAILQGAHGLGIEGIALHRNFVSLSYRADGQPHVAYMTKS
CCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEECC
AAAADFLAGRPWRFTELLPPALEDDWDMVAADREGFTGDHGEILWTEDEAPTDHTSSSDG
HHHHHHHCCCCEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCC
ASDDHLPGETRRLYTIGVGGNPSYEAPRMRYSFASYTRPGELHEIDPATGEDTLLKRATV
CCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEHHHCCCCCCCEECCCCCCCHHHHHHHHH
LGNFNPRDYMERRVWITARDGERIPVSLVWHRDCPAQDSPMFITGYGAYEISSDPGFSVS
HCCCCHHHHHCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCEEEECCCCCCCHH
RLSMLDRGVLYAVPHIRGGGEMGRAWYEQGRRLNKKHSFEDFVDATRALQKAHLADAWRT
HHHHHHCCEEEEECCCCCCHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VANGGSAGGLLMGAIANMAPECYAGIEADVPFVDALTSILDPDLPLTVTEWDEWGDPLHD
HHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCHHCCCCCCC
PEVYQYMKSYTPYENVPVTVLEGGDDEAAGGGSADGAATGALAAAQFPRIFITTSMNDTR
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCE
VLYVEPLKWLARLQSAGVDAVAKIEVEAGHGGLSGRYKQWEEVSYENAWCMDVMGLAH
EEEECHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
TDESTNAAAAMPPYAKREPKRREFHGDVFEDDYEWMRDKDSDDVRSYVAAENQYCERRM
CCCCCCCCCCCCCHHHCCCCHHHHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
AHLADFRHTLFEELKSHVEETDMSVPTRVNDYWYFTRTQQGKQYGVQCRIPVCDADDWDP
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEECCCCCCCCCEEEEEECCCCCCCC
PVVDPQGAPGSMPGEQVVFDANKESEGHDFFRLGGLDLSKDGRWMLYGVDVAGDERYDFR
CCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCEEECCCCCEEEEEEEECCCCCEEEE
IRDLAGLETGEPVSELPEQFTGIGSACFTPDGQWVFWVELDDSWRPLAVWRHRVGTAVES
EEECCCCCCCCCHHHHHHHHHCCCCEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCCC
DVCVYRETDERFWVGVGISFDERNIVIGTGSKTTTEVLMLPVATPEGEFQAFIPRQNDIE
CEEEEEECCCEEEEEEEEEECCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCCCCCC
YDVSFACFEGVGENGADVPLAVVYHNAANPNFEIDVIDMRGHEPPYRLGEGVCIAAGSPY
EEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHCCCEEEECCCCC
GCEHGEPDKPITEAYFNAANPAILQGAHGLGIEGIALHRNFVSLSYRADGQPHVAYMTKS
CCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEEEEEEECCCCCEEEEEECC
AAAADFLAGRPWRFTELLPPALEDDWDMVAADREGFTGDHGEILWTEDEAPTDHTSSSDG
HHHHHHHCCCCEEHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCC
ASDDHLPGETRRLYTIGVGGNPSYEAPRMRYSFASYTRPGELHEIDPATGEDTLLKRATV
CCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEHHHCCCCCCCEECCCCCCCHHHHHHHHH
LGNFNPRDYMERRVWITARDGERIPVSLVWHRDCPAQDSPMFITGYGAYEISSDPGFSVS
HCCCCHHHHHCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEEEECCEEEECCCCCCCHH
RLSMLDRGVLYAVPHIRGGGEMGRAWYEQGRRLNKKHSFEDFVDATRALQKAHLADAWRT
HHHHHHCCEEEEECCCCCCHHHHHHHHHHCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VANGGSAGGLLMGAIANMAPECYAGIEADVPFVDALTSILDPDLPLTVTEWDEWGDPLHD
HHCCCCCCHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEEECCHHCCCCCCC
PEVYQYMKSYTPYENVPVTVLEGGDDEAAGGGSADGAATGALAAAQFPRIFITTSMNDTR
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCE
VLYVEPLKWLARLQSAGVDAVAKIEVEAGHGGLSGRYKQWEEVSYENAWCMDVMGLAH
EEEECHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]