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The map label for this gene is glnA1 [H]

Identifier: 213692759

GI number: 213692759

Start: 2065228

End: 2066664

Strand: Direct

Name: glnA1 [H]

Synonym: Blon_1893

Alternate gene names: 213692759

Gene position: 2065228-2066664 (Clockwise)

Preceding gene: 213692758

Following gene: 213692768

Centisome position: 72.91

GC content: 62.14

Gene sequence:

>1437_bases
GTGACCGAACTCAAGTCCAAGGAAGACGTCGAGGCCCTTATCAACAAGGAAGGCATCGAGTATGTCTCCGTCCGTTTCAC
CGATCTTATCGGCGTTCAGCAGCACTTCACCGTGCCGGCTAGCGAATTCCTGAAGGACGCTTTCACCGACGGCATGCCGT
TCGATGGTTCCTCCGTTCAGGGCTTCCAGGCCATCAACGAGTCCGACATGAAGCTGGTCCCGGACGTTGAGACCTCTTTC
GTTGACCCGTTCCGCAAGCACAAGACCCTTGACGTGGCCTTCTCCATCGTCGACCCGCTGACCGACGAGCCGTACTCCCG
CGACCCGCGTCAGGTCGCCGGCAAGGCCGAGGCCTACCTGAAGTCCACCGGCATCGCCGACACCGCATCCTTCGCCCCTG
AGGCCGAGTTCTTCATCTTCGACAAGGTGCGTTTCGAGAACTCCATGCAGCGCTCCTTCTACGAGGTCGACTCCATCGAA
GCTCCGTGGAACTCCGGCGTTGACTCCGAAGAGGACGGCACCCCGAACATCGGTTTCAAGAATCGCGTCAAGAAGGGCTA
CTTCCCGGTTCCGCCGATTGACCACACCCAGGATCTGCGCGACGATATGGTCGCCAACCTGCAGAAGGTCGGTCTGATCC
TCGAGCGTTCCCACCACGAGGTCGCCGGCGCTGGCCAGCAGGAGATCAACTACCGCTTCAACACCCTGCAGCACGCAGGC
GATGACCTGATGAAGTACAAGTACGTCGTCCACGAGACCGCCGCTCTGGCTGGCAAGGCTGCGACCTTCATGCCGAAGCC
GATCGCCGACGACAACGGCACTGGTATGCACTGCCACCAGTCCCTGTGGAAGGACGGCAAGCCGCTGTTCTACGACGAGA
AGGGCTACGCTGGTCTGTCCGATCTGGCTCGCTGGTACATCGGCGGTCTGATCAAGCACTCCTCCTCCGTGCTGGCCTTC
ACCAACCCGTCCCTGAACTCCTACCACCGTCTGGTCCCGGGCTTCGAGGCTCCGGTCAACCTGGTGTACTCCGCTCGTAA
CCGTTCTGCCGCCATCCGTATTCCGCTGGCCGGCACCTCCCCGGCTGCCAAGCGCATCGAGTTCCGCGCTCCGGATCCGT
CCTGCAACCCGTTCCTGGCCTTCTCCGCTCAGCTGATGGCTGGCCTGGACGGCATCCTGAACCACATCGAGCCTCCGGAG
CCGGTCGACAAGGACCTCTACGAGCTGCCGCCGGAAGAGCACGCTGGCATCAAGCAGGTGCCAAGCTCCCTGGCCGAGGC
TATGGACGCCCTGGAAGAGGACCACGACTTCCTCACCGCCGGCGACGTGTTCACCGACGACCTGATCGAGACCTGGATTG
GCCTCAAGCGCGACGAGATCGACCAGGCTCGCCTGGCCCCGACCCCGCTCGAGTACGAGCTCTACTTCCACATCTGA

Upstream 100 bases:

>100_bases
GCCACAGTCACGAAACATTCTCGTAACCCAAGTTTCGAGCCGGCGAAACGCGCTATTTTACGATATATACCGTTATATCT
CATACGAAAGGAGCGGTCCC

Downstream 100 bases:

>100_bases
GTTTGAGAGCTTAGCAACGTTGGGATTTCGCCATTGCTCTTCTCTTGTGGGAGTCTAATGGGAGTCATTCAGCGTAACTA
GAAAGAACCTCGTGAAATTC

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase 1 [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTELKSKEDVEALINKEGIEYVSVRFTDLIGVQQHFTVPASEFLKDAFTDGMPFDGSSVQGFQAINESDMKLVPDVETSF
VDPFRKHKTLDVAFSIVDPLTDEPYSRDPRQVAGKAEAYLKSTGIADTASFAPEAEFFIFDKVRFENSMQRSFYEVDSIE
APWNSGVDSEEDGTPNIGFKNRVKKGYFPVPPIDHTQDLRDDMVANLQKVGLILERSHHEVAGAGQQEINYRFNTLQHAG
DDLMKYKYVVHETAALAGKAATFMPKPIADDNGTGMHCHQSLWKDGKPLFYDEKGYAGLSDLARWYIGGLIKHSSSVLAF
TNPSLNSYHRLVPGFEAPVNLVYSARNRSAAIRIPLAGTSPAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGILNHIEPPE
PVDKDLYELPPEEHAGIKQVPSSLAEAMDALEEDHDFLTAGDVFTDDLIETWIGLKRDEIDQARLAPTPLEYELYFHI

Sequences:

>Translated_478_residues
MTELKSKEDVEALINKEGIEYVSVRFTDLIGVQQHFTVPASEFLKDAFTDGMPFDGSSVQGFQAINESDMKLVPDVETSF
VDPFRKHKTLDVAFSIVDPLTDEPYSRDPRQVAGKAEAYLKSTGIADTASFAPEAEFFIFDKVRFENSMQRSFYEVDSIE
APWNSGVDSEEDGTPNIGFKNRVKKGYFPVPPIDHTQDLRDDMVANLQKVGLILERSHHEVAGAGQQEINYRFNTLQHAG
DDLMKYKYVVHETAALAGKAATFMPKPIADDNGTGMHCHQSLWKDGKPLFYDEKGYAGLSDLARWYIGGLIKHSSSVLAF
TNPSLNSYHRLVPGFEAPVNLVYSARNRSAAIRIPLAGTSPAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGILNHIEPPE
PVDKDLYELPPEEHAGIKQVPSSLAEAMDALEEDHDFLTAGDVFTDDLIETWIGLKRDEIDQARLAPTPLEYELYFHI
>Mature_477_residues
TELKSKEDVEALINKEGIEYVSVRFTDLIGVQQHFTVPASEFLKDAFTDGMPFDGSSVQGFQAINESDMKLVPDVETSFV
DPFRKHKTLDVAFSIVDPLTDEPYSRDPRQVAGKAEAYLKSTGIADTASFAPEAEFFIFDKVRFENSMQRSFYEVDSIEA
PWNSGVDSEEDGTPNIGFKNRVKKGYFPVPPIDHTQDLRDDMVANLQKVGLILERSHHEVAGAGQQEINYRFNTLQHAGD
DLMKYKYVVHETAALAGKAATFMPKPIADDNGTGMHCHQSLWKDGKPLFYDEKGYAGLSDLARWYIGGLIKHSSSVLAFT
NPSLNSYHRLVPGFEAPVNLVYSARNRSAAIRIPLAGTSPAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGILNHIEPPEP
VDKDLYELPPEEHAGIKQVPSSLAEAMDALEEDHDFLTAGDVFTDDLIETWIGLKRDEIDQARLAPTPLEYELYFHI

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=489, Percent_Identity=23.721881390593, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1790301, Length=473, Percent_Identity=52.431289640592, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI87081870, Length=404, Percent_Identity=26.980198019802, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53256; Mature: 53125

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELKSKEDVEALINKEGIEYVSVRFTDLIGVQQHFTVPASEFLKDAFTDGMPFDGSSVQ
CCCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCHHHCCCCHHHHHHHHHHCCCCCCCCCCC
GFQAINESDMKLVPDVETSFVDPFRKHKTLDVAFSIVDPLTDEPYSRDPRQVAGKAEAYL
HHHHCCCCCCEECCCCHHHHHCHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KSTGIADTASFAPEAEFFIFDKVRFENSMQRSFYEVDSIEAPWNSGVDSEEDGTPNIGFK
HHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
NRVKKGYFPVPPIDHTQDLRDDMVANLQKVGLILERSHHEVAGAGQQEINYRFNTLQHAG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCC
DDLMKYKYVVHETAALAGKAATFMPKPIADDNGTGMHCHQSLWKDGKPLFYDEKGYAGLS
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCHH
DLARWYIGGLIKHSSSVLAFTNPSLNSYHRLVPGFEAPVNLVYSARNRSAAIRIPLAGTS
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEECCCC
PAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGILNHIEPPEPVDKDLYELPPEEHAGIKQV
CHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHCCCHHHH
PSSLAEAMDALEEDHDFLTAGDVFTDDLIETWIGLKRDEIDQARLAPTPLEYELYFHI
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCHHCCCHHHCCCCCCEEEEEEEC
>Mature Secondary Structure 
TELKSKEDVEALINKEGIEYVSVRFTDLIGVQQHFTVPASEFLKDAFTDGMPFDGSSVQ
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHCCHHHCCCCHHHHHHHHHHCCCCCCCCCCC
GFQAINESDMKLVPDVETSFVDPFRKHKTLDVAFSIVDPLTDEPYSRDPRQVAGKAEAYL
HHHHCCCCCCEECCCCHHHHHCHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KSTGIADTASFAPEAEFFIFDKVRFENSMQRSFYEVDSIEAPWNSGVDSEEDGTPNIGFK
HHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
NRVKKGYFPVPPIDHTQDLRDDMVANLQKVGLILERSHHEVAGAGQQEINYRFNTLQHAG
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCC
DDLMKYKYVVHETAALAGKAATFMPKPIADDNGTGMHCHQSLWKDGKPLFYDEKGYAGLS
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCHH
DLARWYIGGLIKHSSSVLAFTNPSLNSYHRLVPGFEAPVNLVYSARNRSAAIRIPLAGTS
HHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHEEECCCCCEEEEEEECCCC
PAAKRIEFRAPDPSCNPFLAFSAQLMAGLDGILNHIEPPEPVDKDLYELPPEEHAGIKQV
CHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHCCCHHHH
PSSLAEAMDALEEDHDFLTAGDVFTDDLIETWIGLKRDEIDQARLAPTPLEYELYFHI
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCHHCCCHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]