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The map label for this gene is arcB

Identifier: 213692743

GI number: 213692743

Start: 2045924

End: 2046889

Strand: Reverse

Name: arcB

Synonym: Blon_1877

Alternate gene names: 213692743

Gene position: 2046889-2045924 (Counterclockwise)

Preceding gene: 213692744

Following gene: 213692742

Centisome position: 72.26

GC content: 64.18

Gene sequence:

>966_bases
ATGACCCCAGAACTTCGCCACATGTTGCGAGATGACGACCTCAACCATGAGGAGCAGAAGCAGGTGCTCGAACTTGCCAT
CAAGTTCCACCATGACCGCTTCTACAAGCAGCCGTTCGCCGGTCCGCAGGCCGTCGCCGTACTGTTCGACAAGCCATCCA
CCCGCACCCGTTCCAGCTTCTCCATCGGCGTTGCCGAGCTTGGCGGCTACCCGCTGGTCATCGACAAGTCCGGCTCCCAG
CTGGGCCGTGGCGAGCCCGTGGCCGATACCGCTCGTGTGCTCGACCGCATGGCTTACGGCGTGGTGTGGCGCACCTTCGG
CCAGGACCGCGTCGAAGAAATGGCCAAGTACTCCACCCATCCGGTGGTCAACGCCCTGACCGATGACTTCCATCCCTGCC
AGATTCTCGCCGACTTCCAGACCATCGCCGAGCACCGAGGCGGCGTCGACAACCTGAAGAACCAGACCATCGCCTACCTC
GGTGACGCGGCCAACAACATGGCCAACTCCTACCTGCTCGGCGGTGCCGTGGCCGGCATGGACGTGCGCGTGGCCGGCCC
CCACGGCTACCTGCCCCGCCCGGACATCGTGGCCGACGCCAAGCGCGTCGCGGCCGAGACCGGCGGCTCCATCCTGGTCA
CCACCGATGCCAAGGAAGCGGTGAAGGACGCCGACTGCGTGTTCACCGACACCTGGGTCTCCATGGGCGAGGAGGCCGAA
TACGCCATCCGTTCCAAGCCGTTCTGGGATTACCAGGTCAACACCGAACTTATGGCATTGGCCAAGCCGGATGCGCTCTT
CCAGCACTGCCTGCCCGCCTACCGCGGCAAGGAAGTCACCGCTGAAGTGATCGATGGCCCGCAGTCCGTGGTATGGGACG
AGGCCGAGAACCGTCTGCACGCACAGAAAGCGTTGCTGACTTGGTTGACCGGCAAGGCCCGTGGAGACGAAAGCCTGCTC
GCATGA

Upstream 100 bases:

>100_bases
GTGGATCAGGCACTTGCCATCCTCAAGGATGTGCCTACGGACCTGCCCGACGACTGATTTCTCGCCGTCACTGCCGACCC
ACCGATCCAAGGAGATCATC

Downstream 100 bases:

>100_bases
GTGAAACCGGTCCGTCCCTGCAGCGCCCTGCCACCAGGGCGGCGCGGCTGAGTGCCATAGAACAGGCGCTCGCCACGCAT
ATCATCACCTCGCAATCACA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTPELRHMLRDDDLNHEEQKQVLELAIKFHHDRFYKQPFAGPQAVAVLFDKPSTRTRSSFSIGVAELGGYPLVIDKSGSQ
LGRGEPVADTARVLDRMAYGVVWRTFGQDRVEEMAKYSTHPVVNALTDDFHPCQILADFQTIAEHRGGVDNLKNQTIAYL
GDAANNMANSYLLGGAVAGMDVRVAGPHGYLPRPDIVADAKRVAAETGGSILVTTDAKEAVKDADCVFTDTWVSMGEEAE
YAIRSKPFWDYQVNTELMALAKPDALFQHCLPAYRGKEVTAEVIDGPQSVVWDEAENRLHAQKALLTWLTGKARGDESLL
A

Sequences:

>Translated_321_residues
MTPELRHMLRDDDLNHEEQKQVLELAIKFHHDRFYKQPFAGPQAVAVLFDKPSTRTRSSFSIGVAELGGYPLVIDKSGSQ
LGRGEPVADTARVLDRMAYGVVWRTFGQDRVEEMAKYSTHPVVNALTDDFHPCQILADFQTIAEHRGGVDNLKNQTIAYL
GDAANNMANSYLLGGAVAGMDVRVAGPHGYLPRPDIVADAKRVAAETGGSILVTTDAKEAVKDADCVFTDTWVSMGEEAE
YAIRSKPFWDYQVNTELMALAKPDALFQHCLPAYRGKEVTAEVIDGPQSVVWDEAENRLHAQKALLTWLTGKARGDESLL
A
>Mature_320_residues
TPELRHMLRDDDLNHEEQKQVLELAIKFHHDRFYKQPFAGPQAVAVLFDKPSTRTRSSFSIGVAELGGYPLVIDKSGSQL
GRGEPVADTARVLDRMAYGVVWRTFGQDRVEEMAKYSTHPVVNALTDDFHPCQILADFQTIAEHRGGVDNLKNQTIAYLG
DAANNMANSYLLGGAVAGMDVRVAGPHGYLPRPDIVADAKRVAAETGGSILVTTDAKEAVKDADCVFTDTWVSMGEEAEY
AIRSKPFWDYQVNTELMALAKPDALFQHCLPAYRGKEVTAEVIDGPQSVVWDEAENRLHAQKALLTWLTGKARGDESLLA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=296, Percent_Identity=37.8378378378378, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI18105007, Length=274, Percent_Identity=28.4671532846715, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1790703, Length=323, Percent_Identity=39.0092879256966, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1786469, Length=330, Percent_Identity=39.0909090909091, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI48994908, Length=330, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193204318, Length=318, Percent_Identity=25.1572327044025, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=324, Percent_Identity=33.3333333333333, Blast_Score=170, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24642586, Length=313, Percent_Identity=26.8370607028754, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): OTC_BIFLI (B7GTP2)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002323329.1
- GeneID:   7055309
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_1877
- HOGENOM:   HBG579429
- ProtClustDB:   PRK00779
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 35387; Mature: 35256

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 104-104 BINDING 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPELRHMLRDDDLNHEEQKQVLELAIKFHHDRFYKQPFAGPQAVAVLFDKPSTRTRSSF
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
SIGVAELGGYPLVIDKSGSQLGRGEPVADTARVLDRMAYGVVWRTFGQDRVEEMAKYSTH
EEEHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PVVNALTDDFHPCQILADFQTIAEHRGGVDNLKNQTIAYLGDAANNMANSYLLGGAVAGM
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEECHHHHHHHHHHHHCCEEECC
DVRVAGPHGYLPRPDIVADAKRVAAETGGSILVTTDAKEAVKDADCVFTDTWVSMGEEAE
EEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCEEEHHHHHCCCCHH
YAIRSKPFWDYQVNTELMALAKPDALFQHCLPAYRGKEVTAEVIDGPQSVVWDEAENRLH
HHHHCCCCEEEEECCEEEEECCCHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHHH
AQKALLTWLTGKARGDESLLA
HHHHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
TPELRHMLRDDDLNHEEQKQVLELAIKFHHDRFYKQPFAGPQAVAVLFDKPSTRTRSSF
CHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
SIGVAELGGYPLVIDKSGSQLGRGEPVADTARVLDRMAYGVVWRTFGQDRVEEMAKYSTH
EEEHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PVVNALTDDFHPCQILADFQTIAEHRGGVDNLKNQTIAYLGDAANNMANSYLLGGAVAGM
CHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCCEEEECHHHHHHHHHHHHCCEEECC
DVRVAGPHGYLPRPDIVADAKRVAAETGGSILVTTDAKEAVKDADCVFTDTWVSMGEEAE
EEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCEEEHHHHHCCCCHH
YAIRSKPFWDYQVNTELMALAKPDALFQHCLPAYRGKEVTAEVIDGPQSVVWDEAENRLH
HHHHCCCCEEEEECCEEEEECCCHHHHHHHHHHHCCCCEEHHHHCCCHHHHHHHHHHHHH
AQKALLTWLTGKARGDESLLA
HHHHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA