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The map label for this gene is argD [H]

Identifier: 213692744

GI number: 213692744

Start: 2046933

End: 2048228

Strand: Reverse

Name: argD [H]

Synonym: Blon_1878

Alternate gene names: 213692744

Gene position: 2048228-2046933 (Counterclockwise)

Preceding gene: 213692745

Following gene: 213692743

Centisome position: 72.31

GC content: 59.34

Gene sequence:

>1296_bases
ATGGCTACTGAGCATGAGGAAAAACTAGGTACGGAAGACAGCAAGTGGCTGGGAGAGTACTCTCAGGTCCACATGAATGT
GTTCGGTACGCCGTTGCGCGTCATGGATCACGGCCAAGGTGCCCACATCTGGGATGTTGACGGTAACGAATACCTCGATT
TCCTGGCAGGCATCGCCGTCAATTCCCTCGGATACGCCCACCCCAAGTGGGTCAAGGCGGTTGCCGATCAGGCTGCCAAG
GTGGCTCATATCAGCAACTATTTCGCGTCCGAGCCGCAAATTGAATTGGCGTCCAAACTGGTCAAGCTGGCTGGTGCACC
TGAAGGCTCCAAAGTCTACTTCGGCAACTCCGGTGCTGAAGGCAATGAAGCTGCCCTCAAGCTCGCCAAGCTGTATGGCC
GCACCTTGCCTGATGCCCTGCCTTCCATCGGCGGCAAGCCCGCACGCATTCTCGCAATGACTCACGGCTTCCATGGCCGT
ACGATGGGTGCGCTGTCCGCCACATGGAAACCCGGTATCCGCAAGCCGTATGATCCGCTGGTGCCGAACATCGAATTCGT
GCGCGCCGGCGACAAGGTCGCCCTGCACGACGCTTTTGCACAGACCGGTCTCGGTCGCTATGGCAAGGGTCCGGTGGCTG
CTGTGATTCTGGAACTTATCCAAGGCGAAGCCGGCGTGCAGCCGTTGGGCGCCGATTACGTCAAGTTCGTGCGTGAACTG
TGCGATATCAACCACGCGCTGCTCATCATCGATGAAGTACAGACCGGTATCGGACGTACCGGCAAGTGGTTCGCATTCCA
GCGTGACGATCTGTCCGGCGGCGTGACGCCGGATATGGTGACTTTCGCCAAGGGTGTGGCAGGCGGATTCCCGATGGGCG
GCATGATCGCTTTTGGTGAGAAACTTGCGGCTCTGTTCACTCCTGGTTCCCACGGCTCCACCTTTGCCGGCAATCCGCTG
GGTGCGGCTGCGGGACTCGCCACTCTTGACGTGATTGAAGACGAGAATCTGGTGACCAACGCCGAAGCTCGCGGCAAACA
GCTGCGCGATGGCATTATGGCCACCGGTAATCCGCTGTTCGTTTCCGTACGCGGCCGTGGTTTGCTGGACGCCGTCGAGC
TCAAGCATCCCTGCTCCCACGCGGTGATGAACTACTGCCTCGAACACGGGCTCATCGTCAACGCGGTGGCTCCCAATGCG
CTGCGTTTCGCACCGCCGCTGATTGTAACCGCTCAAGACGTGGATCAGGCACTTGCCATCCTCAAGGATGTGCCTACGGA
CCTGCCCGACGACTGA

Upstream 100 bases:

>100_bases
GACGGGCGCAAGCCGCATTCGATTTTGAATGAGATATTCACCTCCGCAGGCATCGGTACCATGGTTATGCCCGATGAAGG
ACTGGAAATGAGGAGCTCTT

Downstream 100 bases:

>100_bases
TTTCTCGCCGTCACTGCCGACCCACCGATCCAAGGAGATCATCATGACCCCAGAACTTCGCCACATGTTGCGAGATGACG
ACCTCAACCATGAGGAGCAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MATEHEEKLGTEDSKWLGEYSQVHMNVFGTPLRVMDHGQGAHIWDVDGNEYLDFLAGIAVNSLGYAHPKWVKAVADQAAK
VAHISNYFASEPQIELASKLVKLAGAPEGSKVYFGNSGAEGNEAALKLAKLYGRTLPDALPSIGGKPARILAMTHGFHGR
TMGALSATWKPGIRKPYDPLVPNIEFVRAGDKVALHDAFAQTGLGRYGKGPVAAVILELIQGEAGVQPLGADYVKFVREL
CDINHALLIIDEVQTGIGRTGKWFAFQRDDLSGGVTPDMVTFAKGVAGGFPMGGMIAFGEKLAALFTPGSHGSTFAGNPL
GAAAGLATLDVIEDENLVTNAEARGKQLRDGIMATGNPLFVSVRGRGLLDAVELKHPCSHAVMNYCLEHGLIVNAVAPNA
LRFAPPLIVTAQDVDQALAILKDVPTDLPDD

Sequences:

>Translated_431_residues
MATEHEEKLGTEDSKWLGEYSQVHMNVFGTPLRVMDHGQGAHIWDVDGNEYLDFLAGIAVNSLGYAHPKWVKAVADQAAK
VAHISNYFASEPQIELASKLVKLAGAPEGSKVYFGNSGAEGNEAALKLAKLYGRTLPDALPSIGGKPARILAMTHGFHGR
TMGALSATWKPGIRKPYDPLVPNIEFVRAGDKVALHDAFAQTGLGRYGKGPVAAVILELIQGEAGVQPLGADYVKFVREL
CDINHALLIIDEVQTGIGRTGKWFAFQRDDLSGGVTPDMVTFAKGVAGGFPMGGMIAFGEKLAALFTPGSHGSTFAGNPL
GAAAGLATLDVIEDENLVTNAEARGKQLRDGIMATGNPLFVSVRGRGLLDAVELKHPCSHAVMNYCLEHGLIVNAVAPNA
LRFAPPLIVTAQDVDQALAILKDVPTDLPDD
>Mature_430_residues
ATEHEEKLGTEDSKWLGEYSQVHMNVFGTPLRVMDHGQGAHIWDVDGNEYLDFLAGIAVNSLGYAHPKWVKAVADQAAKV
AHISNYFASEPQIELASKLVKLAGAPEGSKVYFGNSGAEGNEAALKLAKLYGRTLPDALPSIGGKPARILAMTHGFHGRT
MGALSATWKPGIRKPYDPLVPNIEFVRAGDKVALHDAFAQTGLGRYGKGPVAAVILELIQGEAGVQPLGADYVKFVRELC
DINHALLIIDEVQTGIGRTGKWFAFQRDDLSGGVTPDMVTFAKGVAGGFPMGGMIAFGEKLAALFTPGSHGSTFAGNPLG
AAAGLATLDVIEDENLVTNAEARGKQLRDGIMATGNPLFVSVRGRGLLDAVELKHPCSHAVMNYCLEHGLIVNAVAPNAL
RFAPPLIVTAQDVDQALAILKDVPTDLPDD

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=415, Percent_Identity=33.0120481927711, Blast_Score=218, Evalue=8e-57,
Organism=Homo sapiens, GI284507298, Length=309, Percent_Identity=33.9805825242718, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI13994255, Length=448, Percent_Identity=31.25, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=28.0660377358491, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24119277, Length=436, Percent_Identity=26.605504587156, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=27.3584905660377, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI188536080, Length=431, Percent_Identity=26.6821345707657, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679950, Length=431, Percent_Identity=26.6821345707657, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI38679946, Length=431, Percent_Identity=26.6821345707657, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=28.3163265306122, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789759, Length=386, Percent_Identity=37.0466321243523, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1788044, Length=386, Percent_Identity=37.3056994818653, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI145693181, Length=382, Percent_Identity=38.4816753926702, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1789016, Length=414, Percent_Identity=33.8164251207729, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787560, Length=411, Percent_Identity=32.6034063260341, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786991, Length=418, Percent_Identity=26.7942583732057, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786349, Length=348, Percent_Identity=27.8735632183908, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=402, Percent_Identity=32.3383084577114, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=32.3725055432373, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144274, Length=284, Percent_Identity=32.7464788732394, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=26.4775413711584, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=421, Percent_Identity=26.8408551068884, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=31.0126582278481, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=34.0909090909091, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323470, Length=414, Percent_Identity=35.2657004830918, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=320, Percent_Identity=27.1875, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321456, Length=448, Percent_Identity=27.2321428571429, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357415, Length=398, Percent_Identity=34.4221105527638, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI161085790, Length=444, Percent_Identity=31.5315315315315, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28574759, Length=453, Percent_Identity=31.1258278145695, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=28.2710280373832, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=28.2710280373832, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=28.2710280373832, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=27.1461716937355, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45703; Mature: 45572

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEHEEKLGTEDSKWLGEYSQVHMNVFGTPLRVMDHGQGAHIWDVDGNEYLDFLAGIAV
CCCCCCHHCCCCHHHHHHHHHHEEHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHH
NSLGYAHPKWVKAVADQAAKVAHISNYFASEPQIELASKLVKLAGAPEGSKVYFGNSGAE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
GNEAALKLAKLYGRTLPDALPSIGGKPARILAMTHGFHGRTMGALSATWKPGIRKPYDPL
CHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
VPNIEFVRAGDKVALHDAFAQTGLGRYGKGPVAAVILELIQGEAGVQPLGADYVKFVREL
CCCEEEEECCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
CDINHALLIIDEVQTGIGRTGKWFAFQRDDLSGGVTPDMVTFAKGVAGGFPMGGMIAFGE
HCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
KLAALFTPGSHGSTFAGNPLGAAAGLATLDVIEDENLVTNAEARGKQLRDGIMATGNPLF
HHHHEECCCCCCCCCCCCCCHHHHHHHEEEEECCCCCEECCHHHHHHHHCCCEECCCEEE
VSVRGRGLLDAVELKHPCSHAVMNYCLEHGLIVNAVAPNALRFAPPLIVTAQDVDQALAI
EEECCCCCHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHH
LKDVPTDLPDD
HHHCCCCCCCC
>Mature Secondary Structure 
ATEHEEKLGTEDSKWLGEYSQVHMNVFGTPLRVMDHGQGAHIWDVDGNEYLDFLAGIAV
CCCCCHHCCCCHHHHHHHHHHEEHHHCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHH
NSLGYAHPKWVKAVADQAAKVAHISNYFASEPQIELASKLVKLAGAPEGSKVYFGNSGAE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
GNEAALKLAKLYGRTLPDALPSIGGKPARILAMTHGFHGRTMGALSATWKPGIRKPYDPL
CHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
VPNIEFVRAGDKVALHDAFAQTGLGRYGKGPVAAVILELIQGEAGVQPLGADYVKFVREL
CCCEEEEECCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
CDINHALLIIDEVQTGIGRTGKWFAFQRDDLSGGVTPDMVTFAKGVAGGFPMGGMIAFGE
HCCCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
KLAALFTPGSHGSTFAGNPLGAAAGLATLDVIEDENLVTNAEARGKQLRDGIMATGNPLF
HHHHEECCCCCCCCCCCCCCHHHHHHHEEEEECCCCCEECCHHHHHHHHCCCEECCCEEE
VSVRGRGLLDAVELKHPCSHAVMNYCLEHGLIVNAVAPNALRFAPPLIVTAQDVDQALAI
EEECCCCCHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHH
LKDVPTDLPDD
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]