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The map label for this gene is tig [H]

Identifier: 213692579

GI number: 213692579

Start: 1872890

End: 1874269

Strand: Reverse

Name: tig [H]

Synonym: Blon_1711

Alternate gene names: 213692579

Gene position: 1874269-1872890 (Counterclockwise)

Preceding gene: 213692580

Following gene: 213692578

Centisome position: 66.16

GC content: 63.41

Gene sequence:

>1380_bases
GTGAAGATCAGCGTTCGTAACCTCGAGCCCACCAAGGTGAAGCTCACCGTCACTGTTGAACCGGAAGAGCTCAACCCGTA
TCTGGATGCGGCCCGTAAGGAAATCGCCAAGCAGGTGAACGTTCCCGGCTTCCGTAAGGGCCACGTTCCCGGCAAGATCA
TCGACCAGCGCATCGGTTTCGCCGCCGTCGCCGGTGAGGCCGTGAACGACGCGGTCCCGGAGCTGTACTCCAAGGCCCTG
GATGAGAAGAAGATTCGTCCGATGGCTCAGCCGGAGTTCGACGTGCAGGATGTTCCGCAGTCCGCCAACGACGAGACCAA
GCTGAAGTTCACCGCCACCGTCGAGCGTCGTCCTGACATCGAACTGCCGGAAATCGACGGTCTTGAGATCGCCATCTCCA
AGCCGGAAGTCAAGGATGAGGACGTCGACAAGCGCCTCGAGACCCTGCGTCAGCGCTTCGGCACCTTGGTCGGCGTGGAC
CGCCCGGCCGCCAAGGGCGACTTCGCCAACATCGACCTGACTGCTGAGATTGACGGCGAGACCGTCGACTCCCAGGAAGG
CGTGAGCTACGAGCTCGGCTCCAACACCATGCTCGACGGTCTGGACGAGGCCCTTGACGGCCTGTCCGCCGGCGAGGAGA
CCACCTTCGAAGGCACGCTGGAAGCCGGCGAGCACGAGGGTCAGAAGGCCACCGTGAAGGTCAAGGTCAACTCCGTCAAG
GCTGAGGAACTGCCGGAGCTGGACGATGAGTTCGCTTCCGAAGCTTCCGAGTTCGACACCCTGGACGAGCTCAAGGCCGA
CATCCGCAAGGCTGCCGCTCAGGACGCCGAAGGCCGTCAGGCCACCGAGGCCCGCGATGCCTTCATCGCCAAGCTGCAGG
AAGGCCTCGAGATCCCGGTGCCGAAGGGCGTCAAGGCCAACATGGTCGAAGAGCAGCTCAAGGGCCTGACCCCGGACCCG
GAGAAGGCCACCAAGGAGCAGAAGGCTCAGGCCGAGGAGACCGTGGAGAAGGATCTGCGCGATCAGATGGTGCTCGACGC
TCTGGCCGAGAAGCTGGACGTTCAGGTGTCCCAGTCCGACGTGTTCAACTTCCTCGCTTCCATCGCCCAGCAGTACGGCA
TGGACCCGAACAACTTCATCCAGGCCATCATCAAGAACGGCCAGCTTGGCTCCGCTGTGCAGGAAGTCGCCCGCTCCAAG
GGTCTGCTCGCCGGCATGCGCGCCGTCAAGTTCACCGCTGATGGCGAGGTTGTGGACCTCTCCGGCTTCCTGGGCGAGGC
CGCTGAGGACGAAGAGTCCGAGTCCGTCGAGGCCGCTTCCGCTGCTGCCGCCGTGGCCGACGAACTGTCCGCCAAGGATG
ACGCCAAGGATGCTGAGTGA

Upstream 100 bases:

>100_bases
GCAGGTGAAACTCATTGCACCGTCCGTAAGTGGCGTTATCATGTAGAGGTTGCCTTACGGCAGAACTGTAAGAAATAACG
ACTTTTGAGGAGTCATTAGC

Downstream 100 bases:

>100_bases
GCATAGCCTCATCGCGTTAGCGTGATTGTTTGAGCCCGGAGTCGTGTTTCACGGTTCCGGGCTCTTCATATTCTGGCAAA
AGGACTATTTCTTTGGCTCC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKISVRNLEPTKVKLTVTVEPEELNPYLDAARKEIAKQVNVPGFRKGHVPGKIIDQRIGFAAVAGEAVNDAVPELYSKAL
DEKKIRPMAQPEFDVQDVPQSANDETKLKFTATVERRPDIELPEIDGLEIAISKPEVKDEDVDKRLETLRQRFGTLVGVD
RPAAKGDFANIDLTAEIDGETVDSQEGVSYELGSNTMLDGLDEALDGLSAGEETTFEGTLEAGEHEGQKATVKVKVNSVK
AEELPELDDEFASEASEFDTLDELKADIRKAAAQDAEGRQATEARDAFIAKLQEGLEIPVPKGVKANMVEEQLKGLTPDP
EKATKEQKAQAEETVEKDLRDQMVLDALAEKLDVQVSQSDVFNFLASIAQQYGMDPNNFIQAIIKNGQLGSAVQEVARSK
GLLAGMRAVKFTADGEVVDLSGFLGEAAEDEESESVEAASAAAAVADELSAKDDAKDAE

Sequences:

>Translated_459_residues
MKISVRNLEPTKVKLTVTVEPEELNPYLDAARKEIAKQVNVPGFRKGHVPGKIIDQRIGFAAVAGEAVNDAVPELYSKAL
DEKKIRPMAQPEFDVQDVPQSANDETKLKFTATVERRPDIELPEIDGLEIAISKPEVKDEDVDKRLETLRQRFGTLVGVD
RPAAKGDFANIDLTAEIDGETVDSQEGVSYELGSNTMLDGLDEALDGLSAGEETTFEGTLEAGEHEGQKATVKVKVNSVK
AEELPELDDEFASEASEFDTLDELKADIRKAAAQDAEGRQATEARDAFIAKLQEGLEIPVPKGVKANMVEEQLKGLTPDP
EKATKEQKAQAEETVEKDLRDQMVLDALAEKLDVQVSQSDVFNFLASIAQQYGMDPNNFIQAIIKNGQLGSAVQEVARSK
GLLAGMRAVKFTADGEVVDLSGFLGEAAEDEESESVEAASAAAAVADELSAKDDAKDAE
>Mature_459_residues
MKISVRNLEPTKVKLTVTVEPEELNPYLDAARKEIAKQVNVPGFRKGHVPGKIIDQRIGFAAVAGEAVNDAVPELYSKAL
DEKKIRPMAQPEFDVQDVPQSANDETKLKFTATVERRPDIELPEIDGLEIAISKPEVKDEDVDKRLETLRQRFGTLVGVD
RPAAKGDFANIDLTAEIDGETVDSQEGVSYELGSNTMLDGLDEALDGLSAGEETTFEGTLEAGEHEGQKATVKVKVNSVK
AEELPELDDEFASEASEFDTLDELKADIRKAAAQDAEGRQATEARDAFIAKLQEGLEIPVPKGVKANMVEEQLKGLTPDP
EKATKEQKAQAEETVEKDLRDQMVLDALAEKLDVQVSQSDVFNFLASIAQQYGMDPNNFIQAIIKNGQLGSAVQEVARSK
GLLAGMRAVKFTADGEVVDLSGFLGEAAEDEESESVEAASAAAAVADELSAKDDAKDAE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=308, Percent_Identity=27.5974025974026, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 49641; Mature: 49641

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISVRNLEPTKVKLTVTVEPEELNPYLDAARKEIAKQVNVPGFRKGHVPGKIIDQRIGF
CEEECCCCCCCEEEEEEEECHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCH
AAVAGEAVNDAVPELYSKALDEKKIRPMAQPEFDVQDVPQSANDETKLKFTATVERRPDI
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCC
ELPEIDGLEIAISKPEVKDEDVDKRLETLRQRFGTLVGVDRPAAKGDFANIDLTAEIDGE
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
TVDSQEGVSYELGSNTMLDGLDEALDGLSAGEETTFEGTLEAGEHEGQKATVKVKVNSVK
CCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCC
AEELPELDDEFASEASEFDTLDELKADIRKAAAQDAEGRQATEARDAFIAKLQEGLEIPV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
PKGVKANMVEEQLKGLTPDPEKATKEQKAQAEETVEKDLRDQMVLDALAEKLDVQVSQSD
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VFNFLASIAQQYGMDPNNFIQAIIKNGQLGSAVQEVARSKGLLAGMRAVKFTADGEVVDL
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHEEEECCCCEEEC
SGFLGEAAEDEESESVEAASAAAAVADELSAKDDAKDAE
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKISVRNLEPTKVKLTVTVEPEELNPYLDAARKEIAKQVNVPGFRKGHVPGKIIDQRIGF
CEEECCCCCCCEEEEEEEECHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCH
AAVAGEAVNDAVPELYSKALDEKKIRPMAQPEFDVQDVPQSANDETKLKFTATVERRPDI
HHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCC
ELPEIDGLEIAISKPEVKDEDVDKRLETLRQRFGTLVGVDRPAAKGDFANIDLTAEIDGE
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCC
TVDSQEGVSYELGSNTMLDGLDEALDGLSAGEETTFEGTLEAGEHEGQKATVKVKVNSVK
CCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCC
AEELPELDDEFASEASEFDTLDELKADIRKAAAQDAEGRQATEARDAFIAKLQEGLEIPV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
PKGVKANMVEEQLKGLTPDPEKATKEQKAQAEETVEKDLRDQMVLDALAEKLDVQVSQSD
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VFNFLASIAQQYGMDPNNFIQAIIKNGQLGSAVQEVARSKGLLAGMRAVKFTADGEVVDL
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHEEEECCCCEEEC
SGFLGEAAEDEESESVEAASAAAAVADELSAKDDAKDAE
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA