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The map label for this gene is rnd [H]

Identifier: 213692580

GI number: 213692580

Start: 1874324

End: 1875625

Strand: Reverse

Name: rnd [H]

Synonym: Blon_1712

Alternate gene names: 213692580

Gene position: 1875625-1874324 (Counterclockwise)

Preceding gene: 213692581

Following gene: 213692579

Centisome position: 66.21

GC content: 60.98

Gene sequence:

>1302_bases
TTGAGTGACGTCCGTGACACCGAACCCCGACTGCTGAAAGAGCCTCGCGGGGGAGTGCCCGATGTCACTTCGACGCTGGA
TGGCTATCATCGTGCCTGCGATGCGCTGGCCGAGGCGACGGGCTCGCTGGCCGCCGACGCCGAACGTGCGTCTGGATTCC
GCTATGGACATGAGGATTGGCTGATTCAGTTCAAACGTGAAGGCGCGGGCATCGCCTTGCTTGATCCCGTCGCCCTGACA
CGGGCCGGAGCTGACTGGAATGAATTCAATGACGCCGTGGGCGACGCTACGTGGATTCTGCATGATTCTCTGATGGACTT
GCCTGGATTCGCCGAAATCGGACTCAAACCCAAGGCCTTGTTCGACACGGAAATAGCGGCGCGATTGCTCGGCCTGCACC
GCTTCGGTCTGGCCGCCGTCACCGAACATTACCTCGGCATCACGCTGGCCAAAGAGCATTCCGCCGCCGATTGGTCCTAC
CGTCCGCTGCCGCGCGACTGGCGCAACTATGCTGCGCTCGACGTGGAGGTGCTTATCGAACTCGAAACCTTGATGCGTCG
TGACCTGAAAGCCGCAGGCAAGGATGAGTGGGCCGCTGAAGAGTTTTCTCACGCTTTGGTTGCGGGCCTTGCCCCGCGCA
AACTGCATCCGATTCCTTGGCTGCGTATCTCGCGCATCACCCAGCTGAGTCGTGATCCAAGGGGCTTGGCCATCGCCAAA
TCCCTATGGGAGGAGCGCGACCGGCTCGCCCGGCAATACGATATTGCCCCCAGCCTGTTATTGACCGATTCGTCAATCAT
CGAGGCCGCGACCAACAAGCCGCACAATGCCGCCCAATTCCGCGCGCTCCGATCCCTGAACGAGCGTGTGCGCATCCATA
CCGGTACCGAGCAGGACAAAATGTTCGAGCGGTACGCGCCGATTCAGCGTACAGTCAAACCGAAGGTCTGGAAGCAGGCC
ATCGACCGAGCCATGGCCCTGAAGCCCACCCAATGGCCTACCATGCCTGCCCCCGAACAGGGCGAAAACGGTGTGGTGAA
CGCGCCCCGATCCATGCGACTGTGGCAACAGCGCCATCCGGAGCGTTATGACCGTCTGCAACGGGTACGGCGTGTGATCA
ACCGCATCGCCGAAGACACCCGCACGCCGGCCGAGATGATCATCAAGCCACAGGCCCTACGCAACCTGTGCTGGGTGGAA
GACCCGGTGGAAGTGGACGTCGAGGCGTTCCTGATCGAGCAGGGCGCAAGGAACTGGCAGGTGAAACTCATTGCACCGTC
CGTAAGTGGCGTTATCATGTAG

Upstream 100 bases:

>100_bases
ACGGGACCGGACCGGACGGTACTATGGACGCCGGCGCACAAATCCGCTCGTGGGCCGCATTCATCAGATCCACCATCCGT
TTTGAGGAGGATGACGCCAG

Downstream 100 bases:

>100_bases
AGGTTGCCTTACGGCAGAACTGTAAGAAATAACGACTTTTGAGGAGTCATTAGCGTGAAGATCAGCGTTCGTAACCTCGA
GCCCACCAAGGTGAAGCTCA

Product: 3'-5' exonuclease

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSDVRDTEPRLLKEPRGGVPDVTSTLDGYHRACDALAEATGSLAADAERASGFRYGHEDWLIQFKREGAGIALLDPVALT
RAGADWNEFNDAVGDATWILHDSLMDLPGFAEIGLKPKALFDTEIAARLLGLHRFGLAAVTEHYLGITLAKEHSAADWSY
RPLPRDWRNYAALDVEVLIELETLMRRDLKAAGKDEWAAEEFSHALVAGLAPRKLHPIPWLRISRITQLSRDPRGLAIAK
SLWEERDRLARQYDIAPSLLLTDSSIIEAATNKPHNAAQFRALRSLNERVRIHTGTEQDKMFERYAPIQRTVKPKVWKQA
IDRAMALKPTQWPTMPAPEQGENGVVNAPRSMRLWQQRHPERYDRLQRVRRVINRIAEDTRTPAEMIIKPQALRNLCWVE
DPVEVDVEAFLIEQGARNWQVKLIAPSVSGVIM

Sequences:

>Translated_433_residues
MSDVRDTEPRLLKEPRGGVPDVTSTLDGYHRACDALAEATGSLAADAERASGFRYGHEDWLIQFKREGAGIALLDPVALT
RAGADWNEFNDAVGDATWILHDSLMDLPGFAEIGLKPKALFDTEIAARLLGLHRFGLAAVTEHYLGITLAKEHSAADWSY
RPLPRDWRNYAALDVEVLIELETLMRRDLKAAGKDEWAAEEFSHALVAGLAPRKLHPIPWLRISRITQLSRDPRGLAIAK
SLWEERDRLARQYDIAPSLLLTDSSIIEAATNKPHNAAQFRALRSLNERVRIHTGTEQDKMFERYAPIQRTVKPKVWKQA
IDRAMALKPTQWPTMPAPEQGENGVVNAPRSMRLWQQRHPERYDRLQRVRRVINRIAEDTRTPAEMIIKPQALRNLCWVE
DPVEVDVEAFLIEQGARNWQVKLIAPSVSGVIM
>Mature_432_residues
SDVRDTEPRLLKEPRGGVPDVTSTLDGYHRACDALAEATGSLAADAERASGFRYGHEDWLIQFKREGAGIALLDPVALTR
AGADWNEFNDAVGDATWILHDSLMDLPGFAEIGLKPKALFDTEIAARLLGLHRFGLAAVTEHYLGITLAKEHSAADWSYR
PLPRDWRNYAALDVEVLIELETLMRRDLKAAGKDEWAAEEFSHALVAGLAPRKLHPIPWLRISRITQLSRDPRGLAIAKS
LWEERDRLARQYDIAPSLLLTDSSIIEAATNKPHNAAQFRALRSLNERVRIHTGTEQDKMFERYAPIQRTVKPKVWKQAI
DRAMALKPTQWPTMPAPEQGENGVVNAPRSMRLWQQRHPERYDRLQRVRRVINRIAEDTRTPAEMIIKPQALRNLCWVED
PVEVDVEAFLIEQGARNWQVKLIAPSVSGVIM

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=284, Percent_Identity=28.8732394366197, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 48963; Mature: 48832

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVRDTEPRLLKEPRGGVPDVTSTLDGYHRACDALAEATGSLAADAERASGFRYGHEDW
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
LIQFKREGAGIALLDPVALTRAGADWNEFNDAVGDATWILHDSLMDLPGFAEIGLKPKAL
EEEEECCCCCEEEECHHHHHHCCCCHHHHHHHHCCHHHEEHHHHHCCCCHHHHCCCCHHH
FDTEIAARLLGLHRFGLAAVTEHYLGITLAKEHSAADWSYRPLPRDWRNYAALDVEVLIE
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LETLMRRDLKAAGKDEWAAEEFSHALVAGLAPRKLHPIPWLRISRITQLSRDPRGLAIAK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHH
SLWEERDRLARQYDIAPSLLLTDSSIIEAATNKPHNAAQFRALRSLNERVRIHTGTEQDK
HHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHCEEEECCCCHHH
MFERYAPIQRTVKPKVWKQAIDRAMALKPTQWPTMPAPEQGENGVVNAPRSMRLWQQRHP
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
ERYDRLQRVRRVINRIAEDTRTPAEMIIKPQALRNLCWVEDPVEVDVEAFLIEQGARNWQ
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEE
VKLIAPSVSGVIM
EEEECCCCCCCCC
>Mature Secondary Structure 
SDVRDTEPRLLKEPRGGVPDVTSTLDGYHRACDALAEATGSLAADAERASGFRYGHEDW
CCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
LIQFKREGAGIALLDPVALTRAGADWNEFNDAVGDATWILHDSLMDLPGFAEIGLKPKAL
EEEEECCCCCEEEECHHHHHHCCCCHHHHHHHHCCHHHEEHHHHHCCCCHHHHCCCCHHH
FDTEIAARLLGLHRFGLAAVTEHYLGITLAKEHSAADWSYRPLPRDWRNYAALDVEVLIE
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LETLMRRDLKAAGKDEWAAEEFSHALVAGLAPRKLHPIPWLRISRITQLSRDPRGLAIAK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHH
SLWEERDRLARQYDIAPSLLLTDSSIIEAATNKPHNAAQFRALRSLNERVRIHTGTEQDK
HHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHCEEEECCCCHHH
MFERYAPIQRTVKPKVWKQAIDRAMALKPTQWPTMPAPEQGENGVVNAPRSMRLWQQRHP
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
ERYDRLQRVRRVINRIAEDTRTPAEMIIKPQALRNLCWVEDPVEVDVEAFLIEQGARNWQ
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCEE
VKLIAPSVSGVIM
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]